Abstract: The invention provides a device and method for illuminating a body surface. A light source is optically coupled to the proximal end of a light guide and a light scatterer is optically coupled to the distal end of the light guide. The device includes a deployment mechanism that is configured to bring the light scatterer from a small caliber configuration in which the light scatterer is delivered to the body surface to a large caliber configuration in which the light scatterer irradiates the body surface. The invention may be used, for example, irradiate the periadventitial surface of an aneurysmal blood vessel.

Abstract: The present invention provides an apparatus and method for the internal treatment of body cavities and damaged internal vessels using irradiation. A device and method according to the invention may be used to irradiate an internal tissue surface, for example, for the treatment of an aneurysm, tissue welding, or the removal of a stenosis in a blood vessel. In one embodiment, the invention provides a device for illuminating a body surface including a shaft having a light guide, a control unit, and a light scatterer. The control unit includes a light source optically coupled to the light guide; and the light scatterer is optically coupled to the light guide. The light scatterer includes a first, rear surface and a second, forward illuminating surface, and the light scatterer has a first undeployed, collapsed configuration and a second deployed configuration in which the illuminating surface has a larger caliber than in the first undeployed, collapsed configuration.

Abstract: The invention provides a device and method for illuminating a body surface. A light source is optically coupled to the proximal end of a light guide and a light scatterer is optically coupled to the distal end of the light guide. The device includes a deployment mechanism that is configured to bring the light scatterer from a small caliber configuration in which the light scatterer is delivered to the body surface to a large caliber configuration in which the light scatterer irradiates the body surface. The invention may be used, for example, irradiate the periadventitial surface of an aneurysmal blood vessel.

Abstract: An isometric enriched tyrphostin of a general formula: wherein, for Compound I, the tyrphostin is enriched either for R6 at position 6 or for R6 at position 7, or, for Compound II, the tyrphostin is enriched either for R6 at position 6 or for R6 at position 8. Further disclosed are pharmaceutical compositons containing the isometric enriched tyrphostin and methods of using same to treat cell proliferative diseases.

Abstract: PDGF receptor kinase inhibitory compounds of the quinoxaline family, methods for their synthesis and containment is slow release pharmaceutical preparations, and their use for treatment of proliferative malignant and non-malignant diseases or disorders by local or systemic application. A compound according to the invention includes a tyrphostin of the general formula: ##STR1## wherein R1 and R2 are each independently selected from the group consisting of alkyl, alkoxy, halogen, nitro and amine and Ar is selected from the group consisting of phenyl, ferrocene, thiophene, furane, pyrrole, indole, thiazole, imidazole and pyridine.