Patents by Inventor David Filman

David Filman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligomerization of hepatitis delta antigen
    Publication number: 20050170337
    Abstract: This invention relates to HDAg peptides, including mutants, derivatives fragments and fusion molecules, including fusion proteins, coiled-coil oligomers, nucleic acid molecules, vectors comprising HDAg nucleic acid molecules, cells comprising said molecules, methods of multivalent expression and association of binding moieties of HDAg fusion molecules, and methods of use involving the molecules. The molecules are particularly useful as a framework for multivalent display via formation of C-terminal and/or N-terminal fusion proteins or via chemical coupling to chemically reactive sidechains, e.g. cysteine residues.
    Type: Application
    Filed: January 18, 2005
    Publication date: August 4, 2005
    Applicant: President and Fellows of Harvard College
    Inventors: James Hogle, Harmon Zuccola, David Filman, Carl Elkin
  • Oligomerization of hepatitis delta antigen
    Patent number: 6844171
    Abstract: This invention relates to HDAg peptides, including mutants, derivatives fragments and fusion molecules, including fusion proteins, coiled-coil oligomers, nucleic acid molecules, vectors comprising HDAg nucleic acid molecules, cells comprising said molecules, methods of multivalent expression and association of binding moieties of HDAg fusion molecules, and methods of use involving the molecules. The molecules are particularly useful as a framework for multivalent display via formation of C-terminal and/or N-terminal fusion proteins or via chemical coupling to chemically reactive sidechains, e.g. cysteine residues.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: January 18, 2005
    Assignee: President and Fellows of Harvard College
    Inventors: James M. Hogle, Harmon J. Zuccola, David Filman, Carl Elkin