Patents by Inventor David Grewe
David Grewe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8637109Abstract: The disclosure relates to a method for coating a target. The method includes providing a target and an electrospinning apparatus. The target comprises a first surface and an opposing second surface. The electrospinning apparatus comprises a mandrel, a mask including an aperture, a reservoir loaded with a solution, and an orifice fluidly coupled to the reservoir. The mandrel is located adjacent the target second surface. The orifice is located at a distance from the target first surface. The mask is located intermediate the orifice and the target first surface. The solution is electrospun through the mask aperture onto the target first surface. In one example the target is an endoluminal prosthesis.Type: GrantFiled: December 2, 2010Date of Patent: January 28, 2014Assignee: Cook Medical Technologies LLCInventors: David Grewe, Blayne Roeder, Steven Charlebois, Adam Griebel
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Patent number: 8454673Abstract: A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port.Type: GrantFiled: October 18, 2010Date of Patent: June 4, 2013Assignee: Cordis CorporationInventors: Laila Al-Marashi, David Grewe, Stephen Griffin, Elaine Lim, David Majercak, Roger Stevens
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Publication number: 20110135806Abstract: The disclosure relates to a method for coating a target. The method includes providing a target and an electrospinning apparatus. The target comprises a first surface and an opposing second surface. The electrospinning apparatus comprises a mandrel, a mask including an aperture, a reservoir loaded with a solution, and an orifice fluidly coupled to the reservoir. The mandrel is located adjacent the target second surface. The orifice is located at a distance from the target first surface. The mask is located intermediate the orifice and the target first surface. The solution is electrospun through the mask aperture onto the target first surface. In one example the target is an endoluminal prosthesis.Type: ApplicationFiled: December 2, 2010Publication date: June 9, 2011Inventors: David Grewe, Blayne Roeder, Steven Charlebois, Adam Griebel
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Publication number: 20110034989Abstract: A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port.Type: ApplicationFiled: October 18, 2010Publication date: February 10, 2011Applicant: Cordis CorporationInventors: Laila Al-Marashi, David Grewe, Stephen Griffin, Elaine Lim, David Majercak, Roger Stevens
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Patent number: 7815600Abstract: A rapid-exchange balloon catheter or stent delivery system, for medically treating a patient, has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near the proximal leg of the balloon. An inner tubular body defines a guidewire lumen and extends from a distal guidewire port at the catheter distal end to proximal guidewire port located between the balloon and the proximal hub. The hypotube has an aperture for accepting the inner body proximal end and a circumferential cut pattern. The cut pattern adds flexibility and may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The proximal guidewire port may be positioned on or in between the individual portions of the cut pattern.Type: GrantFiled: January 11, 2008Date of Patent: October 19, 2010Assignee: Cordis CorporationInventors: Laila Al-Marashi, David Grewe, Stephen Griffin, Elaine Lim, David Majercak, Roger Stevens
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Patent number: 7520863Abstract: A bi-directional steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip.Type: GrantFiled: October 23, 2003Date of Patent: April 21, 2009Assignee: Cordis CorporationInventors: David Grewe, David C. Majercak
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Publication number: 20080147001Abstract: A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port.Type: ApplicationFiled: January 11, 2008Publication date: June 19, 2008Inventors: Laila Al-Marashi, David Grewe, Stephen Griffin, Elaine Lim, David Majercak, Roger Stevens
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Publication number: 20070293934Abstract: A system for delivering and deploying an expandable endoluminal prosthesis comprises a delivery catheter and a sheath. The delivery catheter has a proximal end and a distal end and is slidably disposed within a lumen of the sheath. An operating mechanism comprises a contractible air vessel that couples the sheath and the delivery catheter so that contraction of the air vessel causes the sheath to retract proximally over the delivery catheter. Additional aspects of the invention include a method of deploying an expandable endoluminal prosthesis.Type: ApplicationFiled: June 19, 2007Publication date: December 20, 2007Applicant: MED Institute, Inc.Inventor: David Grewe
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Endoluminal medical device for local delivery of cathepsin inhibitors, method of making and treating
Publication number: 20070293937Abstract: An endoluminal medical device comprises a drug release system that releases a cathepsin inhibitor at a predetermined location within a lumen of a patient. The endoluminal devices and methods of treatment of disease can treat illnesses such as aneurysms and aortic dissections.Type: ApplicationFiled: June 1, 2007Publication date: December 20, 2007Inventors: David Biggs, David Grewe, Neal Fearnot, Patrick Ruane, Anthony Ragheb -
Publication number: 20070265699Abstract: The invention relates to a prosthetic valve for regulating flow through a body lumen and delivering a therapeutic agent into said lumen. In one embodiment, the prosthesis includes a frame having an exterior wall, a hollow interior space, a valve member, and at least one aperture through the exterior wall that permits a controlled amount of therapeutic agent loaded into the hollow interior into the surrounding body lumen following implantation. In another embodiment, the prosthesis includes a frame having a groove, a valve member, and therapeutic agent loaded in the groove.Type: ApplicationFiled: April 24, 2007Publication date: November 15, 2007Applicant: MED Institute, Inc.Inventors: David Grewe, James Purdy
