Patents by Inventor David G. Streeter

David G. Streeter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor-associated antigen
    Patent number: 6632617
    Abstract: The invention provides a cDNA which encodes a TUAN. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of inflammatory and cell proliferative disorders, in particular, Crohn's disease and colon cancer. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: October 14, 2003
    Assignee: Incyte Corporation
    Inventors: Olga Bandman, Surya K. Goli, Purvi Shah, Neil C. Corley, David G. Streeter
  • Down syndrome critical region 1-like protein
    Publication number: 20030186333
    Abstract: The invention provides a Down syndrome critical region 1-like 1 protein, its encoding cDNAs, and antibodies that specifically bind the protein. The invention also provides for the use of these compositions in the diagnosis, prognosis, treatment and evaluation of progression and treatment of neurodegenerative disorders.
    Type: Application
    Filed: November 6, 2002
    Publication date: October 2, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Jeanne F. Loring, Debora W. Tingley, Carla M. Edwards, David G. Streeter
  • Detection of genes regulated by EGF in breast cancer
    Publication number: 20030170717
    Abstract: The present invention relates to a combination comprising a plurality of polynucleotide probes that are modulated in response to EGF and which are associated with breast cancer, and which may be used in their entirety or in part as to diagnose, to stage, to treat, or to monitor the treatment of a subject with a breast cancer.
    Type: Application
    Filed: April 3, 2003
    Publication date: September 11, 2003
    Applicant: Incyte Corporation
    Inventors: Mary Faris, David G. Streeter
  • Tumor suppressors
    Publication number: 20030138835
    Abstract: The invention provides a mammalian cDNA which encodes a mammalian MTSP. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of cancer, particularly breast cancer. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Application
    Filed: January 21, 2003
    Publication date: July 24, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Susan G. Stuart, Henry Yue, Mariah R. Baughn, David G. Streeter
  • Breast cancer marker
    Publication number: 20030124543
    Abstract: The invention provides a cDNA which encodes a protein differentially expressed in breast cancer. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of cancer, particularly a breast cancer. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Application
    Filed: February 20, 2002
    Publication date: July 3, 2003
    Inventors: Susan G. Stuart, David G. Streeter
  • Cell cycle protein
    Publication number: 20030082573
    Abstract: The invention provides a cDNA which encodes a CCP. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of cell proliferative disorders, particularly cancers of the breast and kidney. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Application
    Filed: April 15, 2002
    Publication date: May 1, 2003
    Inventors: Michael G. Walker, Henry Yue, Kavitha Thangavelu, David G. Streeter
  • Detection of genes regulated by EGF in breast cancer
    Patent number: 6544742
    Abstract: The present invention relates to a combination comprising a plurality of polynucleotide probes that are modulated in response to EGF and which are associated with breast cancer, and which may be used in their entirety or in part as to diagnose, to stage, to treat, or to monitor the treatment of a subject with a breast cancer.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: April 8, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Mary Faris, David G. Streeter
  • Down syndrome critical region 1-like proteins
    Patent number: 6524819
    Abstract: The invention provides a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the mammalian nucleic acid molecule for the characterization, diagnosis, evaluation, treatment, of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: February 25, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jeanne F. Loring, Debora W. Tingley, Carla M. Edwards, David G. Streeter
  • Human Sec6 vesicle transport protein
    Publication number: 20020055108
    Abstract: The invention provides a cDNA which encodes human Sec6 vesicle transport protein. It also provides for the use of the cDNA, protein, and antibodies in the diagnosis, prognosis, treatment and evaluation of therapies for cancers or a neurodegenerative disorder. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
    Type: Application
    Filed: June 13, 2001
    Publication date: May 9, 2002
    Inventors: Samuel T. Labrie, David G. Streeter
  • DNA encoding human RSEC6 related protein
    Patent number: 5989818
    Abstract: The invention provides a human rSec6 related vesicle transport protein (HSEC6) and polynucleotides which identify and encode HSEC6. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSEC6.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Samuel T. Labrie, David G. Streeter
  • Regulator of gene transcription
    Patent number: 5965706
    Abstract: The present invention provides a human regulator of gene transcription (HRGT) and polynucleotides which encode HRGT. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HRGT.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli, David G. Streeter
  • Regulation of gene transcription
    Patent number: 5776698
    Abstract: The present invention provides a human regulator of gene transcription (HRGT) and polynucleotides which encode HRGT. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HRGT.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: July 7, 1998
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli, David G. Streeter
  • Antimetastatic peptides with laminin activity
    Patent number: 5175251
    Abstract: Human laminin B.sub.1 peptides have been produced. The invention provides novel peptides which contain substantial amino acid sequence similarity to amino acids 897 to 936 in the human sequence. These peptides have been found to have enhanced antimetastatic activity.
    Type: Grant
    Filed: October 29, 1991
    Date of Patent: December 29, 1992
    Assignee: SRI International
    Inventors: Paul H. Johnson, Jerome B. Lazar, David G. Streeter