Patents by Inventor David Griffiths

David Griffiths has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210362264
    Abstract: A method of fabricating of an object includes causing a first heat source to heat a feed material to form a melt pool of the feed material on a surface. The method further includes causing a second heat source to heat the melt pool on the surface to regulate grain formation of the feed material in the melt pool as the melt pool cools and solidifies on the surface to form at least a portion of the object. The method also includes causing the first heat source and the second heat source to move relative to the surface as the melt pool is formed and cooled.
    Type: Application
    Filed: May 20, 2020
    Publication date: November 25, 2021
    Inventors: Nathan A. Ashmore, Gary W. Coleman, David Griffiths, Michelangelo Mortello, Robert James Scudamore, Lei Xu
  • Publication number: 20210361253
    Abstract: Described is a method of providing an estimate of radiation dose received by a patient during an imaging scan performed by an imaging system. The method includes receiving patient information about the patient, receiving scan data generated during the imaging scan of the patient by the imaging system, creating a virtual dose model of the patient based upon the patient information and the scan data, receiving a selection of a region of interest of the patient, performing a dose simulation on the virtual dose model of the patient or a portion thereof, and determining, based upon an outcome of the dose simulation, an estimate of the radiation dose received within the region of interest. The imaging scan can be a partial imaging scan of a portion of the patient. Also provided is a system and software for carrying out this method.
    Type: Application
    Filed: April 8, 2019
    Publication date: November 25, 2021
    Inventors: David GRIFFITHS, Arthur UBER, III, Jacob AGRIS, Ting LU, Peter THOMPSON
  • Patent number: 11181521
    Abstract: The present invention relates to a method for capturing a molecular target present in the aqueous phase of a water-in-oil emulsion, said method being based on the use of a binding system comprising (a) a surfactant bearing a functional moiety on its hydrophilic head group and (b) a chemoprobe that acts as a molecular staple between the functionalized surfactant and the molecular target and comprises at least two distinct domains namely (i) at least one capture moiety which is able to specifically bind the molecular target and (ii) at least one binding domain which is able to interact with the functional group of the surfactant through covalent or non-covalent interactions, directly or through a binding intermediary.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 23, 2021
    Assignees: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIÈRES DE LA CHIMIE
    Inventors: Alain Wagner, Sylvain Ursuegui, Michael Ryckelynck, Ketty Pernod, Andrew David Griffiths
  • Patent number: 11174311
    Abstract: It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: November 16, 2021
    Assignees: UCB BIOPHARMA SRL, SANOFI
    Inventors: Alastair David Griffiths Lawson, Daniel John Lightwood, Rebecca Jayne Munro, James Philip O'Connell, John Robert Porter
  • Publication number: 20210332034
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Application
    Filed: June 13, 2019
    Publication date: October 28, 2021
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, Edward L. Conn, John M. Curto, David J. Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Chris Limberakis, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Publication number: 20210323873
    Abstract: Disclosed herein are embodiments of composite hexagonal ferrite materials formed from a combination of Y phase and Z phase hexagonal ferrite materials. Advantageously, embodiments of the material can have a high resonant frequency as well as a high permeability. In some embodiments, the materials can be useful for magnetodielectric antennas.
    Type: Application
    Filed: March 31, 2021
    Publication date: October 21, 2021
    Inventors: Michael David Hill, Srinivas Polisetty, Constance M. Griffith
  • Patent number: 11141535
    Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: October 12, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, Barry Tucker, Ronald Heller, David Griffiths, Matthew Schrauder
  • Publication number: 20210309734
    Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
    Type: Application
    Filed: December 15, 2020
    Publication date: October 7, 2021
    Inventors: Ralph Adams, Terence Seward Baker, Alastair David Griffiths Lawson
  • Patent number: 11117555
    Abstract: A method of producing vehicles comprises: in a vehicle production process, manufacturing vehicle components of different types, and assembling the vehicle components to form vehicles; creating a set of vehicle records, each being a record of one of the vehicles entering active service; performing vehicle repairs on a subset of the vehicles after they have entered active service; creating a respective record of each of the vehicle repairs, each of which comprises or indicates a vehicle age or usage value, and records a vehicle component fault identified in the vehicle repair; receiving at a data processing stage the vehicle records and vehicle repair records, wherein a predictive algorithm executed at the data processing stage processes the received records so as to, for each type of vehicle component: 1) identify a respective set of the vehicle repair records relating to that type of vehicle component, and 2) use the respective set of vehicle repair records to predict a respective number of or resource value
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: September 14, 2021
    Assignee: We Predict Limited
    Inventors: James Gareth Davies, Anthony Peter Griffiths, Christopher Lee Davies, Martyn Neil Jones, Stephen David Norris, Christopher George Reed, Patrick James Tudor, Timothy Peter Davis, David Hong Sau Chung, Michael Paul Nicholas, Kelly Marie Nock, Jonathan Michael Phillips, Ashley Steven Burgess, Nicholas Peter Rees, Steffan Rees
  • Patent number: 11103438
    Abstract: A rinse off hair treatment composition comprising; a. a pressure sensitive adhesive emulsion comprising one or more pressure sensitive polymer, wherein the pressure sensitive polymer is not silicone pressure sensitive polymer, and b. at least one material selected from the group consisting of i) a hair conditioning agent; ii) a hair cleansing agent, and, c. a deposition aid.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: August 31, 2021
    Assignee: Conopeo, Inc.