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Publication number: 20070255390Abstract: A stent graft introducer actuation assembly (1) having a fixed handle (3) and at least one sliding handle (5, 7), the sliding handle or handles telescoping within the fixed handle, and a winch arrangement (9) to retract the sliding handle into the fixed handle. There may be provided arrangements to give a mechanical advantage to the winch arrangement.Type: ApplicationFiled: April 26, 2007Publication date: November 1, 2007Applicants: William A. Cook Australia Pty. Ltd., MED INSTITUTE, INC.Inventors: Werner Ducke, David Hartley, David Grewe
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Publication number: 20070237973Abstract: This invention is directed to graft materials for implanting, transplanting, replacing, or repairing a part of a patient and to methods of making the graft materials. The present invention is also directed to stent grafts and endoluminal prostheses formed of the graft materials. More specifically, the present invention is a graft material which includes porous polymeric sheet, extracellular matrix material (ECM) disposed on at least a portion of the porous polymeric sheet and at least one polymer layer disposed on at least a portion of the ECM. The ECM may be in a gel form. The polymeric sheet and the polymer layer may be made from foam material and may comprise a polyurethane urea and a surface modifying agent such as siloxane.Type: ApplicationFiled: February 20, 2007Publication date: October 11, 2007Inventors: James Purdy, David Grewe, Kurt Dierking, Lal Ninan, Jichao Sun
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Publication number: 20070219465Abstract: A steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining ribbon which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip. The distal end of the deflection member has “skived,” or tapered, sides to enhance the flexibility of the guidewire.Type: ApplicationFiled: October 31, 2006Publication date: September 20, 2007Inventors: Rudolph Cedro, David Grewe, Hikmat Hojeibane
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Publication number: 20070219464Abstract: A steerable guidewire having a sharpened re-entry tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the re-entry tip.Type: ApplicationFiled: October 31, 2006Publication date: September 20, 2007Inventors: Stephen Davis, David Grewe, Hikmat Hojeibane, Steven Omiecinski
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Publication number: 20070213805Abstract: This invention relates to a medical device and, in particular, to a prosthesis or stent graft assembly for use within the human or animal body and, more particularly, to the fastening of a stent to the graft material of the stent graft assembly or prosthesis.Type: ApplicationFiled: March 5, 2007Publication date: September 13, 2007Applicants: Cook Incorporated, MED Institute, Inc.Inventors: Darin Schaeffer, David Grewe
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Publication number: 20070213689Abstract: A steerable infusion guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil which carry an infusion tube which is attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip of the guidewire.Type: ApplicationFiled: October 31, 2006Publication date: September 13, 2007Inventors: David Grewe, Hikmat Hojeibane
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Publication number: 20070185560Abstract: An expandable stent for medical implantation is described which has a generally cylindrical structure with a central longitudinal axis. At least a portion of the generally cylindrical structure is formed from an arrangement of circumferentially curved structural members. The portion expands from a compressed state to an expanded state by a spiraling motion of each of the structural members about the central longitudinal axis. In the compressed state, each of the structural members may nest within an open region formed by segments composing the structural member, such that the portion of the generally cylindrical structure has no overlapping regions. A ratio of a circumferential length of each structural member to a spacing between adjacent structural members may be in the range of about 1.8 to about 2.3.Type: ApplicationFiled: November 27, 2006Publication date: August 9, 2007Applicant: Cook IncorporatedInventors: Blayne Roeder, Richard Swift, David Grewe
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Publication number: 20070073385Abstract: An intraluminal device is provided with a porous structure. The porous structure may be loaded with a bioactive substance to treat surrounding tissues after the intraluminal device has been implanted. The porous structure may be made by depositing a metal film on a foam structure using chemical vapor deposition. Porous structures may also be made by sintering or applying a ceramic layer to the intraluminal device. An intraluminal device is also provided with a ceramic material applied to generally straight portions of the device structure but not to portions adapted to bend. One advantage is that the ceramic material is less likely to fracture since it is applied to regions that experience less strain.Type: ApplicationFiled: September 18, 2006Publication date: March 29, 2007Applicants: Cook Incorporated, MED Institute, Inc.Inventors: Darin Schaeffer, David Grewe, Patrick Ruane
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Publication number: 20070050010Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: ApplicationFiled: September 1, 2006Publication date: March 1, 2007Applicants: Cook Incorporated, MED Institute, Inc.Inventors: Brian Bates, Anthony Ragheb, Neal Fearnot, William Voorhees, Thomas Kozma, David Grewe, Darin Schaeffer
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Publication number: 20070043423Abstract: Intraluminal devices are provided with an inner cavity. The inner cavity may be loaded with a bioactive substance. Fenestrations extend between an outer surface and the inner cavity. Thus, the bioactive substance may be released from the intraluminal device through the fenestrations.Type: ApplicationFiled: August 10, 2006Publication date: February 22, 2007Applicant: MED Institute Inc.Inventor: David Grewe