Abstract: A composition for reducing copper-induced liver cell death in a subject, such as a human, dog, or cat, is provided. The composition includes L-ergothioneine and chrysophanol in an amount which provides a synergistic effect in the reduction of copper-induced liver cell death. A ratio of the L-ergothioneine to chrysophanol ranges from 1:1 to 1:8. The composition can include the L-ergothioneine in an amount of 100 ?M and the chrysophanol in an amount of 100 ?M, for example. Alternatively, the composition can include the L-ergothioneine in an amount of 12.5 ?M and the chrysophanol in an amount of 100 ?M, for example. The composition can be provided in the form of a liquid, tablet, capsule, soft chew, or another form.

Abstract: The present application relates to compositions comprising avocado/soybean unsaponifiables (“ASU”) and cannabis, and related methods of use. In one embodiment, the cannabis is a cannabis oil extract that is combined with ASU to reduce inflammatory responses and inflammation in humans and animals.

Abstract: A soft chew nutritional supplement for an animal, such as a dog or cat, is provided. The soft chew includes (a) palm oil and/or palm oil constituent, (b) palm kernel oil and/or coconut oil, and (c) at least one other oil. The method of manufacturing the soft chew typically includes partially curing the soft chew at ?79 to 0° C. before packaging the soft chew, and then allowing the soft chew to fully cure while in the packaging at room temperature. To achieve the desired processing and curing of the soft chew, the ratio of the total amount of the components (a) and (b) to the total amount of the (c) other oil ranges from 45:55 to 55:45. In addition, the components (a) and (b) have a Mettler Dropping Point ranging from 36° C. to 40° C. and are present in an amount of 4.5 wt. % to 6.5 wt. %.

Abstract: The present invention provides pants, such as pants that are worn as work uniform pants, which are configured to provide significant improvements in a wearer's comfort, performance, and mobility over a predefined range of motions. Embodiments of the pants comprise one or more stretch panels that are configured to provide for stretching of the pant at an identified micro site in order to provide a wearer with enhanced mobility. Additionally, the manner in which the various portions of the pant are connected together may be adjusted in order to provide a wearer with enhanced mobility.

Abstract: A self-orienting perforating gun includes an outer housing having a throughbore, a charge carrier positioned in the throughbore of the outer housing, a hub secured directly or indirectly to the outer housing, a bearing secured to each carrier end of the charge carrier wherein the bearing overlies the hub to provide a rotatable relationship between the hub and the charge carrier about a rotational axis within the outer housing, and an eccentric weight coupled to the charge carrier applying an off-axis orienting force to the charge carrier for urging the charge carrier to rotate about the rotational axis toward a predefined orientation relative to the direction of gravity.

Abstract: A self-orienting perforating gun includes an outer housing having a throughbore, a charge carrier positioned in the throughbore of the outer housing, a hub secured directly or indirectly to the outer housing, a bearing secured to each carrier end of the charge carrier wherein the bearing overlies the hub to provide a rotatable relationship between the hub and the charge carrier about a rotational axis within the outer housing, and an eccentric weight coupled to the charge carrier applying an off-axis orienting force to the charge carrier for urging the charge carrier to rotate about the rotational axis toward a predefined orientation relative to the direction of gravity.

Abstract: An anxiolytic composition formulated for oral administration to a mammal includes a synergistic combination of L-theanine, at least one of magnolia and an extract of magnolia, and at least one of phellodendron and an extract of phellodendron. The composition may include a combination of an extract of Magnolia officinalis and a extract of Phellodendron amurense. The synergistic combination may provide an anxiolytic change in a release pattern of one or more brain neurotransmitters, such as glutamate and/or ?-aminobutyric acid (GABA).

Abstract: A nutritional supplemental for a human or animal, such as a dog or a cat, which includes a partially hydrophobic coating applied to a tablet, is provided. The tablet includes SAMe (S-Adenosylmethionine) milk thistle, and/or any other hydroscopic raw material. SAMe is typically used as an active ingredient to support the liver of the animal. The coating of the tablet typically includes a polymer or resin, stearic acid as a moisture barrier, and calcium carbonate. The coating may also include a plasticizer and color agent. The polymer or resin is typically hydroxypropyl methyl cellulose, and the plasticizer typically includes triethyl citrate and optionally lecithin.

Abstract: The present invention provides shirts, such as shirts that are worn as work uniform shirts, which are configured to provide significant improvements in a wearer's comfort, performance, and mobility over a predefined range of motions. Embodiments of the shirts comprise one or more stretch panels that are configured to provide for stretching of the shirt at an identified micro site in order to provide a wearer with enhanced mobility. In other embodiments, the manner in which the various portions of the shirt are shaped and connected together, and specifically the connection between the sleeve and the rear panel of the shirt, may be adjusted in order to provide a wearer with enhanced mobility.

