Patents by Inventor David G. Maskalick

David G. Maskalick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4617376
    Abstract: There is disclosed herein a process for the purification of glucagon from a glucagon salt cake containing pancreas gland-sourced glucagon, which comprises(1) dissolving said glucagon salt cake in an aqueous medium containing a water-miscible organic solvent;(2) contacting the glucagon salt cake solution with a hydrophobic adsorption support at a pH less than about 4 or greater than about 7.5 and at conditions under which the glucagon is adsorbed on said hydrophobic adsorption support;(3) eluting glucagon from said hydrophobic adsorption support with an aqueous solution containing a water-miscible organic solvent to obtain a first glucagon-containing solution;(4) contacting a solution containing glucagon eluted from said hydrophobic adsorption support, said solution having a pH of from about 7.5 to about 10.
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: October 14, 1986
    Assignee: Eli Lilly and Company
    Inventors: David G. Maskalick, Marie T. Anderson