Abstract: A hood safety system for a vehicle prevents a hood of the vehicle from being unlocked in a crash event. The system includes a hood locking mechanism and a crash safety mechanism attached to a front structure in a front section of the vehicle. The hood locking mechanism may manually release the hood from a locked position to an unlocked position. The crash safety mechanism includes a crash pin displaceable between an inactivated state and an activated state. In the inactivated state the crash pin is disengaged from the hood locking mechanism and, in the activated state, the crash pin engages the hood locking mechanism to prevent the hood locking mechanism from displacing the hood into the unlocked position. A front section of the vehicle, when deformed by a crash event, is configured to mechanically displace the crash pin from the inactivated state to the activated state.

Abstract: A method for unlocking a hood of a vehicle in which a latch and a safety catch are arranged for engaging a striker and a locking member is arranged for engaging the safety catch. The method includes displacing the safety catch if a predetermined vehicle condition is fulfilled from a closed state wherein the safety catch is in locking engagement with the striker to an open state where the safety catch is disengaged from the striker for moving the hood locking mechanism from the intermediate locked mode to an open mode.

Abstract: A hood safety system for a vehicle prevents a hood of the vehicle from being unlocked in a crash event. The system includes a hood locking mechanism and a crash safety mechanism attached to a front structure in a front section of the vehicle. The hood locking mechanism may manually release the hood from a locked position to an unlocked position. The crash safety mechanism includes a crash pin displaceable between an inactivated state and an activated state. In the inactivated state the crash pin is disengaged from the hood locking mechanism and, in the activated state, the crash pin engages the hood locking mechanism to prevent the hood locking mechanism from displacing the hood into the unlocked position. A front section of the vehicle, when deformed by a crash event, is configured to mechanically displace the crash pin from the inactivated state to the activated state.

Abstract: A method for unlocking a hood of a vehicle in which a latch and a safety catch are arranged for engaging a striker and a locking member is arranged for engaging the safety catch. The method includes displacing the safety catch if a predetermined vehicle condition is fulfilled from a closed state wherein the safety catch is in locking engagement with the striker to an open state where the safety catch is disengaged from the striker for moving the hood locking mechanism from the intermediate locked mode to an open mode.

Abstract: A method and a system for accessing through a second mobile telecommunication network to services offered by a first mobile telecommunication network comprising the steps of: establishing a first communication channel with the second network, based on a secondary SIM card; establishing a second communication channel with the first network using the first communication channel, wherein a user of the mobile communication device is authenticated using a primary SIM card; registering, through the second communication channel, the user of the mobile communication device into the first network using the information stored in the primary SIM card; and accessing from the mobile communication device to services offered by the first network through the second communication channel.

Abstract: A method and a system for accessing through a second mobile telecommunication network to services offered by a first mobile telecommunication network comprising the steps of establishing a first communication channel with the second network, based on a secondary SIM card; establishing a second communication channel with the first network using the first communication channel, wherein a user of the mobile communication device is authenticated using a primary SIM card; registering, through the second communication channel, the user of the mobile communication device into the first network using the information stored in the primary SIM card; and accessing from the mobile communication device to services offered by the first network through the second communication channel.

Abstract: The present invention relates to methods for the treatment of cancer based on the induction of the choline kinase beta (hereinafter ChoK?) activity as well as to methods for the design of personalized therapies and for determining the response of an agent capable of inducing choline kinase beta (hereinafter ChoK?) for the treatment of cancer as well as to methods for determining the prognosis of a patient based on the determination of the ChoK? expression levels as well as based on the determination of the relationship between the ChoK? and ChoK? expression levels. Finally, the invention relates to methods for determining the response of a patient who suffers from cancer to ChoK?-inhibiting agents based on the determination of the PEMT and/or ChoK? expression levels.

Abstract: The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder cancer in an individual, for determining the stage or severity of said cancer in the individual, or for monitoring the effect of the therapy administered to an individual having said cancer; to finding, identifying, developing and evaluating the efficacy of compounds for the therapy of said cancer, for the purpose of developing new medicinal products; as well as to agents inhibiting the expression and/or activity of the choline kinase alpha protein and/or the effects of this expression.

Abstract: The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder cancer in an individual, for determining the stage or severity of said cancer in the individual, or for monitoring the effect of the therapy administered to an individual having said cancer; to finding, identifying, developing and evaluating the efficacy of compounds for the therapy of said cancer, for the purpose of developing new medicinal products; as well as to agents inhibiting the expression and/or activity of the choline kinase alpha protein and/or the effects of this expression.

Abstract: The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder cancer in an individual, for determining the stage or severity of said cancer in the individual, or for monitoring the effect of the therapy administered to an individual having said cancer; to finding, identifying, developing and evaluating the efficacy of compounds for the therapy of said cancer, for the purpose of developing new medicinal products; as well as to agents inhibiting the expression and/or activity of the choline kinase alpha protein and/or the effects of this expression.

Abstract: The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder cancer in an individual, for determining the stage or severity of said cancer in the individual, or for monitoring the effect of the therapy administered to an individual having said cancer; to finding, identifying, developing and evaluating the efficacy of compounds for the therapy of said cancer, for the purpose of developing new medicinal products; as well as to agents inhibiting the expression and/or activity of the choline kinase alpha protein and/or the effects of this expression.

Abstract: The present invention relates to methods for the treatment of cancer based on the induction of the choline kinase beta (hereinafter ChoK?) activity as well as to methods for the design of personalized therapies and for determining the response of an agent capable of inducing choline kinase beta (hereinafter ChoK?) for the treatment of cancer as well as to methods for determining the prognosis of a patient based on the determination of the ChoK? expression levels as well as based on the determination of the relationship between the ChoK? and ChoK? expression levels. Finally, the invention relates to methods for determining the response of a patient who suffers from cancer to ChoK?-inhibiting agents based on the determination of the PEMT and/or ChoK? expression levels.

Abstract: The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder cancer in an individual, for determining the stage or severity of said cancer in the individual, or for monitoring the effect of the therapy administered to an individual having said cancer; to finding, identifying, developing and evaluating the efficacy of compounds for the therapy of said cancer, for the purpose of developing new medicinal products; as well as to agents inhibiting the expression and/or activity of the choline kinase alpha protein and/or the effects of this expression.

Abstract: A brush cover is provided with a retention mechanism for releasably securing a brush having a bristle portion on a distal end and an interconnected elongate handle proximal to the bristle portion. The brush cover includes an elongate sleeve having an outer surface, an inner surface, an open proximal end and an open distal end for receiving and withdrawing the brush relative to the elongated sleeve. The elongate sleeve of the brush cover also includes a retention mechanism. The retention mechanism is attached to the inner surface of the elongate sleeve and positioned within the elongate sleeve to intermittently contact an area of the elongate handle. The intermittent contact between the handle of the brush and the retention mechanism allows for the brush to be releasably secured within the elongate sleeve. The bristle portion of the brush is covered by the distal end of the elongate sleeve.