Abstract: A filtration unit intended to allow the selective elimination of target substances from a fluid such as flood or a blood component, has an outer envelope formed from two flexible sheets joined together over their periphery along a bond line so as to define an inner volume, the envelope containing a filtering medium which delimits, on both sides of the bond line, an inlet compartment of the fluid to be filtered and an outlet compartment of the filtrate, each of the compartments being provided with an element—respectively an inlet and outlet element—for bringing the compartment into communication with the outside, the elements being connected between the sheets and comprising a flow channel that passes through the bond line, the unit being characterized in that at least one channel is offset relative to the bond line towards the compartment with which the channel is in communication.

Abstract: A filtration unit for the selective elimination of a target substance from a biological fluid comprising an external envelope, wherein the envelope encloses a filtering medium comprising: an upstream structure for eliminating at least the target substance comprising a stack of layers that are arranged to allow the flow of fluid through the layers in one direction comprising a non-woven material, and particles interposed between at least some of the layers, wherein the particles have an affinity for the target substance; and a downstream structure for retaining the particles comprising at least one layer of porous material.

Abstract: The present invention includes a process for manufacturing metal sheets or plates and a machined metal part as well as machined products, structural components and their uses in various applications. Manufacture of a metal sheet or plate by a process of the present invention comprises casting of a rolling ingot, optionally followed by homogenisation, one or more hot or cold rolling operations, optionally separated by one or more re-heating operations, to obtain a sheet, or plate and optionally one or more sheet or plate cutting or finishing operations. The sheet is pre-machined on one or both sides so as to obtain a pre-machined stock, and subjected to solution heat treatment, quenching treatment, and optionally, one or more of the following steps: controlled stretching, aging treatment, and/or cutting.

Abstract: The present invention includes a process for manufacturing metal sheets or plates and a machined metal part as well as machined products, structural components and their uses in various applications. Manufacture of a metal sheet or plate by a process of the present invention comprises casting of a rolling ingot, optionally followed by homogenization, one or more hot or cold rolling operations, optionally separated by one or more re-heating operations, to obtain a sheet, or plate and optionally one or more sheet or plate cutting or finishing operations. The sheet is pre-machined on one or both sides so as to obtain a pre-machined stock, and subjected to solution heat treatment, quenching treatment, and optionally, one or more of the following steps: controlled stretching, aging treatment, and/or cutting.

Abstract: A filtration unit intended to allow the selective elimination of target substances from a fluid such as flood or a blood component, has an outer envelope formed from two flexible sheets joined together over their periphery along a bond line so as to define an inner volume, the envelope containing a filtering medium which delimits, on both sides of the bond line, an inlet compartment of the fluid to be filtered and an outlet compartment of the filtrate, each of the compartments being provided with an element—respectively an inlet and outlet element—for bringing the compartment into communication with the outside, the elements being connected between the sheets and comprising a flow channel that passes through the bond line, the unit being characterized in that at least one channel is offset relative to the bond line towards the compartment with which the channel is in communication.

Abstract: The present invention includes a process for manufacturing metal sheets or plates and a machined metal part as well as machined products, structural components and their uses in various applications. Manufacture of a metal sheet or plate by a process of the present invention comprises casting of a rolling ingot, optionally followed by homogenisation, one or more hot or cold rolling operations, optionally separated by one or more re-heating operations, to obtain a sheet, or plate and optionally one or more sheet or plate cutting or finishing operations. The sheet is pre-machined on one or both sides so as to obtain a pre-machined stock, and subjected to solution heat treatment, quenching treatment, and optionally, one or more of the following steps: controlled stretching, aging treatment, and/or cutting.

Abstract: A filtration unit for the selective elimination of a target substance from a biological fluid comprising an external envelope, wherein the envelope encloses a filtering medium comprising: an upstream structure for eliminating at least the target substance comprising a stack of layers that are arranged to allow the flow of fluid through the layers in one direction comprising a non-woven material, and particles interposed between at least some of the layers, wherein the particles have an affinity for the target substance; and a downstream structure for retaining the particles comprising at least one layer of porous material.

Abstract: The present invention includes a process for manufacturing metal sheets or plates and a machined metal part as well as machined products, structural components and their uses in various applications. Manufacture of a metal sheet or plate by a process of the present invention comprises casting of a rolling ingot, optionally followed by homogenisation, one or more hot or cold rolling operations, optionally separated by one or more re-heating operations, to obtain a sheet, or plate and optionally one or more sheet or plate cutting or finishing operations. The sheet is pre-machined on one or both sides so as to obtain a pre-machined stock, and subjected to solution heat treatment, quenching treatment, and optionally, one or more of the following steps: controlled stretching, aging treatment, and/or cutting.

Abstract: The present invention is directed to a metal block suitable for machining, the metal block comprising at least two superimposed metal plates, each having a thickness of at least 12.5 mm, wherein the yield strength of the block is at least 75% of the yield strength of the initial metal plate(s). The present invention is further directed to methods for manufacturing such blocks from two or more thick metal plates by explosive welding and other methods. Blocks according to the present invention are useful, for example, for manufacturing aircraft structural components or injection molds for plastics or rubber.

Abstract: The present invention is directed to a metal block suitable for machining, the metal block comprising at least two superimposed metal plates, each having a thickness of at least 12.5 mm, wherein the yield strength of the block is at least 75% of the yield strength of the initial metal plate(s).