Abstract: The present invention generally relates to the early prevention of overweight, obesity, excessive fat accumulation and/or associated metabolic disorders in infants or children. For example, the present invention relates to the prevention of overweight, obesity, excessive fat accumulation and/or associated metabolic disorders in infants or children through appropriate maternal nutrition for women desiring to get pregnant and/or during pregnancy and/or lactation. Embodiments of the present invention relate to the Vitamin B2 for use in the prevention of overweight, obesity, excessive fat accumulation and/or associated metabolic disorders in the offspring, wherein the vitamin B2 is administered to women desiring to get pregnant and/or to the mother during pregnancy and/or lactation and to maternal food compositions that can be used for this purpose.

Abstract: Hydrogels for entrapment of live microorganisms and methods of their use, such as in wastewater purification, are disclosed.

Abstract: Among other things, the present disclosure provides oligonucleotides and compositions thereof. In some embodiments, provided oligonucleotides and compositions are useful for adenosine modification. In some embodiments, the present disclosure provides methods for treating various conditions, disorders or diseases that can benefit from adenosine modification.

Abstract: Among other things, the present disclosure provides oligonucleotides and compositions thereof. In some embodiments, provided oligonucleotides and compositions are useful for adenosine modification. In some embodiments, the present disclosure provides methods for treating various conditions, disorders or diseases that can benefit from adenosine modification.

Abstract: Among other things, the present disclosure provides cells and non-human animals engineered to express an ADAR1 polypeptide or a characteristic portion thereof. In some embodiments, the present disclosure provides cells and non-human animals engineered to express a human ADAR1 polypeptide or a characteristic portion thereof. In some embodiments, non-human animals are genetically modified rodents such as mice, rat, etc. In some embodiments, non-human animals are mice. In some embodiments, the present disclosure provides technologies for assessing an agent comprising administering the agent to a cell or non-human animal engineered to express an ADAR1 polypeptide or a characteristic portion thereof. In some embodiments, such a cell or non-human animal is engineered to express a human ADAR1 polypeptide or a characteristic portion thereof. In some embodiments, an agent is a pharmaceutical agent. In some embodiments, an agent is or comprises an oligonucleotide.

Abstract: Among other things, the present disclosure provides oligonucleotides and compositions thereof. In some embodiments, provided oligonucleotides and compositions are useful for adenosine modification. In some embodiments, the present disclosure provides methods for treating various conditions, disorders or diseases that can benefit from adenosine modification.

Abstract: An applicator device for abutment by or attachment to a reciprocating mechanism of a viscous fluid material printing machine, the applicator device including: a body having a through passage with an upper, fluid inlet extending along the body and a lower, fluid outlet extending along the body; an elongate, horizontally-extending reservoir for fluid material formed with or detachably mounted on an upper side of the body and being in fluid communication with the inlet of the body; and a displaceable piston extending in the reservoir for displacing fluid material out of the reservoir into the inlet of the body and to the outlet of the body, with the piston being actuable from above by the reciprocating mechanism of the printing machine so as to be displaceable thereby and the applicator device being without and not requiring any other separate motive power source or pipe ducting means for such displacement.

Abstract: A support and tensioning frame for a stencil to enable solder paste to be applied to printed circuit boards and other electronic substrates includes a support frame engaged with at least two opposed mounting members. Each mounting member includes at least one projection for engaging an aperture in a stencil to mount the stencil under tension. A permanent-biasing mechanism engages one or more of the mounting members to place the stencil under tension. A second biasing mechanism engages the mounting member to provide a bias opposite that of the permanent-biasing mechanism to facilitate release of a mounted stencil.

Abstract: An application device for applying viscous or paste fluid material to a surface therebeneath and having a fluid outlet aperture in its lower region and including a sealing gasket or foil for sealing the outlet aperture against the surface. The gasket or foil is formed from a sheet of flexible material with an uninterrupted or continuous, non-apertured outer part extending around the periphery of the outlet aperture and surrounding an inner aperture or apertured inner region of the gasket or foil.

