Abstract: The invention relates to an automated system and method of communication between a pharmacy and a patient, preferably via text messaging, voice messaging or email. According to an exemplary embodiment, the system and method of the invention automatically notifies a patient in real-time when a pharmacy receives a prescription from the patient's prescriber. The system and method of the invention provides the patient with an opportunity to respond with their plans for the prescription such as to allow a patient to dictate their desired pickup time for the prescription or alert the pharmacy that they don't want the prescription filled at all for example.