Abstract: An attachment device for releasably attaching a fluid line to a fluid inlet or outlet is disclosed. The device comprises an attachment member for releasably engaging a fluid inlet or outlet, and an elastic member coupled to the attachment member. The attachment device is attachable to a fluid line such that the attachment member is moveable relative to the fluid line and such that movement of the attachment member relative to the fluid line causes elastic deformation of the elastic member.

Abstract: A miniature mass spectrometer is disclosed comprising an atmospheric pressure ionization source, a first vacuum chamber having an atmospheric pressure sampling orifice or capillary, a second vacuum chamber located downstream of the first vacuum chamber and a third vacuum chamber located downstream of the second vacuum chamber. A first vacuum pump is arranged and adapted to pump the first vacuum chamber, wherein the first vacuum pump is arranged and adapted to maintain the first vacuum chamber at a pressure <10 mbar. A first RF ion guide is located within the first vacuum chamber and an ion detector is located in the third vacuum chamber. The ion path length from the atmospheric pressure sampling orifice or capillary to an ion detecting surface of the ion detector is ?400 mm.

Abstract: Disclosed herein is an ion guide comprising a plurality of axially stacked plates, wherein at least some or all of said plates comprise: a first electrically conductive portion; and a second electrically conductive portion, wherein the second electrically conductive portion is electrically isolated from the first electrically conductive portion, the first and second electrically conductive portions being shaped and arranged relative to each other so as to define an opening through which ions are axially transmitted in use; wherein, in use, a first AC or RF voltage is applied to the first electrically conductive portion and a second AC or RF voltage is applied to the second electrically conductive portion in order to confine ions radially within said opening. The first and second electrically conductive portions (1, 2) may be separately formed and interleaved within the ion guide to define the plates.

Abstract: The present invention generally relates to methods and device for treatment of spinal deformity, wherein at least one tether is utilized to maintain the distance between the spine and the an ilium to (1) prevent increase in abnormal spinal curvature, (2) slow progression of abnormal curvature, or (3) impose at least one corrective displacement and/or rotation.

Abstract: Determining a location for a non-access point device based on non-access point device emulation of an access point (AP) device is disclosed. A non-AP device can pass itself off as an actual AP device to piggyback of location reporting by user equipment (UE). Where a UE observes an emulated AP, e.g., a non-AP device masquerading as an AP device, the observance of the emulated AP can be reported, along with UE location information captured at the time of the observance, to a network database. The UE location information can be used to determine a location of the emulated AP. The location of the emulated AP can be retrieved from the database in response to a query identifying the emulated AP. This can enable the non-AP device to query its own location as observed by the UE. This can enable other devices to receive the location of the non-AP device.

Abstract: An atherectomy system includes a handle and a drive motor that is adapted to rotate a drive cable extending through the handle and operably coupled to an atherectomy burr. A control system is adapted to regulate operation of the drive motor, including providing the drive motor with a high frequency pulse width modulation (PWM) drive signal in order to operate the drive motor. The control system monitors a motor performance parameter such as motor speed or motor torque, and when the motor performance parameter approaches a limit of a performance range, the control system adds a low frequency PWM signal to the high frequency PWM drive signal, thereby causing the drive motor to produce a tactile signal that signals to the user that the motor performance parameter is approaching the limit of the performance range.

Abstract: An atherectomy system includes a drive mechanism adapted to rotatably actuate an atherectomy burr and a control system that is adapted to regulate operation of the drive mechanism. The drive mechanism may include a drive cable that is coupled with the atherectomy burr and a drive motor that is adapted to rotate the drive cable. The control system includes a drive module adapted to provide an operational signal to operate the drive mechanism, a monitoring module adapted to monitor operation of the drive mechanism and to determine if the drive mechanism is operating within a predetermined range and an excitation module that is operably coupled to the drive mechanism and is adapted to provide haptic feedback to a user of the drive mechanism if the monitoring module determines that the drive mechanism is not operating within a predetermined range.

Abstract: Devices, systems and methods for use in spinal surgeries. The system may include a fastener system comprising a fastener, a staple, and a locking cap. A cord may extend along the spine and through at least one fastener system. An instrument may be provided for tensioning the cord. The system may, for example, apply fixation on the convexity of the scoliotic vertebrae to limit growth on the convex side and allow unilateral growth on the concave side.

Abstract: An atherectomy system includes a drive mechanism that is adapted to rotatably actuate an atherectomy burr and a controller that is adapted to regulate operation of the drive mechanism. In some cases, the drive mechanism includes a drive cable that is coupled with the atherectomy burr and a drive motor that is adapted to rotate the drive cable. The controller is adapted to receive an indication of an increase in torque experienced at the atherectomy burr and is further adapted to, in response, regulate operation of the drive mechanism such that the increase in torque results in a noticeable reduction in speed of the drive mechanism such that a user of the atherectomy system notices the reduction in speed and is alerted to the increase in torque.

Abstract: Medical devices and methods for using medical devices are disclosed. A rotational atherectomy device may include an elongate drive coil having a proximal end region and a distal end region, the elongate drive coil having a coil winding extending in a first helical direction, the elongate drive coil having a coil pitch. A tubular member is welded to the distal end region of the elongate drive coil via one or more helical welds that extend helically at least part way around the tubular member and a cutting member welded to the tubular member.

