Patents by Inventor David Gondek

David Gondek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190170729
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed.
    Type: Application
    Filed: August 22, 2018
    Publication date: June 6, 2019
    Inventors: Randolph J. NOELLE, Li-Fan Lu, Sergio Quezada, David Gondek
  • Patent number: 9037452
    Abstract: Systems and method automatically collect training data from manually created semantic relations, automatically extract rules from the training data to produce extracted rules, and automatically characterize existing semantic relations in the training data based on co-occurrence of the extracted rules in the existing semantic relations. Such systems and methods automatically construct semantic relation topics based on the characterization of the existing semantic relations, and group instances of the training data into the semantic relation topics to detect new semantic relations.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: May 19, 2015
    Assignee: AFRL/RIJ
    Inventors: James J. Fan, David Gondek, Aditya A. Kalyanpur, Chang Wang
  • Publication number: 20140004537
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNF.
    Type: Application
    Filed: May 22, 2013
    Publication date: January 2, 2014
    Inventors: Randolph J. Noelle, Li-Fan Lu, Sergio Quezada, David Gondek
  • Publication number: 20130246046
    Abstract: Systems and method automatically collect training data from manually created semantic relations, automatically extract rules from the training data to produce extracted rules, and automatically characterize existing semantic relations in the training data based on co-occurrence of the extracted rules in the existing semantic relations. Such systems and methods automatically construct semantic relation topics based on the characterization of the existing semantic relations, and group instances of the training data into the semantic relation topics to detect new semantic relations.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 19, 2013
    Applicant: International Business Machines Corporation
    Inventors: JAMES J. FAN, David Gondek, Aditya A. Kalyanpur, Chang Wang
  • Patent number: 8465740
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: June 18, 2013
    Assignee: Trustees of Dartmouth College
    Inventors: Randolph J. Noelle, Li-Fan Lu, Sergio Quezada, David Gondek
  • Patent number: 8236304
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: August 7, 2012
    Assignee: Trustees of Dartmouth College
    Inventors: Randolph J. Noelle, Li-Fan Lu, Sergio Quezada, David Gondek
  • Publication number: 20120195894
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNF.
    Type: Application
    Filed: December 15, 2011
    Publication date: August 2, 2012
    Inventors: Randolph J. Noelle, Li-Fan Lu, Sergio Quezada, David Gondek
  • Patent number: 8097249
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: January 17, 2012
    Assignee: Trustees of Dartmouth College
    Inventors: Randolph J. Noelle, Li-Fan Lu, Sergio Quezada, David Gondek
  • Publication number: 20080287358
    Abstract: The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates ?CD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon ?CD3/?GITR stimulation. This protein has been designated Treg-sTNE Proteins, antibodies, activated T cells and methods for using the same are disclosed.
    Type: Application
    Filed: April 24, 2006
    Publication date: November 20, 2008
    Inventors: Randolph J. Noelle, Li-Fan Lu, Sergio Quezada, David Gondek
  • Publication number: 20050069762
    Abstract: A container for a battery includes a top portion having a generally rectangular shape and that is configured for coupling to a cover for the battery. The container also includes a plurality of cell containers extending from the top portion for housing wound cells elements. The cell containers have a generally cylindrical shape and are arranged in an offset configuration. The container also includes a structure extending from the top portion in an area of the top portion not supported by a cell container due to the offset cell container configuration. The structure provides enhanced structural rigidity for the top portion in the area of the top portion not supported by a cell container.
    Type: Application
    Filed: April 28, 2004
    Publication date: March 31, 2005
    Inventors: James Daley, David Gondek, Michael Keagle, Dale Trester, Mark Inkmann, Glenn Andersen
  • Patent number: D466478
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: December 3, 2002
    Assignee: Johnson Controls Technology Company
    Inventors: James J. Bolstad, Mark S. Inkmann, Lisa M. Franklin, David Gondek