Abstract: A control system for controlling an infusion pump, including interface components for allowing a user to receive and provide information, a processor connected to the user interface components and adapted to provide instructions to the infusion pump, and a computer program having setup instructions that cause the processor to enter a setup mode upon the control system first being turned on. In the setup mode, the processor prompts the user, in a sequential manner, through the user interface components to input basic information for use by the processor in controlling the infusion pump, and allows the user to operate the infusion pump only after the user has completed the setup mode.

Abstract: This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO or glycerol.

Abstract: This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO or glycerol.

Abstract: Therapeutic viral formulations having enhanced storage stability are described. The formulations comprise a viral vector in addition to one or more of an aqueous cosolvent, a reversible viral-encoded protease inhibitor and a mild reducing agent or other agent that prevents specific degradation of viral components.

Abstract: Compositions and methods for enhancing introduction of therapeutic agents into the bladder epithelium for the treatment of bladder diseases and disorders such as bladder cancer are described. According to one method, the luminal surface of the bladder is contacted with a composition comprising a bladder enhancer and a therapeutic agent for the treatment of the bladder disease. According to an alternative method, the luminal surface of the bladder is first contacted with a pretreatment composition comprising a bladder enhancer and subsequently contacted with a composition comprising a therapeutic agent for the treatment of the bladder disease. The transduction enhancing agent can be a mono-, di-, or poly-saccharide having a lipophilic substituent such as n-dodecyl-?-D-maltoside (DDM). Compositions comprising a transduction enhancing agent and a therapeutic agent for the treatment of a bladder disease are also described.

Abstract: A control system for controlling an infusion pump, including interface components for allowing a user to receive and provide information, a processor connected to the user interface components and adapted to provide instructions to the infusion pump, and a computer program having setup instructions that cause the processor to enter a setup mode upon the control system first being turned on. In the setup mode, the processor prompts the user, in a sequential manner, through the user interface components to input basic information for use by the processor in controlling the infusion pump, and allows the user to operate the infusion pump only after the user has completed the setup mode.

Abstract: Agents and methods for enhancing recombinant virus transduction in the bladder epithelium are described. A first method involves contacting the luminal surface of the bladder with a composition comprising a transduction enhancing agent and an oncolytic virus. Alternatively, the luminal surface of the bladder can be contacted first with a pretreatment composition comprising a transduction enhancing agent and, subsequently, with a composition comprising an oncolytic virus. Bladder treatment compositions comprising a transduction enhancing agent and an oncolytic virus are also described.

Abstract: Agents and methods for enhancing recombinant virus transduction in the bladder epithelium are described. A first method involves contacting the luminal surface of the bladder with a composition comprising a transduction enhancing agent and an oncolytic virus. Alternatively, the luminal surface of the bladder can be contacted first with a pretreatment composition comprising a transduction enhancing agent and, subsequently, with a composition comprising an oncolytic virus. Bladder treatment compositions comprising a transduction enhancing agent and an oncolytic virus are also described.

Abstract: This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO or glycerol.

Abstract: A gas turbine engine airfoil is cast around a core having a plurality of legs to form matching flow channels in the airfoil. The legs have a tie extending therebetween to maintain alignment. And, the tie is relocated along the core span to reduce differential static pressure of the cooling air across the resulting tie hole formed by the core tie.

Abstract: Circuit configuration for degradation of the stored magnetic energy of a field winding of a generator, where a battery voltage is applied to the field winding, having a power switch that is in operative connection with the field winding and is controllable by timed pulses from a clock control and which controls the storage and degradation of energy of the field winding. A zener diode is arranged between the field winding and a control input of a power switch for control of the energy degradation of the field winding, in particular of the power switch.

Abstract: A voluntary closing prosthetic prehensor includes a locking mechanism which may be locked into any position, and released with a small amount of force. With locking enabled, the prehensor opens and closes normally until the user applies sufficient tension to the prehensor cable after the prehensor has closed upon an object. Then, a lever arm attached to the cable rotates, pulling a second cable which causes an elliptical cam to rotate such that its wider portion presses against a pawl, causing the pawl to rotate into engagement with a toothed sector, locking the prehensor closed. When the user releases the force on the cable, the lever arm is biased to return to its normal position, but the prehensor stays closed because the pawl remains engaged with the sector. The cam includes a ratcheting drum which takes up the slack in the second cable. To release the prehensor, the user applies a small amount of force to the first cable, moving the lever arm and pulling the second cable, which rotates the cam.

Abstract: A shroud includes a panel having leading and trailing edges and inner and outer surfaces extending therebetween. A cooling passage extends through the panel from adjacent the leading edge to an intermediate location and is generally parallel to the inner and outer surfaces. The cooling passage has an inlet for receiving cooling air from adjacent the panel outer surface, a plurality of spaced apart turbulators disposed adjacent to the panel inner surface, and an outlet disposed at the leading edge for discharging the cooling air from the passage.

Abstract: A turbine blade is provided which includes an airfoil section having a leading edge flow region and a trailing edge flow region. The leading edge flow region includes an inner cavity having a serpentine geometry and first and second air inlets. The first air inlet is at one end of the inner cavity and is coupled to a first conduit which supplies air coolant thereto. The leading edge flow region also includes a leading edge cavity having a plurality of air film holes at the leading edge of the blade. The leading edge cavity is coupled to the inner cavity by impingement holes therebetween. The leading edge flow region further includes a refresher passageway which connects the first conduit at the base of the blade with the second inlet of the inner cavity. The refresher passageway refreshes the airflow in the inner cavity after the airflow has flowed part way through the inner cavity and has become warmed.