Abstract: A mass spectrometer is disclosed comprising an atmospheric pressure interface comprising a gas cone 6 having an inlet aperture, wherein the gas cone 6 has a first longitudinal axis arranged along an x-axis and an Electrospray ion source comprising a first capillary tube 2 having an outlet and having a second longitudinal axis and a second capillary tube 3 which surrounds the first capillary tube 2. The mass spectrometer further comprises a desolvation gas supply tube and a first device arranged and adapted to supply an analyte liquid via the first capillary tube 2 so that the liquid exits the outlet of the first capillary tube 2 at a flow rate >200 ?L/min.

Abstract: An ion guide comprises a first ion guide portion that forms a first ion guiding path and a second ion guide portion that forms a second ion guiding path. A first device applies a plurality of different first voltages or potentials to the electrodes of the first ion guide portion in order to generate an electric field that directs ions from the first ion guiding path of the first ion guide portion into the second ion guiding path of the second ion guide portion. The use of plural different first voltages can provide a controlled transfer of ions from the first ion guiding path into the second ion guiding path.

Abstract: A top locking rotatable suture anchor device secures one or more sutures with the suture anchor device, installed within a bone at a surgical treatment site, providing rotation of the suture while secured within the suture anchor device and providing adjustment to the tension of the suture during the surgical procedure, the suture anchor device including a delivery tool cooperating with the suture device to conduct the installation of the suture anchor device and tensioning of the suture within suture anchor device.

Abstract: Chimeric proteins are expressed, secreted or released by a bacterium to immunize against or treat a parasite, infectious disease or malignancy. The delivery vector may also be attenuated, non-pathogenic, low pathogenic, or a probiotic bacterium. The chimeric proteins include chimeras of, e.g., phage coat and/or colicin proteins, bacterial toxins and/or enzymes, autotransporter peptides, lytic peptides, multimerization domains, and/or membrane transducing (ferry) peptides. The active portion of the immunogenic chimeric proteins can include antigens against a wide range of parasites and infectious agents, cancers, Alzheimer's and Huntington's diseases, and have enhanced activity when secreted or released by the bacteria, and/or have direct anti-parasite or infectious agent activity. The activity of the secreted proteins is further increased by co-expression of a protease inhibitor that prevents degradation of the effector peptides.

Abstract: A radio tag comprising a first radio and a second radio and a method for providing a communications service are disclosed. For example, the method comprises entering, by a processor of the radio tag, an active state of the radio tag and activating the second radio when a wake-up signal is received, where the second radio draws power from a power source, transmitting, by the processor of the radio tag, data to a device or receiving the data from the device when the radio tag is in the active state, and deactivating, by the processor of the radio tag, the second radio and entering an idle state when the wake-up signal is no longer being received, where only the first radio draws power from the power source for listening for the wake-up signal in the idle state.

Abstract: An exercise device featuring a pair of knee joints, each pivotally and respectively coupled to a pair of calf linkages, each of the pair of calf linkages having a foot pedal at an opposite lower end that supports low impact user-defined natural exercise gait patterns. The knee joints are supported and directed to travel by linkage and/or carriage systems that operate substantially below a user hip area and direct the knee joints in a variety of travel paths, ranging from a constant arc, a linear pathway, to a variety of irregular arc shaped paths to pathways that may change during use. A secondary system coupled to the linkage and/or carriage systems provides lift and dampening forces to influence a responsiveness of the foot pedals via bending and straightening of the calf linkage about the respective knee joint, yet does not restrict back and forth travel of the respective knee joint.

Abstract: A miniature mass spectrometer is disclosed comprising an atmospheric pressure ionization source 701, a first vacuum chamber having an atmospheric pressure sampling orifice or capillary, a second vacuum chamber located downstream of the first vacuum chamber and a third vacuum chamber located downstream of the second vacuum chamber. A first vacuum pump 707 is arranged and adapted to pump the first vacuum chamber, wherein the first vacuum pump 707 is arranged and adapted to maintain the first vacuum chamber at a pressure <10 mbar. A first RF ion guide 702 is located within the first vacuum chamber. An ion detector 705 is located in the third vacuum chamber. The ion path length from the atmospheric pressure sampling orifice or capillary to an ion detecting surface of the ion detector 705 is ?400 mm.

Abstract: An implantable growing rod assembly adapted to be secured along a length of a spine for treating deformities of the spine. The assembly includes a housing, a fixed rod extending along a longitudinal axis away from the housing, and an expansion rod extendible from the housing along the longitudinal axis. A driver assembly is fixed to the housing and adapted to translate the expansion rod along the longitudinal axis.

Abstract: Medical systems and methods for making and using medical systems are disclosed. Example medical systems may include an atherectomy system configured to engage and remove plaque from walls in vessels of a vascular system. The atherectomy system may include a drive shaft, a rotational tip coupled to an end of the drive shaft, a motor coupled to the drive shaft to rotate the rotational tip, and a controller configured to control a motor state of the motor. The controller may adjust a range of possible load outputs from the motor and/or a maximum load output from the motor to account for external loads acting on the drive shaft and/or rotational tip rotated by the motor and facilitate passing an occlusion in a vasculature of a patient.

Abstract: Determining a location for a non-access point device based on non-access point device emulation of an access point (AP) device is disclosed. A non-AP device can pass itself off as an actual AP device to piggyback of location reporting by user equipment (UE). Where a UE observes an emulated AP, e.g., a non-AP device masquerading as an AP device, the observance of the emulated AP can be reported, along with UE location information captured at the time of the observance, to a network database. The UE location information can be used to determine a location of the emulated AP. The location of the emulated AP can be retrieved from the database in response to a query identifying the emulated AP. This can enable the non-AP device to query its own location as observed by the UE. This can enable other devices to receive the location of the non-AP device.