Patents by Inventor David Gladstone

David Gladstone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260041936
    Abstract: A system provides a pulsed radiation beam along an axis; a scintillator blanket or a scintillator mask conformable to a surface of a target area of a patient; and a camera to image the scintillator from a distance. The system includes an image processor configured to use images of the scintillator to measure radiation dosage provided by each pulse of the beam, totalize radiation dosage provided by pulses of the beam, and provide signals to a controller. A method of monitoring radiation treatment includes placing a scintillator on a target area; providing a radiation beam through the scintillator into the target area; using a camera to image from a distance; and applying dose calibration factors, angular emission correction factors, and a measured 3D surface of the scintillator, to generate maps of dose and dose rate in a geometric plane perpendicular to an axis of the radiation beam.
    Type: Application
    Filed: June 18, 2024
    Publication date: February 12, 2026
    Inventors: PETR BRUZA, BRIAN POGUE, RAMISH ASHRAF, RONGXIAO ZHANG, DAVID GLADSTONE, MEGAN CLARK, ROMAN VASYLTSIV
  • Patent number: 12036421
    Abstract: A system for delivering ultra-high dose rate irradiation to a target area of a patient, includes a pulsed charged-particle source along a beam axis; a collimator for shaping the beam of radiation; one or more cameras for imaging the target area of the patient; and a dosimetry controller for providing control signals to the charged-particle source one or more dosimeters positioned between an output of the charged-particle source and the collimator in beam fringes for measuring a radiation dosage provided by each pulse; and a beam scanning coil positioned between the collimator and the patient for directing the shaped beam. The dosimetry controller receives feedback from the one or more dosimeters and provides control signals to the particle source and the beam scanning coil that modulate final pulses in the series of pulses in real-time.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: July 16, 2024
    Assignee: THE TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Petr Bruza, Brian Pogue, Ramish Ashraf, Rongxiao Zhang, David Gladstone, Megan Clark, Roman Vasyltsiv
  • Publication number: 20240173569
    Abstract: A system for delivering ultra-high dose rate irradiation to a target area of a patient, includes a pulsed charged-particle source along a beam axis; a collimator for shaping the beam of radiation; one or more cameras for imaging the target area of the patient; and a dosimetry controller for providing control signals to the charged-particle source one or more dosimeters positioned between an output of the charged-particle source and the collimator in beam fringes for measuring a radiation dosage provided by each pulse; and a beam scanning coil positioned between the collimator and the patient for directing the shaped beam. The dosimetry controller receives feedback from the one or more dosimeters and provides control signals to the particle source and the beam scanning coil that modulate final pulses in the series of pulses in real-time.
    Type: Application
    Filed: May 25, 2022
    Publication date: May 30, 2024
    Inventors: PETR BRUZA, BRIAN POGUE, RAMISH ASHRAF, RONGXIAO ZHANG, DAVID GLADSTONE
  • Patent number: 11633627
    Abstract: A Cherenkov-based or thin-sheet scintillator-based imaging system uses a radio-optical triggering unit (RTU) that detects scattered radiation in a fast-response scintillator to detect pulses of radiation to permit capture of Cherenkov-light or scintillator-light images during pulses of radiation and background images at times when pulses of radiation are not present without need for electrical interface to the accelerator that provides the pulses of radiation. The Cherenkov images are corrected by background subtraction and used for purposes including optimization of treatment, commissioning, routine quality auditing, R&D, and manufacture. The radio-optical triggering unit employs high-speed, highly sensitive radio-optical sensing to generate a digital timing signal which is synchronous with the treatment beam for use in triggering Cherenkov light or scintillator light imaging.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: April 25, 2023
    Assignees: THE TRUSTEES OF DARTMOUTH COLLEGE, DOSEOPTICS, LLC
    Inventors: Venkataramanan Krishnaswamy, Petr Bruza, Jr., Michael Jermyn, Brian W. Pogue, David Gladstone, Lesley A. Jarvis, Irwin Tendler
  • Publication number: 20210275833
    Abstract: A Cherenkov-based or thin-sheet scintillator-based imaging system uses a radio-optical triggering unit (RTU) that detects scattered radiation in a fast-response scintillator to detect pulses of radiation to permit capture of Cherenkov-light or scintillator-light images during pulses of radiation and background images at times when pulses of radiation are not present without need for electrical interface to the accelerator that provides the pulses of radiation. The Cherenkov images are corrected by background subtraction and used for purposes including optimization of treatment, commissioning, routine quality auditing, R&D, and manufacture. The radio-optical triggering unit employs high-speed, highly sensitive radio-optical sensing to generate a digital timing signal which is synchronous with the treatment beam for use in triggering Cherenkov light or scintillator light imaging.
    Type: Application
    Filed: May 6, 2021
    Publication date: September 9, 2021
    Inventors: Venkataramanan Krishnaswamy, Petr Bruza, JR., Michael Jermyn, Brian W. Pogue, David Gladstone, Lesley A. Jarvis, Irwin Tendler
  • Publication number: 20210001153
    Abstract: A system for dosimetry includes a radiation source that provides a pulsed radiation beam to a treatment zone, and a thin sheet of scintillator disposed between the radiation source and skin of a subject in the treatment zone. A gated camera images the scintillator integrating light from the scintillator during multiple pulses of the radiation beam while excluding light received between pulses of the pulsed radiation beam; and an image capture and processing machine that receives images from the gated camera and performs additional corrections to provide a map of dose received by the subject.
    Type: Application
    Filed: February 22, 2019
    Publication date: January 7, 2021
    Inventors: Brian W. Pogue, Petr Bruza, David Gladstone, Lesley A. Jarvis, Irwin Tendler
  • Patent number: 5488908
    Abstract: In a preferred embodiment, an environmentally insensitive electric detonator system for demolition, including: an object to be demolished; a main explosive charge in proximity to the object to be demolished; electrically activated detonator apparatus including a relatively insensitive initiating charge in proximity to the main explosive charge; and circuitry having input apparatus to receive an input firing pulse and having output apparatus to provide, through arbitrarily long wires, a high voltage in response thereto across the electrically activated detonator apparatus to cause ignition of the main explosive charge.
    Type: Grant
    Filed: April 22, 1994
    Date of Patent: February 6, 1996
    Assignees: Paul C. Gilpin, Magnavox Electronic Systems Company
    Inventors: Paul C. Gilpin, David Gladstone