Abstract: A method for evaluating deep vein thrombosis (DVT) caused by a blood clot formed in a deep vein of a patient is provided. The method includes receiving, at a computing device in communication with an ultrasound imaging device, an ultrasound signal representative of an ultrasound echo reflected from the blood clot, wherein the ultrasound echo is associated with an ultrasound pulse transmitted by the ultrasound imaging device; determining, by the computing device, an acuteness of the blood clot based on a strength of the ultrasound signal; and outputting, to a display in communication with the computing device, a graphical indication of the determined acuteness. In some embodiments, the method further includes transmitting, by use of the ultrasound imaging device, the ultrasound pulse into the deep vein where the blood clot is positioned.

Abstract: A method for evaluating deep vein thrombosis (DVT) caused by a blood clot formed in a deep vein of a patient is provided. The method includes receiving, at a computing device in communication with an ultrasound imaging device, an ultrasound signal representative of an ultrasound echo reflected from the blood clot, wherein the ultrasound echo is associated with an ultrasound pulse transmitted by the ultrasound imaging device; determining, by the computing device, an acuteness of the blood clot based on a strength of the ultrasound signal; and outputting, to a display in communication with the computing device, a graphical indication of the determined acuteness. In some embodiments, the method further includes transmitting, by use of the ultrasound imaging device, the ultrasound pulse into the deep vein where the blood clot is positioned.

Abstract: Example embodiments relate to a computer-implemented method for attributing different system outcomes to one or more of binary input characteristic(s), sizing input characteristic(s), and/or sub-characteristics thereof. For example, a system output may be based on a plurality of interrelated input characteristics. Systems and methods of the present disclosure can provide for disambiguation and tracing of causal chains from input to output, as well as other performance analyses. In some embodiments, performance of a first set of inputs can be compared relative to performance of a reference set of inputs based at least in part on generating a research set of inputs. The research set can include simulated inputs weighted to a neutral position with respect to the reference set.

Abstract: Intravascular ultrasound (IVUS) imaging devices, systems, and method are provided. In one embodiment, an IVUS imaging device includes a flexible elongate member configured to be positioned within a lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion; and an imaging assembly disposed at the distal portion of the flexible elongate member. The imaging assembly includes a first ultrasound transducer operating at a first center frequency; and a second ultrasound transducer operating at a second center frequency different from the first center frequency.

Abstract: An imaging system includes a detector configured to obtain radiation data from one or more sources and a controller. The controller is configured to define plurality of buffers based on at least one initial condition. The radiation data includes a plurality of events. The controller is configured to receive an individual event of the plurality of events and determine if the individual event falls within a designated current buffer. Each of the plurality of events in the current buffer is corrected for pose and aligned in a common two-dimensional space. The plurality of events in the current buffer are reconstructed into a three-dimensional space, the reconstruction being done once for each of the plurality of buffers. The controller is configured to create a three-dimensional image based in part on the reconstruction in the three-dimensional space.

Abstract: An imaging system includes a detector configured to obtain radiation data from one or more sources and a controller. The controller is configured to define plurality of buffers based on at least one initial condition. The radiation data includes a plurality of events. The controller is configured to receive an individual event of the plurality of events and determine if the individual event falls within a designated current buffer. Each of the plurality of events in the current buffer is corrected for pose and aligned in a common two-dimensional space. The plurality of events in the current buffer are reconstructed into a three-dimensional space, the reconstruction being done once for each of the plurality of buffers. The controller is configured to create a three-dimensional image based in part on the reconstruction in the three-dimensional space.

Abstract: Embolism treatment devices, systems, and methods are provided. In one embodiment, an embolism treatment system includes a flexible elongate member configured to be positioned within a blood vessel of a patient, the flexible elongate member comprising a distal portion and a proximal portion; an ultrasound imaging component positioned at the distal portion and configured to emit ultrasound energy towards a blood clot within the blood vessel and collect an image signal representative of the blood clot; a treatment component positioned at the distal portion and configured to treat the blood clot; and a flow sensing component positioned at the distal portion and configured to determine a blood flow measurement within the blood vessel associated with the blood clot.

Abstract: A method for evaluating deep vein thrombosis (DVT) caused by a blood clot formed in a deep vein of a patient is provided. The method includes receiving, at a computing device in communication with an ultrasound imaging device, an ultrasound signal representative of an ultrasound echo reflected from the blood clot, wherein the ultrasound echo is associated with an ultrasound pulse transmitted by the ultrasound imaging device; determining, by the computing device, an acuteness of the blood clot based on a strength of the ultrasound signal; and outputting, to a display in communication with the computing device, a graphical indication of the determined acuteness. In some embodiments, the method further includes transmitting, by use of the ultrasound imaging device, the ultrasound pulse into the deep vein where the blood clot is positioned.