    Inventors: Christopher David Bentley, Lalitesh Chandra, Llyr Glyndwr Griffiths, Janet Drobits Windisch, Lynsey Joanne Coan
  • Publication number: 20210163455
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, David James Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Yajing Lian, Chris Limberakis, Allyn T. Londregan, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Publication number: 20210166780
    Abstract: The present invention provides a method for generation of multi-domain proteins, more particular antibodies, with an improved native state colloidal stability.
    Type: Application
    Filed: June 5, 2019
    Publication date: June 3, 2021
    Inventors: Ralph ADAMS, James HEADS, Sebastian KELM, Alastair David Griffiths LAWSON
  • Publication number: 20210153513
    Abstract: Food for human consumption is smoked by providing smoke, removing one or more polycyclic aromatic hydrocarbons (PAHs) from the smoke and contacting the food with the treated smoke, or smoking the food and then removing the PAHs from the smoked food. PAH removal is selective, to remove the PAHs that contain 4 or more benzene rings, in particular without significantly changing the volatile profile of the smoked food. A selective filter is provided, as is apparatus comprising a smoke generator, a chamber in which to smoke food, and the selective filter, disposed between the smoke generator and the chamber.
    Type: Application
    Filed: November 30, 2020
    Publication date: May 27, 2021
    Inventors: Huw David Griffiths, David Allan Baines, Jane Ker Parker-Gray
  • Publication number: 20210088424
    Abstract: The present invention generally relates to systems and methods to create stable emulsions with low rates of exchange of molecules between microdroplets.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 25, 2021
    Inventors: Felix Kleinschmidt, Andrew David Griffiths, Francois Caron, Abdeslam El Harrak, Eric Brouzes, Darren R. Link
  • Publication number: 20210073917
    Abstract: Techniques have been developed whereby an actuary-manipulable rating model may be defined and transformed into executable form using automated techniques. By allowing business users to define, review and revise rating models using familiar methodologies and constructs (such as factor tables) and by providing an automated facility for transformation of the rating model into an efficient executable form, systems and techniques in accordance with some embodiments of the present invention facilitate rapid deployment and update of insurance product offerings.
    Type: Application
    Filed: November 9, 2020
    Publication date: March 11, 2021
    Applicant: Versata Development Group, Inc.
    Inventor: David Griffith
  • Patent number: 10934279
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: March 2, 2021
    Assignee: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, David James Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Yajing Lian, Chris Limberakis, Allyn T. Londregan, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Publication number: 20210047298
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 18, 2021
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, Matthew S. Dowling, David Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Gajendra Ingle, Wenhua Jiao, Chris Limberakis, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Patent number: 10898438
    Abstract: A package for delivering a single-dose product includes a softgel capsule which is comprised of at least one gelling agent selected from protein-based gelling agents and polysaccharide-based gelling agents. The capsule shell includes one or more areas of reduced thickness that are preferentially ruptured by exertion of a compressive force on the softgel capsule to create an opening in the capsule shell through which the fill composition can be delivered by spraying or squeezing. A method for manufacturing the softgel capsule having one or more areas of reduced shell thickness is also described.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: January 26, 2021
    Assignee: R.P. Scherer Technologies, LLC
    Inventors: Laura Baruzzi, David Griffith Williams, Sr., Arianna Provenza, Rodrigo Fuscelli Pytel
  • Publication number: 20210015811
    Abstract: Disclosed herein are methods of treating a pulmonary bacterial infection comprising bacteria growing under anaerobic conditions using a fluoroquinolone antibiotic. The fluoroquinolone antibiotic may, for example, be levofloxacin or ofloxacin. Also disclosed are methods of inhibiting bacteria growing under anaerobic conditions by exposing the bacteria to an amount of fluoroquinolone antibiotic effective to inhibit growth of said bacteria.
    Type: Application
    Filed: February 20, 2020
    Publication date: January 21, 2021
    Inventors: Mike DUDLEY, David GRIFFITH, Olga RODNY
  • Patent number: PP33703
    Abstract: A new cultivar of Hydrangea macrophylla plant named ‘Bailmacsix’ that is characterized by its compact plant habit; reaching 40 cm to 92 cm in height and width, its cold hardiness in U.S.D.A. Zone 4, its blooming on both old and new wood, and its inflorescences that are deep pink or deep blue/purple depending on growing conditions.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: November 30, 2021
    Assignee: BAILEY NURSERIES INC.
    Inventors: Michael A. Dirr, Jeff Beasley, Mark Griffith, Rhonda Helvick, Oren McBee, David Jonathan Roberts, Justin Schulze