Abstract: A device for mixing and dispensing a flowable material or mixture of materials, the device comprising a cup having a bottom with a protrusion having an opening; a plunger having a dispensing port and air vent holes; a plug; a nozzle; and, a lid. The plug can be associated with and plug the cup protrusion opening when the cup is being filled or mixed, or the plug can be associated with the plunger port to seal off the air vent holes when material is dispensed from the device. Also disclosed is a method of mixing and dispensing a flowable material.

Abstract: A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

Abstract: A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

Abstract: A device for mixing and dispensing a flowable material or mixture of materials, the device comprising a cup having a bottom with a protrusion having an opening; a plunger having a dispensing port and air vent holes; a plug; a nozzle; and, a lid. The plug can be associated with and plug the cup protrusion opening when the cup is being filled or mixed, or the plug can be associated with the plunger port to seal off the air vent holes when material is dispensed from the device. Also disclosed is a method of mixing and dispensing a flowable material.

Abstract: A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

Abstract: A device for mixing and dispensing a flowable material or mixture of materials, the device comprising a cup having a bottom with a protrusion having an opening; a plunger having a dispensing port and air vent holes; a plug; a nozzle; and, a lid. The plug can be associated with and plug the cup protrusion opening when the cup is being filled or mixed, or the plug can be associated with the plunger port to seal off the air vent holes when material is dispensed from the device. Also disclosed is a method of mixing and dispensing a flowable material.

Abstract: A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40?) of the inhalation actuated mechanism (18).

Abstract: A troche mold assembly includes a cover defining a receiving area and a tray removably positioned in the receiving area. The tray includes a frame having a top side and a bottom side opposite from the top side. The frame defines a plurality of cells, and each cell is configured to receive a medicament. The tray also includes a plurality of buttons. Each button is within a corresponding cell and is between the top side and the bottom side of the frame. In some aspects, wherein each button includes a center portion, a first hinge line adjacent to the cell wall, and a second hinge line between the first hinge line and the center portion. In various aspects, the cover includes a locating rib, and the tray is removably positioned within the receiving area such that the locating rib contacts the top side of the frame.

Abstract: A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40?) of the inhalation actuated mechanism (18).

Abstract: A system for providing a continuous flow of blood between two locations in a cardiovascular system of a patient is provided. The system includes a blood conduit having a proximal portion configured to be attached to an artery. The system also includes a distal portion configured to be inserted into a blood vessel at an insertion site and to be advanced there through to a location spaced apart from the insertion site. Moreover, the system includes a reinforcement member positioned at least partially about the blood conduit in at least one of the distal portion, the proximal portion, or a combination thereof.

Abstract: A delumper includes a housing defining a chamber in which edible material is received. The housing includes a screen having a plurality of holes and a plurality of inwardly extending fingers. The holes are sized such that edible material of a first diameter is capable of passing through the holes and edible material of a second, larger diameter is incapable of passing through the holes. The fingers are arranged in at least a first row, and the first row is located at or between a 5:00 position and a 7:30 position. The delumper further includes a rotatable shaft including a plurality of paddles spaced along a length of the shaft. When the shaft rotates, each of the paddles passes between adjacent fingers of the first row such that edible material located within the chamber is forced into contact with the fingers and cleaved by the paddles.

Abstract: A device for mixing and dispensing a flowable material or mixture of materials, the device comprising a cup having a bottom with a protrusion having an opening; a plunger having a dispensing port and air vent holes; a plug; a nozzle; and, a lid. The plug can be associated with and plug the cup protrusion opening when the cup is being filled or mixed, or the plug can be associated with the plunger port to seal off the air vent holes when material is dispensed from the device. Also disclosed is a method of mixing and dispensing a flowable material.

Abstract: A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40?) of the inhalation actuated mechanism (18).

Abstract: A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40?) of the inhalation actuated mechanism (18).

Abstract: A delumper includes a housing defining a chamber in which edible material is received. The housing includes a screen having a plurality of holes and a plurality of inwardly extending fingers. The holes are sized such that edible material of a first diameter is capable of passing through the holes and edible material of a second, larger diameter is incapable of passing through the holes. The fingers are arranged in at least a first row, and the first row is located at or between a 5:00 position and a 7:30 position. The delumper further includes a rotatable shaft including a plurality of paddles spaced along a length of the shaft. When the shaft rotates, each of the paddles passes between adjacent fingers of the first row such that edible material located within the chamber is forced into contact with the fingers and cleaved by the paddles.

Abstract: A connector for fluidly coupling proximal and distal tubular segments of a fluid conduit is provided. In one embodiment, a system is provided for providing continuous flow of blood between two locations in a patient's cardiovascular system. A first blood conduit is provided that has a distal portion and a proximal portion. The distal portion is adapted to be inserted into a blood vessel at an insertion site and to be advanced therethrough to a location spaced apart from the insertion site. The system is provided with a connector that has a distal portion adapted to be engaged with the proximal portion of the first blood conduit and a tubular body extending proximally of the distal portion. The tubular body is adapted to be inserted into and/or attached to an end of a second blood conduit, such as a vascular graft or the like.

Abstract: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravacularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved.

Abstract: A system for providing a continuous flow of blood between two locations in a cardiovascular system of a patient is provided. The system includes a blood conduit having a proximal portion configured to be attached to an artery. The system also includes a distal portion configured to be inserted into a blood vessel at an insertion site and to be advanced there through to a location spaced apart from the insertion site. Moreover, the system includes a reinforcement member positioned at least partially about the blood conduit in at least one of the distal portion, the proximal portion, or a combination thereof.

Abstract: A clutch mechanism 5 for use with a carrier of a linear drive device 1, where the mechanism 5 includes: a housing 3; a first gear 6 coupled to the housing 3 and having gear teeth 61 configured to engage a threaded shaft 2 of a linear drive device 1, so that rotation of the shaft 2 causes the housing 3 to move along the shaft 2 in a first mode of operation; and a first clutch arrangement associated with the first gear 6 and configured to prevent substantial rotation of the first gear 6 with respect to the housing 3 when a rotational force applied to the first gear 6 is less than a threshold force and to permit rotation of the first gear 6 with respect to the housing 3 when a rotational force applied to the first gear 6 is greater than the threshold force.

Abstract: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from interventional procedures. The vessel wound closure system comprises at least a biocompatible, viscoelastic, self-sealing septum material injected onto the adventitia of the target vessel prior to performance of an interventional procedure. The prior injected septum material remains and seals the puncture wound of the target vessel even after various components associated with accessing the target vessel and the performance of the interventional procedure are removed from the target vessel and the puncture wound.