Abstract: A Reflux Rinsing method for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. Feed material having tetrahydrocannabinol (THC) is inserted into a reaction vessel having walls, and upper portion, and a lower portion with a bottom surface. The feed material is exposed to a hydrocarbon liquid in the reaction vessel in a quantity sufficient to keep liquid present in equilibrium with gas in the reaction vessel through the recrystallization process, forming a raw extract having THC. The walls and bottom surface of the reaction vessel are coated with raw extract. The reaction vessel is heated and then the heating is discontinued. Vapor/thin-film DER is promoted in the reaction vessel for a predetermined length of time with no solvent reflux, resulting in formation of purified crystals of THC acid under pressure. The hydrocarbon solvent is reclaimed from the reaction vessel, leaving the purified crystals and impurities.

Abstract: Intravascular ultrasound (IVUS) imaging devices, systems, and method are provided. In one embodiment, an IVUS imaging device includes a flexible elongate member configured to be positioned within a lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion; and an imaging assembly disposed at the distal portion of the flexible elongate member. The imaging assembly includes a first ultrasound transducer operating at a first center frequency; and a second ultrasound transducer operating at a second center frequency different from the first center frequency.

Abstract: Embolism treatment devices, systems, and methods are provided. In one embodiment, an embolism treatment system includes a flexible elongate member configured to be positioned within a blood vessel of a patient, the flexible elongate member comprising a distal portion and a proximal portion; an ultrasound imaging component positioned at the distal portion and configured to emit ultrasound energy towards a blood clot within the blood vessel and collect an image signal representative of the blood clot; a treatment component positioned at the distal portion and configured to treat the blood clot; and a flow sensing component positioned at the distal portion and configured to determine a blood flow measurement within the blood vessel associated with the blood clot.

Abstract: The invention generally relates to systems for imaging and monitoring endoluminal valve formation. In certain aspects, a system of the invention includes: an elongate body defining a lumen and an exit port located on a side of the elongate body, wherein the side of the elongate body is configured to engage with a vessel wall; a tissue dissection probe disposed within the lumen, and configured to extend out of the exit port and into the vessel wall in order to form an intramural space in the vessel wall; and an imaging element located on the tissue dissection probe.

Abstract: The present invention generally relates to methods for assessing the completeness of a varicose vein ablation. The method involves the use of imaging and/or functional measurement data to determine the extent to which a varicose vein has closed as a result of an ablation procedure.

Abstract: The present invention generally relates to methods for detecting endoleaks associated with EVAR procedures using physiological measurements. The method can involve the taking of functional measurement data in the vicinity of a stent-graft delivered as part of the EVAR procedure and determining the presence of an endoleak based on such data.

Abstract: The invention generally relates to devices and methods for imaging and delivering a fertilized egg into a woman's uterus. In certain embodiments, the invention provides devices that include a body configured to fit within a lumen of a woman's reproductive system. The body includes an opening. Devices of the invention also include a channel within the body. The channel includes a distal end that is connected to the opening. Devices of the invention also include an imaging assembly coupled to the body.

Abstract: The invention provides an intravascular catheter with an expandable member such as a balloon with an imaging device on a surface of the expandable member. The imaging device can use an optical fiber on a surface of the expandable member to image a treatment site. Since an image can be captured directly from the surface of the expandable member, an operator can examine the treatment site while positioning the expandable member. With the treatment site in view, the operator can deliver the treatment (e.g., inflate the balloon or deploy the stent) with confidence that it will be located properly.

Abstract: The invention generally relates to devices and methods that allow an operator to obtain real-time images of a luminal surface during an implant delivery procedure. In certain embodiments, a delivery device of the invention includes an elongate body and an inner member moveably disposed within the elongate body. The elongate body includes a first imaging element and defining a center lumen that leads to an opening. The elongate body is configured to releasably hold an implant within the center lumen and the first imaging element is configured to at least partially surround the center lumen such that the implant is deployable through the first imaging element. The inner member is configured to engage with and deploy the implant out of the opening of the elongate body and into a body lumen.

Abstract: A cooking oil container has a filter cup retained at the upper end thereof. The filter cup retains a planar circular filter at the lower end and a seal between the filter holder and the bottom of the filter cup prevents oil from overflowing around the circumference of the filter holder to avoid the filter. The filter cup is spaced from the inner walls of the container to allow air to escape from the bottom of the container. The top of the container has a grip ring and the inverted top is useable as a drip tray for the filter cup while oil is being poured out of the container.

Abstract: A cooking oil container has a filter cup retained at the upper end thereof. The filter cup retains a planar circular filter at the lower end and a seal between the filter holder and the bottom of the filter cup prevents oil from overflowing around the circumference of the filter holder to avoid the filter. The filter cup is spaced from the inner walls of the container to allow air to escape from the bottom of the container. The top of the container has a grip ring and the inverted top is useable as a drip tray for the filter cup while oil is being poured out of the container.