Abstract: A system for supplying streaming media or other media sources to clients, where said system minimizes the lag time perceived by the user during negotiation between media sources by outputting the media content remaining in the buffer while the system is negotiating connection and buffering information from a second media source.

Abstract: The invention provides devices for the disruption of one or more layers of skin and methods of their use to administer therapeutic agents, e.g., antigens or drugs. The devices are designed to disrupt a defined area of skin. The defined area can approximate the area that a patch or other suitable vehicle for therapeutic agent, e.g., drug or vaccine, delivery is designed to contact. Exemplary devices employ a mask to define the area to be disrupted. Other devices disrupt a defined area by rotating in place. For devices that employ a mask that is secured to the skin, the invention provides methods of disrupting the stratum corneum by first securing the mask to the skin and then disrupting the skin. For rotating devices, the disrupting member is simply placed against the skin and actuated to effect disruption.

Abstract: A system for supplying streaming media or other media sources to clients, where said system minimizes the lag time perceived by the user during negotiation between media sources by outputting the media content remaining in the buffer while the system is negotiating connection and buffering information from a second media source.