Patents by Inventor David G. Washburn

David G. Washburn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS
    Publication number: 20230103791
    Abstract: The present invention relates to Nav1.8 Inhibitor 2,3-dihydroquinazolin compounds of Formula (X): wherein Y?, X?, B?, R1?, R2?, R3?, R5?, R6?, R7?, and z1 are as defined herein; or pharmaceutically acceptable salts or tautomer forms thereof, corresponding pharmaceutical compositions or formulations, methods or processes of compound preparation, methods, compounds for use in, uses for and/or combination therapies for treating pain and/or pain-related or associated disease(s), disorder(s) or condition(s), respectively.
    Type: Application
    Filed: June 23, 2020
    Publication date: April 6, 2023
    Inventors: Roderick S. DAVIS, Mark ELBAN, Jie GUANG, Ming-Hsun HO, Tram H. HOANG, William H. MILLER, Joseph J. ROMANO, Mythily VIMAL, Maben YING, David G. WASHBURN
  • HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE
    Publication number: 20200095217
    Abstract: Disclosed are compounds having the formula: wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.
    Type: Application
    Filed: October 17, 2019
    Publication date: March 26, 2020
    Inventors: Sarah E. DOWDELL, Hilary Schenck EIDAM, Mark ELBAN, Ryan Michael FOX, Marlys HAMMOND, Mark A. HILFIKER, Tram H. HOANG, Lara KALLANDER, Brian Griffin LAWHORN, Sharada MANNS, Joanne PHILP, David G. WASHBURN, Guosen YE
  • Hydroxy formamide derivatives and their use
    Patent number: 10450288
    Abstract: Disclosed are compounds having the formula: wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: October 22, 2019
    Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Sarah E. Dowdell, Hilary Schenck Eidam, Mark Elban, Ryan Michael Fox, Marlys Hammond, Mark A. Hilfiker, Tram H. Hoang, Lara Kallander, Brian Griffin Lawhorn, Sharada Manns, Joanne Philp, David G. Washburn, Guosen Ye
  • N-HYDROXYFORMAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THEM FOR USE AS BMP l, TLL1 AND/OR TLL2 INHIBITORS
    Publication number: 20180362485
    Abstract: Compounds of Formulas (I) and (II): and salts thereof; methods of making and using the same, including use for inhibiting BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.
    Type: Application
    Filed: July 8, 2016
    Publication date: December 20, 2018
    Inventors: Carla A. DONATELLI, Sarah E. DOWDELL, Mark ELBAN, Mark A. HILFIKER, Tram H. HOANG, Dennis Alan HOLT, Sharada MANNS, Andrew MARCUS, Craig POTTEIGER, Raynold SHENJE, David G. WASHBURN
  • HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE
    Publication number: 20160340328
    Abstract: Disclosed are compounds having the formula: wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.
    Type: Application
    Filed: January 9, 2015
    Publication date: November 24, 2016
    Inventors: Sarah E. DOWDELL, Hilary Schenck EIDAM, Mark ELBAN, Ryan Michael FOX, Marlys HAMMOND, Mark A. HILFIKER, Tram H. HOANG, Lara KALLANDER, Brian Griffin LAWHORN, Sharada MANNS, Joanne PHILP, David G. WASHBURN, Guosen YE
  • 1H-Pyrrolo[2,3-B]Pyridines
    Publication number: 20120238588
    Abstract: Derivatives of pyrrolo[2,3-b]pyridine which are useful as SGK-1 kinase inhibitors are described herein. The invention described herein also describes pharmaceutical compositions containing derivatives of pyrrolo[2,3-b]pyridine and methods of using pyrrolo[2,3-b]pyridine derivatives and pharmaceutical compositions thereof in the treatment of diseases mediated by SGK-1.
    Type: Application
    Filed: March 27, 2012
    Publication date: September 20, 2012
    Inventors: James S. Frazee, Marlys Hammond, Sharada Manns, Scott Kevin Thompson, David G. Washburn, Kazuya Kano, Hiroko Nakamura
  • Pyrrolidinone anilines as progesterone receptor modulators
    Patent number: 7816395
    Abstract: The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, wherein R1, R2, and X are as defined herein. Compounds of the present invention are useful as progesterone receptor modulators.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: October 19, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: David G. Washburn, Tram H. Hoang
  • PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS
    Publication number: 20100210706
    Abstract: The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, wherein R1, R2, and X are as defined herein. Compounds of the present invention are useful as progesterone receptor modulators.
    Type: Application
    Filed: August 7, 2007
    Publication date: August 19, 2010
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: David G. Washburn, Scott Kevin Thompson, Marlys Hammond, James S. Frazee, Tram H. Hoang, Latisha C. Johnson
  • 1H-Pyrrolo[2,3-B]Pyridnes
    Publication number: 20090233955
    Abstract: Derivatives of pyrrolo[2,3-b]pyridine which are useful as SGK-1 kinase inhibitors are described herein. The invention described herein also describes pharmaceutical compositions containing derivatives of pyrrolo[2,3-b]pyridine and methods of using pyrrolo[2,3-b]pyridine derivatives and pharmaceutical compositions thereof in the treatment of diseases mediated by SGK-1.
    Type: Application
    Filed: December 8, 2005
    Publication date: September 17, 2009
    Inventors: James S. Frazee, Marlys Hammond, Sharada Manns, Scott Kevin Thompson, David G. Washburn, Kazuya Kano, Hiroko Nakamura
  • Cyanoarylamines
    Publication number: 20080194536
    Abstract: The present invention relates to a compound represented by the following formula: (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, or a combination thereof, wherein Ro, R1, R1?, R2, R2?, R3 and n are defined herein. The present invention further relates to a method of treating a patient from endometreosis or uterine fibroids.
    Type: Application
    Filed: April 14, 2006
    Publication date: August 14, 2008
    Inventors: Marlys Hammond, David G. Jones, Istvan Kaldor, Lara S. Kallander, Xi Lang, Scott Kevin Thompson, Philip Stewart Turnbull, David G. Washburn
  • PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS
    Publication number: 20080039517
    Abstract: The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, wherein R1, R2, and X are as defined herein. Compounds of the present invention are useful as progesterone receptor modulators.
    Type: Application
    Filed: August 7, 2007
    Publication date: February 14, 2008
    Inventors: David G. WASHBURN, Tram H. HOANG