Abstract: A solder paste or other viscous material screen printing machine in combination with paste or viscous material applicator (1) device and an adaptor device (41) in between the reciprocating mechanism for transmitting the pressing forces of the reciprocating mechanism to the applicator device (1) whilst limiting the downward movements of the reciprocating mechanism to be within acceptable limits, with said adaptor device comprising a pressure receiving member (47) and to be acted upon by one or more pressing members (44) of the reciprocating mechanism of the screen printing machine in a downward direction, and piston displacing means beneath said pressure receiving member (47) which means, in use, is downwardly displaceable together with the pressure receiving member to cause the piston (7) to be displaced downwardly when said pressure receiving member is acted on by said pressing members and to urge solder paste or other viscous material contained within the reservoir downwardly, and one-way movement enabling

Abstract: A support and tensioning frame for a stencil to enable solder paste to be applied to printed circuit boards and other electronic substrates includes a support frame engaged with at least two opposed mounting members. Each mounting member includes at least one projection for engaging an aperture in a stencil to mount the stencil under tension. A permanent-biasing mechanism engages one or more of the mounting members to place the stencil under tension. A second biasing mechanism engages the mounting member to provide a bias opposite that of the permanent-biasing mechanism to facilitate release of a mounted stencil.

Abstract: A support and tensioning frame for a stencil to enable solder paste to be applied to printed circuit boards and other electronic substrates includes a support frame engaged with at least two opposed mounting members. Each mounting member includes at least one projection for engaging an aperture in a stencil to mount the stencil under tension. A permanent-biasing mechanism engages one or more of the mounting members to place the stencil under tension. A second biasing mechanism engages the mounting member to provide a bias opposite that of the permanent-biasing mechanism to facilitate release of a mounted stencil.

Abstract: A stencil and stencil identification system in which the stencil carries a tagging device capable of storing data corresponding to characteristics of the stencil and the pattern of apertures formed in the stencil. The stencil with tagging device may be utilized in combination with a stencil printing device having a tag reader which reads information data stored within the tagging device and/or writes information into the tagging device relating to characteristics of the stencil or other criteria.

Abstract: A contactor comprises first and second armatures which are urged towards contact-making positions by first and second windings, respectively. Each of the armatures displaces the other armature from its contact-making position when moving towards its own contact-making position. A controller actuates each of the windings before deactuating the other of the windings.

Abstract: A support and tensioning frame for a stencil to enable solderi paste to be applied to printed circuit boards and other electronic substrates comprising a support frame having four side members with at least two opposing side members having a stencil support surface which the stencil abuts and over which the stencil is flexed by two displaceable mounting bars disposed within opposing side members. The mounting bars are engaged with the stencil by a plurality of projections extending from a terminal edge of a mounting plate comprising each mounting bar which are sized for receipt by a plurality of apertures disposed along at least two side edges of the stencil. Each mounting bar is biased in an outwardly position by a plurality of compression springs disposed along each side member.

Abstract: A contactor comprises first and second armatures which are urged towards contact-making positions by first and second windings, respectively. Each of the armatures displaces the other armature from its contact-making position when moving towards its own contact-making position. A controller actuates each of the windings before deactuating the other of the windings.

Abstract: A stencil of sheet metal for enabling solder paste to be applied to circuit boards includes a main body portion and opposite side regions which are apertured so as to be more flexible than the main body portion, and so as to enable these opposite side regions to be bent without kinking or other deformation during tensioning. The invention further includes an apparatus for enabling solder paste to be applied to a circuit board by a stenciling process, the apparatus including a stencil as described together with a support therefor, the stencil being attached to the support and being detachable therefrom. The side regions of the stencil are flexed for attachment to the support, so that the interconnection between the support and the stencil does not project beneath a lowermost planar surface of the stencil.

Abstract: An ignition exciter for an engine, comprising a pulse generator for generating output pulses for an igniter plug, and an oscillator for repeatedly triggering the pulse generator at a repetition rate such that each output pulse is produced before ionization caused by a preceding output pulse has substantially disappeared.

Abstract: A machine which has an endless conveyer belt for conveying workpieces past a work station where operations such as, for example, grinding operations are performed on the workpieces. Thus this conveyer belt has upper and lower runs and a support extends between these upper and lower runs and has an upper surface engaging a lower surface of the upper run of the conveyor belt to support this upper run for sliding movement. A part of the upper surface of the support, which engages the lower surface of the upper run of the belt, includes structure for cleaning the conveyor belt at the lower surface of its upper run so as to avoid any possible undesired separation of the upper run of the endless belt from the upper surface of the support.