Patents by Inventor David G. Zapol

David G. Zapol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240325672
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Application
    Filed: October 25, 2023
    Publication date: October 3, 2024
    Applicant: Third Pole, Inc.
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Patent number: 11911566
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: February 27, 2024
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Patent number: 11833309
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: December 5, 2023
    Assignee: Third Pole, Inc.
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Publication number: 20230263986
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Application
    Filed: December 13, 2022
    Publication date: August 24, 2023
    Applicant: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Patent number: 11524134
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: December 13, 2022
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Publication number: 20220339391
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 27, 2022
    Applicant: Third Pole, Inc.
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Patent number: 11376390
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: July 5, 2022
    Assignee: Third Pole, Inc.
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Publication number: 20220047837
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Application
    Filed: May 27, 2021
    Publication date: February 17, 2022
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Publication number: 20210407080
    Abstract: Cell identification and classification is a well-known problem in the pathology domain that help identify microenvironments. In addition to the characteristic of each cell, its interactions with the neighboring regions or other cells is also important. This involves correct identification of neighboring elements and analytically representing the interactions between them. This disclosure presents a system that combines many such features, some hand engineered and some machine derived through training of Deep Learning algorithms that can be used to study the microenvironments.
    Type: Application
    Filed: June 24, 2021
    Publication date: December 30, 2021
    Inventors: Evan Szu, Nishant Borude, Nivedita Suresh, Michael H. Chu, David G. Zapol, Vinona Bhatia, Darick M. Tong, Noriko Y. Tong, John Cheng, Clifford Szu, Eric J. Suba
  • Publication number: 20210268221
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Application
    Filed: March 10, 2021
    Publication date: September 2, 2021
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Patent number: 11033705
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Grant
    Filed: December 21, 2019
    Date of Patent: June 15, 2021
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Patent number: 10946163
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: March 16, 2021
    Assignee: Third Pole, Inc.
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Publication number: 20200390994
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Application
    Filed: June 23, 2020
    Publication date: December 17, 2020
    Inventors: Ian J. Gillerman, Gregory W. Hall, Wolfgang Scholz, David G. Zapol
  • Patent number: 10695523
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: June 30, 2020
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Ian J. Gillerman
  • Publication number: 20200139072
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Application
    Filed: December 21, 2019
    Publication date: May 7, 2020
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Publication number: 20200094011
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Application
    Filed: November 27, 2019
    Publication date: March 26, 2020
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Ian J. Gillerman
  • Patent number: 10576239
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: March 3, 2020
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Patent number: 10532176
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: January 14, 2020
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz
  • Publication number: 20190314596
    Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
    Type: Application
    Filed: April 18, 2019
    Publication date: October 17, 2019
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz
  • Publication number: 20190217042
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Application
    Filed: March 25, 2019
    Publication date: July 18, 2019
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler