Patents by Inventor David G. Covell

David G. Covell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treating renal cancer using 4-[bis[2-[(methylsulfonyl)oxy]ethyl]amino]-2-methyl-benzaldehyde
    Patent number: 8273797
    Abstract: The present invention features methods of treating a mammalian subject having renal cancer by administration of 4-[bis[2-[(methylsulfonyl)oxy]ethyl]amino]-benzaldehyde. The present invention further features administration protocols and dosing schedules for methods of treating patients having renal cancer and pharmaceutical compositions suitable for use in the treatment methods provided herein.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: September 25, 2012
    Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
    Inventors: Susan D. Mertins, Susan E. Bates, David G. Covell, Geoffrey W. Patton, Melinda G. Hollingshead, Rao Vishnuvajjalla
  • TREATING RENAL CANCER USING A 4-[BIS[2-[(METHYLSULFONYL)OXY]ETHYL]AMINO]-2-METHYL-BENZALDEHYDE
    Publication number: 20110269840
    Abstract: The present invention features methods of treating a mammalian subject having renal cancer by administration of certain dimethylsulfonate compounds, such as a 4-[bis[2-[(methylsulfonyl)oxy]ethyl]amino]-benzaldehyde. The present invention further features administration protocols and dosing schedules for methods of treating patients having renal cancer and pharmaceutical compositions suitable for use in the treatment methods provided herein.
    Type: Application
    Filed: July 5, 2011
    Publication date: November 3, 2011
    Inventors: Susan D. Mertins, Susan E. Bates, David G. Covell, Geoffrey W. Patton, Melinda G. Hollingshead, Rao Vishnuvajjalla
  • Treating renal cancer using a 4-[bis[2-[(methylsulfonyl)oxy]ethyl]amino]-benzaldehyde
    Patent number: 7989501
    Abstract: The present invention features methods of treating a mammalian subject having renal cancer by administration of certain dimethylsulfonate compounds, such as a 4-[bis[2-[(methylsulfonyl)oxy]ethyl]amino]-benzaldehyde. The present invention further features administration protocols and dosing schedules for methods of treating patients having renal cancer and pharmaceutical compositions suitable for use in the treatment methods provided herein.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: August 2, 2011
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Susan D. Mertins, Susan Elaine Bates, David G. Covell, Geoffrey W. Patton, Melinda G. Hollingshead, Rao Vishnuvajjalla
  • Modulating mxa expression
    Publication number: 20100041617
    Abstract: The invention provides compositions and methods for inhibiting cell motility, metastatic cancer and viral infections in a mammal that involve increasing the activity or expression of MxA.
    Type: Application
    Filed: September 27, 2005
    Publication date: February 18, 2010
    Inventors: Jane Trepel, Alexandra Lin, Sunmin Lee, Chand Khanna, Min-Jung Lee, Eun J. Chung, Ruilli Huang, David G. Covell
  • Thiolesters and uses thereof
    Patent number: 7625917
    Abstract: This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: December 1, 2009
    Inventors: James A. Turpin, Yongsheng Song, Ettore Appella, John K. Inman, David G. Covell, William G. Rice, Anders Wallqvist, Andrew Maynard, Mingjun Huang
  • Treating or Preventing Renal Cancer Using a Dimethane Sulfonate
    Publication number: 20090131536
    Abstract: The present invention features methods of treating renal cancer by administration of certain dimethylsulfonate compounds. The present invention further features administration protocols and dosing schedules for methods of treating patients suffering from renal cancer and pharmaceutical compositions suitable for use in the treatment methods provided herein.
    Type: Application
    Filed: October 14, 2005
    Publication date: May 21, 2009
    Applicant: GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Susan D. Mertins, Susan E. Bates, David G. Covell, Geoffrey W. Patton, Melinda G. Hollingshead, Rao Vishnuvajjalla
  • Thiolesters and uses thereof
    Publication number: 20040132785
    Abstract: This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.
    Type: Application
    Filed: December 16, 2003
    Publication date: July 8, 2004
    Applicant: The Government of the U. S.of America as Represented by The Sec. of Health and Human Svc.
    Inventors: James A. Turpin, Yongsheng Song, Ettore Appella, John K. Inman, David G. Covell, William G. Rice, Anders Wallqvist, Andrew Maynard, Mingjun Huang
  • Thiolesters and uses thereof
    Patent number: 6706729
    Abstract: This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.
    Type: Grant
    Filed: May 16, 2001
    Date of Patent: March 16, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: James A. Turpin, Yongsheng Song, Ettore Appella, John K. Inman, David G. Covell, William G. Rice, Anders Wallqvist, Andrew Maynard, Mingjun Huang
  • Benzoylalkylindolepyridinium componds and pharmaceutical compositions comprising such compounds
    Publication number: 20020182151
    Abstract: The design, synthesis and antiviral activity of certain antiviral compounds are disclosed examples of which are shown below. These compounds inhibit the reverse transcriptase enzymes of several retroviruses, including human immunodeficiency virus.
    Type: Application
    Filed: December 13, 2001
    Publication date: December 5, 2002
    Applicant: The Government of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
    Inventors: William G. Rice, Mingjun Huang, Robert W. Buckheit, David G. Covell, Grzegorz Czerwinski, Christopher J. Michejda, Vadim Makarov