Patents by Inventor David Gene Barrett

David Gene Barrett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GPR119 agonists
    Patent number: 8207344
    Abstract: GPR119 agonist compounds of the formula: and pharmaceutical compositions for the treatment of diabetes and obesity.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: June 26, 2012
    Assignee: Eli Lilly and Company
    Inventors: David Gene Barrett, Ana Belen Bueno Melendo, Jeffry Bernard Franciskovich, Bin Liu, Kumiko Takeuchi
  • GPR119 Agonists
    Publication number: 20110015199
    Abstract: GPR119 agonist compounds of the formula: and pharmaceutical compositions for the treatment of diabetes and obesity.
    Type: Application
    Filed: July 12, 2010
    Publication date: January 20, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: David Gene Barrett, Ana Belen Bueno Melendo, Jeffry Bernard Franciskovich, Bin Liu, Kumiko Takeuchi
  • Substituted arylcyclopropylacetamides as glucokinase activators
    Patent number: 7576108
    Abstract: According to the present invention there is provided a compounds of formula (I): and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: August 18, 2009
    Assignee: Eli Lilly and Company
    Inventors: Andreas Gerhard Weichert, David Gene Barrett, Stefan Heuser, Rainer Riedl, Mark Joseph Tebbe, Andrea Zaliani
  • Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin K inhibitors for the treatment of bone loss
    Patent number: 7402606
    Abstract: Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle substituted ketoamide derivatives as well as method of using the same in the manufacture of medicaments for the treatment of disorders, including osteoporosis, associated with an imbalance between bone resorption and formation which can ultimately lead to fracture.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: July 22, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: David Gene Barrett, John G. Catalano, David Norman Deaton, Aaron Bayne Miller, John A. Ray, Vicente Samano
  • Alpha-ketoamide derivatives as cathepsin k inhibitors
    Publication number: 20050107616
    Abstract: Biaryl ketoamide derivatives, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such biaryl ketoamide derivatives as well as methods of using the same in the treatment of disorders, including osteoporosis, associated with enhanced bone turnover which can ultimately lead to fracture.
    Type: Application
    Filed: July 23, 2002
    Publication date: May 19, 2005
    Inventors: David Gene Barrett, David Deaton, Robert Mcfadyen, Aaron Miller, John Ray, Francis Tavares, Huiqiang Zhou