Abstract: A wound dressing includes one or more layers containing a first anti-microbial agent and/or at least one zinc-containing agent.

Abstract: An apparatus for promoting the healing of an exuding wound includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained. The cover may form a substantially fluid-tight seal around the wound and permit fluid communication between the reservoir and a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A wound filler positioned between the wound and the wound cover includes a nonwoven material at least partially perforated by sonic welding.

Abstract: An apparatus for promoting the healing of an exuding wound includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained. The cover may form a substantially fluid-tight seal around the wound and permit fluid communication between the reservoir and a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A wound filler positioned between the wound and the wound cover includes a fibrous material treated with a surface modification additive.

Abstract: A method of bridging from a wound dressing to a wound port for negative pressure wound therapy includes positioning an elongate wick between a wound and a remote location with respect to the wound. The elongate wick includes a three-dimensional spacer fabric having an upper fabric layer spaced from a lower fabric layer by an intermediate layer of pile threads. The elongate wick is covered with a flexible wick cover such that an enclosure is formed around the elongate wick. A substantially fluid-tight seal is established between a first end of the elongate wick cover and the wound dressing such that a reservoir is defined over the wound in which a negative pressure may be maintained. A substantially fluid-tight seal is established between a second end of the elongate wick cover and a fluid port configured for connection to a source of negative pressure.

Abstract: A wound dressing includes one or more layers containing a first anti-microbial agent and at least one of: a chelating agent, and a second anti-microbial agent.

Abstract: A wound dressing has a micro-architecture to produce appropriate strains in cells to promote the healing a wound. The apparatus includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound, a vacuum source in fluid communication with the reservoir and suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound, and a porous structure positioned in contact with the wound for delivering micro-mechanical forces to localized areas of the wound. The porous structure comprises a three-dimensional film material having directional apertures formed therein.

Abstract: A method of treating a substrate having a charge bias with at least one antimicrobial agent to modify the release properties of the antimicrobial agent with respect to the substrate, the method includes eliminating, mitigating, or modifying the charge bias of the substrate by applying at least one first agent to the substrate, and applying the at least one antimicrobial agent to the substrate. Related articles are also described.

Abstract: A method for treating a wound that includes incorporating a wound dressing comprising a plurality of fibers, each fiber having a length of at least two (2) inches, into a wound to cause the walls of the wound to remain apart and allow the wound to heal from the inside to the outside, and removing the wound exudate.

Abstract: A portable system for subatmospheric pressure therapy in connection with healing a surgical wound includes a wound dressing dimensioned for positioning relative to a wound bed of a subject and a portable subatmospheric pressure mechanism dimensioned to be carried or worn by the subject. The subatmospheric pressure mechanism includes a housing having a control unit, a collection canister, and means for releasably connecting the housing and the canister. The collection canister collects exudates from the wound bed which has been removed under subatmospheric pressure supplied by the control unit. The connection means between the housing and the canister permits the removal of the canister for emptying thereof or replacement with a new collection canister.

Abstract: A wound dressing includes one or more layers containing a first anti-microbial agent and optionally at least one of: a chelating agent, a second anti-microbial agent, a zinc-containing agent, a cell-signaling agent, and an additional active ingredient or agent.

Abstract: About 0.01% to 10% of an antifoam silicone oil having a predetermined viscosity of at least about 100 cp is dispersed in an aqueous solution of a water-soluble gum having a viscosity within about 20% of the predetermined viscosity of the silicone oil. A substrate is contacted with the dispersion so as to form a dispersion-wetted substrate and at least a part of the aqueous solution is removed from the substrate, wherein the silicone oil remains in the substrate.

Abstract: A filter material for filtering leucocytes from a fraction of or whole human blood, comprises a web having a thickness of at least about 1 millimeter and a bulk density of about 0.05 to 0.4 g/cm.sup.3. The web has a plurality of interlocked matrix fibers distributed in the web to form a matrix thereof with spaces between adjacent interstices of interlocked fibers. The matrix fibers are composed mainly of about 1 to 3 micron diameter glass fibers, i.e. at least 75% of the weight of the web being the glass fibers. A plurality of fibrillated particles of textile fiber material, having a surface area of between 5 and 100 square meters per gram are disposed within the spaces of the matrix. The weight ratio of the fibrillated particles to the matrix fibers is between about 1:99 and 40:60. A thermoplastic binder is disposed at least at cross-over portions of the matrix fibers, with the amount of the binder being about 0.1% to 10% by weight of the web.

Abstract: A filter material for filtering leucocytes from a fraction of or whole human blood, comprises a textile web having a thickness of between about 2 millimeters to about 12 millimeters and a bulk density of about 0.05 to 0.4 g/cm.sup.3. The web has a plurality of interlocked textile fibers with average deniers between about 0.05 and 0.75 and average lengths between about 3 millimeters and 15 millimeters. The textile fibers are distributed in the web to form a matrix thereof with spaces between adjacent interstices of interlocked fibers. A plurality of fibrillated particles of textile fiber material, having a surface area of between 5 and 100 square meters per gram are disposed within the spaces of the matrix. The weight ratio of the fibrillated particles to the textile fibers is between about 1:99 and 40:60. A plurality of glass fibers, having an average diameter of between 0.1 and 5 microns and being about 2% to 85% of the web, also form part of the matrix.

Abstract: A filter material for filtering leucocytes from a fraction of or whole human blood, comprises a shape-sustaining laid textile web having a thickness of between about 2 millimeters to about 12 millimeters and a bulk density of about 0.05 to 0.4 g/cm.sup.3. The web has a plurality of interlocked, staple, textile fibers with average deniers between about 0.05 and 0.75 and average lengths between about 3 millimeters and 15 millimeters. The textile fibers are substantially uniformly distributed in the web so as to form a matrix of the textile fibers with spaces between adjacent interstices of interlocked fibers. A plurality of fibrillated particles of a polymeric material, e.g. a textile fiber material, having a surface area of between 5 and 60 square meters per gram are substantially disposed within the spaces of the matrix.