Abstract: An anxiolytic composition formulated for oral administration to a mammal includes a synergistic combination of L-theanine, at least one of magnolia and an extract of magnolia, and at least one of phellodendron and an extract of phellodendron. The composition may include a combination of an extract of Magnolia officinalis and a extract of Phellodendron amurense. The synergistic combination may provide an anxiolytic change in a release pattern of one or more brain neurotransmitters, such as glutamate and/or ?-aminobutyric acid (GABA).

Abstract: Compositions are described including a combination of hydroxytyrosol and 3-O-acetyl-11-keto-?-boswellic acid. The hydroxytyrosol may be sourced from an olive extract and the 3-O-acetyl-11-keto-?-boswellic acid may be sourced from a Boswellia serrata extract. The compositions may be formulated for oral administration to a mammalian or an avian subject. Methods for preventing or reducing an inflammatory response in connective tissue are provided, the methods comprising orally administering the compositions to a subject in need thereof.

Abstract: Compositions are described including a synergistic combination of hydroxytyrosol and 3-O-acetyl-11-keto-?-boswellic acid. The hydroxytyrosol may be sourced from an olive extract and the 3-O-acetyl-11-keto-?-boswellic acid may be sourced from a Boswellia serrata extract. The compositions may be formulated for oral administration to a mammalian or an avian subject. Methods for treating, repairing, or reducing damage to connective tissue caused by one or more inflammatory mediators and for reducing levels of one or more inflammatory mediators in connective tissue are provided, the methods comprising orally administering the compositions to a subject in need thereof.

Abstract: A self-orienting perforating gun includes an outer housing having a throughbore, a charge carrier positioned in the throughbore of the outer housing, a hub secured directly or indirectly to the outer housing, a bearing secured to each carrier end of the charge carrier wherein the bearing overlies the hub to provide a rotatable relationship between the hub and the charge carrier about a rotational axis within the outer housing, and an eccentric weight coupled to the charge carrier applying an off-axis orienting force to the charge carrier for urging the charge carrier to rotate about the rotational axis toward a predefined orientation relative to the direction of gravity.

Abstract: An anxiolytic composition includes a synergistic combination of one or more of an L-theanine, an s-adenosylmethionine (SAMe), and optionally an extract of Magnolia, an extract of Phellodendron, and a whey protein.

Abstract: The present invention provides pants, such as pants that are worn as work uniform pants, which are configured to provide significant improvements in a wearer's comfort, performance, and mobility over a predefined range of motions. Embodiments of the pants comprise one or more stretch panels that are configured to provide for stretching of the pant at an identified micro site in order to provide a wearer with enhanced mobility. Additionally, the manner in which the various portions of the pant are connected together may be adjusted in order to provide a wearer with enhanced mobility.

Abstract: An anxiolytic composition formulated for oral administration to a mammal includes a synergistic combination of L-theanine, at least one of magnolia and an extract of magnolia, and at least one of phellodendron and an extract of phellodendron. The composition may include a combination of an extract of Magnolia officinalis and a extract of Phellodendron amurense. The synergistic combination may provide an anxiolytic change in a release pattern of one or more brain neurotransmitters, such as glutamate and/or ?-aminobutyric acid (GABA).

Abstract: A person can use a portable electronic device to electronically purchase or otherwise request a product, service or other deliverable related to audio programming to which the person is listening at the time they initiate the request. The request is fulfilled by a service that analyzes the audio content to identify the deliverable the person desires.

Abstract: The present disclosure application relates to cannabis-containing compositions comprising at least one cannabinoid, provided in a gel formulation. The compositions may include cannabidiol. The source of the cannabidioid may be cannabis, a cannabis extract, or an industrial hemp oil extract. Methods of treating and/or reducing symptoms of an inflammatory response and/or inflammation are described, comprising administering to a subject in need thereof the disclosed compositions.

Abstract: The present invention provides pants, such as pants that are worn as work uniform pants, which are configured to provide significant improvements in a wearer's comfort, performance, and mobility over a predefined range of motions. Embodiments of the pants comprise one or more stretch panels that are configured to provide for stretching of the pant at an identified micro site in order to provide a wearer with enhanced mobility. Additionally, the manner in which the various portions of the pant are connected together may be adjusted in order to provide a wearer with enhanced mobility.

Abstract: The present application relates to compositions comprising avocado/soybean unsaponifiables (“ASU”) and cannabis, and related methods of use. In one embodiment, the cannabis is a cannabis oil extract that is combined with ASU to reduce inflammatory responses and inflammation in humans and animals.