Abstract: Systems and methods for detecting and monitoring human breathing, respiration, and heart rate using statistics about the wireless channel between two or more connected devices. A user is monitored for identifying patterns in the uses behavior that may allow the system to alert a caregiver to deviations in the user behavior that may be indicative of a potential issue, such as depression. A presence may be further detected in a sensing area through the detection of spectral components in the breathing frequency range of comprises user includes transforming phase difference between spatial streams and amplitude of the samples representing frequency response of the channel for any frequency value into frequency domain to perform frequency analysis. Statistical analysis may be performed on the frequency space provided by the transformation. Micro motions may also be detected by detecting presence in a sensing area through the detection of spectral components in the micro motion frequency range.

Abstract: The invention concerns improvements in needle-free devices for delivery of therapeutic and/or prophylactic agents, such as solid dose drugs, including vaccines. The needle-free device disclosed herein comprises novel structural arrangements and modes of actuation and operation, resulting in enhanced functionality and benefits to the user and/or patient.

Abstract: The invention relates to a single-use cassette assembly for use in a reusable solid dose formulation delivery actuator device. Such improvements permit delivery of at least one therapeutic or prophylactic compound, or a solid dose formulation including, for example, a vaccine comprising the same with improved safety and reliability. The invention further concerns an improved needle-free method for delivering at least one therapeutic compound or a formulation comprising the same.

Abstract: The invention concerns improvements in needle-free devices for delivery of therapeutic and/or prophylactic agents, such as solid dose drugs, including vaccines. The needle-free device disclosed herein comprises novel structural arrangements and modes of actuation and operation, resulting in enhanced functionality and benefits to the user and/or patient.

Abstract: The present disclosure describes a treatment composition comprising a nanoparticle composition comprising nanoparticles functionalized with surface amine groups and a crosslinking composition comprising genipin. The disclosure also describes a kit comprising the treatment composition, and instructions for using the kit to crosslink the nanoparticles to a tissue graft. The treatment composition and kit can be used to crosslink nanoparticles to a tissue graft, and the resulting tissue graft can be used to replace defective tissue in a subject in need thereof.

Abstract: The present disclosure provides collagen bioink compositions and chemically uncrosslinked and crosslinked collagen structures including collagen microparticles and scaffolds. Also provided are methods of their fabrication and use. Applications for using these collagen structures include treatments of damaged tissue, particularly those caused by osteoarthritis.

Abstract: An inflatable stent for use in the repair and maintenance of pipes such as water or gas supply pipes, or for use as a medical device comprises an inflatable portion having an inner and outer membrane. When inflated, the inner and outer membranes are radially spaced apart to define an annular space there between. The inner membrane defines a passage between a first and second end and the outer membrane defines a first diameter (D1) of the stent. The inner and outer membranes are connected by a plurality of connecting members in the annular space. End caps are disposed on the first and second ends of the stent which connect the inner and outer membranes. The inflatable portion further comprises an inflatable pipe or lumen engaging portion that defines a second, larger diameter (D2) of the stent, when inflated.

Abstract: A downhole apparatus comprises a tubular body having first and second ports in a wall thereof and a first valve arrangement associated with the first port. The downhole apparatus includes a second valve arrangement associated with the second port and a sand control element operable to move between a first deactivated state to a second activated state, wherein the sand control element is in fluid communication with the first port of the tubular body.

Abstract: Retrieve a service address from a database of an internet service provider. Obtain a corresponding geographic location from a geographic information system server based on the service address. Associate a transceiver device with the geographic location. The transceiver device is configurable to operate in a standard power mode and a low power mode having a lower power than the standard power mode. Make the geographic location available, over a network, to a database containing locations of active incumbent devices. Obtaining, from the database, approval for the transceiver device to operate in the standard power mode, based on the geographic location and the locations of the active incumbent devices. Operate the transceiver device in the standard power mode, responsive to obtaining the approval.

Abstract: A method of operating a valve arrangement of a downhole apparatus comprising a tubular body having first and second ports in a wall thereof includes operating the valve arrangement from a locked first configuration, in which the first port is closed and the second port is closed, to a locked second configuration, in which the first port is open and the second port is closed, wherein the locked first configuration is an initial configuration of the valve arrangement. The method includes operating the valve arrangement from tile locked second configuration to a third configuration, in which the first port is closed and the second port is open.

Abstract: A method of operating a valve arrangement of a downhole apparatus (that includes a tubular body having first and second ports in a wall thereof) comprising operating the valve arrangement from a locked first configuration, in which the first port is closed and the second port is closed, to a locked second configuration, in which the first port is open and the second port is closed, wherein the valve arrangement includes a valve member including a first port, the first port associated with the first port of the tubular body, and a second port associated with the second port of the tubular body, wherein the valve arrangement comprises a further retaining member. The method includes operating the valve arrangement from the locked second configuration to a third configuration, in which the first port is closed and the second port is open.

