Patents by Inventor David Grampovnik

David Grampovnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aryl and arylalkyl substituted pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
    Patent number: 9464082
    Abstract: The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein R1, R2, R3, R4, R5, R6, m, n, X and Y are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use for the treatment and prevention of diseases such as those associated with oxidative stress and inflammation.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: October 11, 2016
    Assignees: AbbVie Inc., Reata Pharmaceuticals, Inc.
    Inventors: Pamela Donner, Rolf Wagner, Jason Shanley, Howard Heyman, Allan Krueger, Hui-Ju Chen, Michael Rozema, David Grampovnik, Melean Visnick, Eric Anderson, Xin Jiang, Christopher F. Bender, Gary Louis Bolton, Bradley William Caprathe, Chitase Lee, William Howard Roark
  • ARYL AND ARYLALKYL SUBSTITUTED PYRAZOLYL AND PYRIMIDINYL TRICYCLIC ENONES AS ANTIOXIDANT INFLAMMATION MODULATORS
    Publication number: 20150225397
    Abstract: The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein R1, R2, R3, R4, R5, R6, m, n, X and Y are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use for the treatment and prevention of diseases such as those associated with oxidative stress and inflammation.
    Type: Application
    Filed: January 23, 2015
    Publication date: August 13, 2015
    Inventors: Pamela Donner, Rolf Wagner, Jason Shanley, Howard Heyman, Allan Krueger, Hui-Ju Chen, Michael Rozema, David Grampovnik, Melean Visnick, Eric Anderson, Xin Jiang, Christopher F. Bender, Gary Louis Bolton, Bradley William Caprathe, Chitase Lee, William Howard Roark
  • Prodrugs of HIV protease inhibitors
    Publication number: 20070270383
    Abstract: A compound of the formula is disclosed as a prodrug of an HIV protease inhibitor. Methods and compositions for inhibiting HIV protease activity and treating HIV infection are also disclosed.
    Type: Application
    Filed: June 29, 2005
    Publication date: November 22, 2007
    Inventors: David DeGoey, William Flosi, David Grampovnik, Larry Klein, Dale Kempf, Xiu Wang
  • ANTI-VIRAL COMPOUNDS
    Publication number: 20070232627
    Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
    Type: Application
    Filed: December 20, 2006
    Publication date: October 4, 2007
    Inventors: David Betebenner, David DeGoey, Clarence Maring, Allan Krueger, Nobuhiko Iwasaki, Todd Rockway, Curt Cooper, David Anderson, Pamela Donner, Brian Green, Dale Kempf, Dachun Liu, Keith McDaniel, Darold Madigan, Christopher Motter, John Pratt, Jason Shanley, Michael Tufano, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami Pilot-Matias, Sherie Masse, Robert Carrick, Wenping He, Liangjun Lu, David Grampovnik
  • ANTI-VIRAL COMPOUNDS
    Publication number: 20070197558
    Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
    Type: Application
    Filed: December 20, 2006
    Publication date: August 23, 2007
    Inventors: David Betebenner, David DeGoey, Clarence Maring, Allan Krueger, Nobuhiko Iwasaki, Todd Rockway, Curt Cooper, David Anderson, Pamela Donner, Brian Green, Dale Kempf, Dachun Liu, Keith McDaniel, Darold Madigan, Christopher Motter, John Pratt, Jason Shanley, Michael Tufano, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami Pilot-Matias, Sherie Masse, Robert Carrick, Wenping He, Liangjun Lu, David Grampovnik
  • HIV protease inhibiting compounds
    Publication number: 20050159469
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 10, 2004
    Publication date: July 21, 2005
    Inventors: John Randolph, Hui-Ju Chen, David DeGoey, Charles Flentge, William Flosi, David Grampovnik, Peggy Huang, Douglas Hutchinson, Dale Kempf, Larry Klein, Ming Yeung
  • HIV protease inhibiting compounds
    Publication number: 20050148623
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 9, 2004
    Publication date: July 7, 2005
    Inventors: David DeGoey, Charles Flentge, William Flosi, David Grampovnik, Dale Kempf, Larry Klein, Ming Yeung, John Randolph, Xiu Wang, Su Yu
  • HIV protease inhibiting compounds
    Publication number: 20050131017
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 11, 2003
    Publication date: June 16, 2005
    Inventors: David DeGoey, Charles Flentge, William Flosi, David Grampovnik, Dale Kempf, Larry Klein
  • HIV protease inhibiting compounds
    Publication number: 20050131042
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 11, 2003
    Publication date: June 16, 2005
    Inventors: Charles Flentge, Hui-Ju Chen, David DeGoey, William Flosi, David Grampovnik, Peggy Huang, Dale Kempf, Larry Klein, Allan Krueger, Darold Madigan, John Randolph, Minghua Sun, Ming Yeung, Chen Zhao