Abstract: An altered antibody chain is produced in which the CDR's of the variable domain of the chain are derived from a first mammalian species. The framework-encoding regions of DNA encoding the variable domain of the first species are mutated so that the mutated framework-encoding regions encode a framework derived from a second different mammalian species. The or each constant domain of the antibody chain, if present, are also derived from the second mammalian species.

Abstract: A hydrogen storage unit which uses hydrogen storage alloys to store hydrogen, and more particularly a heat transfer management/compartmentalization system for use in such system. The hydrogen storage alloy may be divided into compartments, separated by discs, further divided into sub-compartments by a flapper wheel. The discs and flapper wheel provide for optimal heat transfer throughout the system. The compartmentalization of the vessel may prevent compaction of the hydrogen storage alloys, which could lead to excessive strain on the vessel causing damage, deformation, or rupture of the vessel.

Abstract: A hydrogen storage unit which uses hydrogen storage alloys to store hydrogen, and more particularly a heat transfer management/compartmentalization system for use in such system. The hydrogen storage alloy may be divided into compartments, separated by discs, further divided into sub-compartments by a flapper wheel. The discs and flapper wheel provide for optimal heat transfer throughout the system. The compartmentalization of the vessel may prevent compaction of the hydrogen storage alloys, which could lead to excessive strain on the vessel causing damage, deformation, or rupture of the vessel.

Abstract: An antibody or antibody fragment with a binding affinity for the CD3 antigen, having a human constant region, and human or rat variable framework region, a heavy chain with CDRs having the amino acid sequences:(a) Ser-Phe-Pro-Met-Ala (SEQ ID NO:1),(b) Thr-Ile-Ser-The-Ser-Gly-Gly-Arg-Thr-Tyr-Tyr-Arg-Asp-Ser-Val-Lys-Gly (SEQ ID NO:2),(c) Phe-Arg-Gln-Tyr-Ser-Gly-Gly-Phe-Asp-Tyr (SEQ ID NO:3),and light chain with CDRs having the amino acid sequences:(d) Thr-Leu-Ser-Ser-Gly-Asn-Ile-Glu-Asn-Tyr-Val-His (SEQ ID NO:4),(e) Asp-Asp-Asp-Lys-Arg-Pro-Asp (SEQ ID NO:5),(f) His-Ser-Tyr-Val-Ser-Ser-Phe-Asn-Val (SEQ ID NO:6),in which the heavy chain CDRs are arranged in the order (a), (b), (c) in the leader.fwdarw.constant region direction and the light chain CDRs are arranged in the order (d), (e), (f) in the leader.fwdarw.constant region direction.