Abstract: A valve arrangement is for a downhole apparatus having a tubular body having first and second ports in a wall thereof. The valve arrangement being configurable to be locked in a first configuration with the tubular body, such that the first port is closed and the second port is closed; configurable to be locked in a second configuration with the tubular body, such that the first port is open and the second port is closed; and configurable to be locked in a third configuration with the tubular body, such that the first port is closed and the second port is open.

Abstract: A wireless motion detection system is provided which uses a sharp band-stop and low-pass filters to reject unwanted low and high frequency components of a signal in the CSI. A gap in the frequency domain is caused by taking the absolute value of the signal when using the absolute value of channel matrix Hv for motion detection. A sharp band-stop (notch) filter is used to reject any unwanted signals that have significant components in this gap. A low-pass filter is used to reject all unwanted signal after the motion highest frequency.

Abstract: A valve arrangement is for a downhole apparatus having a tubular body having first and second ports in a wall thereof. The valve arrangement being configurable to be locked in a first configuration with the tubular body, such that the first port is closed and the second port is closed; configurable to be locked in a second configuration with the tubular body, such that the first port is open and the second port is closed; and configurable to be locked in a third configuration with the tubular body, such that the first port is closed and the second port is open.

Abstract: Technologies for attestation techniques, systems, and methods for determining an individual's movement are provided. The individual's movement is determined by passive indoor positioning technology using channel state information (CSI). A first set of data associated with an impulse or frequency response determined using channel state information (CSI) may be received from a Wireless access point located in proximity to a monitored space. A second set of data may also be received from an Internet of Things (IoT) device located in proximity to the monitored space. The first set of data may be compared to the second set of data. A profile database may be updated to replace the first set of data with the second set of data when the first and second sets of data are different.

Abstract: Systems and methods for tracking activities of daily living (ADL) of a user are provided. The method monitors data from one or more internet of things (IoT) devices corresponding to one or more ADLs. The method further monitors data from an activity identification module. The data received is related to an ADL and includes one or more steps specific to the ADL. The data related to the ADL is stored in an activity logging database located in a memory and compared to an activity best practices (BP) database. A score that represents a compliance level is calculated based on the compared data. A response that corresponds the compliance level from a response database is executed.

Abstract: A valve arrangement is for a downhole apparatus having a tubular body having first and second ports in a wall thereof. The valve arrangement comprises a valve member that comprises a first port associated with the first port of the tubular body; and a second port associated with the second port of the tubular body. The valve arrangement is configurable to be locked in a first configuration with the tubular body, such that the first port is closed and the second port is closed. The valve arrangement is configurable to be locked in a second configuration with the tubular body, such that the first port is open and the second port is closed. The valve arrangement is configurable to be locked in a third configuration with the tubular body, such that the first port is closed and the second port is open.

Abstract: A valve arrangement is for a downhole apparatus having a tubular body having first and second ports in a wall thereof. The valve arrangement comprises a first valve arrangement comprising a first valve member associated with the first port of the tubular body; and a second valve arrangement comprising a second valve member associated with the second port of the tubular body. The first valve arrangement and the second valve arrangement are configurable to lock in a first configuration with the tubular body, such that the first port is closed and the second port is closed; to lock in a second configuration with the tubular body, such that the first port is open and the second port is closed; and to lock in a third configuration with the tubular body, such that the first port is closed and the second port is open.

Abstract: Systems and methods for detecting and monitoring human breathing, respiration, and heart rate using statistics about the wireless channel between two or more connected devices. A user is monitored for identifying patterns in the uses behavior that may allow the system to alert a caregiver to deviations in the user behavior that may be indicative of a potential issue, such as depression. A presence may be further detected in a sensing area through the detection of spectral components in the breathing frequency range of comprises user includes transforming phase difference between spatial streams and amplitude of the samples representing frequency response of the channel for any frequency value into frequency domain to perform frequency analysis. Statistical analysis may be performed on the frequency space provided by the transformation. Micro motions may also be detected by detecting presence in a sensing area through the detection of spectral components in the micro motion frequency range.

Abstract: A method comprising operating a first valve arrangement and a second valve arrangement from a locked first configuration, in which the first port is closed and the second port is closed, to a locked second configuration, in which the first port is open and the second port is closed, wherein the first valve arrangement comprises one or more locking devices configured to lock a first valve member of the first valve arrangement in place relative to the tubular body. The method comprising operating the first valve arrangement and the second valve arrangement from the locked second configuration to a third configuration, in which the first port is closed and the second port is open.