Patents by Inventor David Guerin

David Guerin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170240567
    Abstract: The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. The present invention provides novel compounds which are inhibitors of JAKs. The invention also provides a method for the treatment and prevention of JAK-mediated diseases and disorders using the novel compounds, as well as pharmaceutical compositions containing the compounds.
    Type: Application
    Filed: October 21, 2015
    Publication date: August 24, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Mark E. Scott, David Guerin, Danielle Molinari, Sam Kattar, Peter Fuller, Christopher Dinsmore, Normon Kong, Yunfeng Bai, Jianmin FU, Yumei Liu, Zhixiang Zheng
  • Patent number: 9725445
    Abstract: Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: August 8, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Matthew Lloyd Childers, Christopher Dinsmore, Peter Fuller, David Guerin, Jason David Katz, Qinglin Pu, Mark E. Scott, Christopher F. Thompson, Hongjun Zhang, Danielle Falcone, Luis Torres, Jason Brubaker, Hongbo Zeng, Jiaqiang Cai, Xiaoxing Du, Chonggang Wang, Yunfeng Bai, Norman Kong, Yumei Liu, Zhixiang Zheng
  • Publication number: 20160280704
    Abstract: Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 29, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Matthew Lloyd Childers, Christopher Dinsmore, Peter Fuller, David Guerin, Jason David Katz, Qinglin Pu, Mark E. Scott, Christopher F. Thompson, Hongjun Zhang, Danielle Falcone, Luis Torres, Jason Brubaker, Hongbo Zeng, Jiaqiang Cai, Xiaoxing Du, Chonggang Wang, Yunfeng Bai, Norman Kong, Yumei Liu, Zhixiang Zheng
  • Publication number: 20160272633
    Abstract: Provided are compounds of Formula I, a JAK inhibitor, and use thereof for the treatment of JAK-mediated diseases by the application.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 22, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Christopher Dinsmore, Peter Fuller, David Guerin, Christopher F. Thompson, Qinglin Pu, Mark E. Scott, Jason David Katz, Ravi Kuruklasuriya, Joshua T. Close, Danielle Falcone, Jason Brubaker, Hongbo Zeng, Yunfeng Bai, Jianmin Fu, Norman Kong, Yumei Liu, Zhixiang Zheng
  • Publication number: 20160272632
    Abstract: The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 22, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Matthew Lloyd Childers, Peter Fuller, David Guerin, Jason David Katz, Qinglin Pu, Mark E. Scott, Christopher F. Thompson, Michelle Martinez, Danielle Falcone, Luis Torres, Yongqi Deng, Ravi Kurukulasuriya, Hongbo Zeng, Yunfeng Bai, Norman Kong, Yumei Liu, Zhixiang Zheng
  • Publication number: 20160272634
    Abstract: The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 22, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Christopher Dinsmore, Peter Fuller, David Guerin, Jason David Katz, Christopher F. Thompson, Danielle Falcone, Wei Deng, Luis Torres, Hongbo Zeng, Yunfeng Bai, Jianmin Fu, Norman Kong, Yumei Liu, Zhixiang Zheng, Mark E. Scott
  • Patent number: 9297115
    Abstract: A process for treating a solid substrate coupled to a polyol, wherein said polyol bears free hydroxyl groups, comprising the grafting of at least one fatty acid having an aliphatic chain comprising at least 12 carbon atoms onto said solid substrate coupled to a polyol by esterification of at least one free hydroxyl group of said polyol.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: March 29, 2016
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), CENTRE TECHNIQUE DU PAPIER
    Inventors: Daniel Samain, Camélia Stinga, David Guerin, Markus Schmid, Klaus Noller
  • Patent number: 9255193
    Abstract: Film having liquid-water, grease, gas and water-vapor barrier properties, comprising a PVA film grafted on the surface with a fatty acid.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: February 9, 2016
    Assignees: CENTRE TECHNIQUE DU PAPIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Nicoleta Camelia Stinga, Daniel Samain, David Guerin
  • Publication number: 20140374044
    Abstract: A process for treating a solid substrate coupled to a polyol, wherein said polyol bears free hydroxyl groups, comprising the grafting of at least one fatty acid having an aliphatic chain comprising at least 12 carbon atoms onto said solid substrate coupled to a polyol by esterification of at least one free hydroxyl group of said polyol.
    Type: Application
    Filed: February 4, 2013
    Publication date: December 25, 2014
    Inventors: Daniel Samain, Camélia Stinga, David Guerin, Markus Schmid, Klaus Noller
  • Publication number: 20140222374
    Abstract: The invention provides a system and method system for measuring agricultural parameters, for example the quantity of an agricultural product such as grass. The system comprising means for triggering a measurement of data and repeating the measurement at a plurality of locations over an area; means for communicating the measurement data to a processing means; and means for calculating the quantity of agricultural product for the area using the processing means. The invention solves a problem of how to effectively and simply measure an agricultural product, such as grass, and provides a benefit by allowing the farmer to quickly and accurately measure their grass in a particular field or area.
    Type: Application
    Filed: September 20, 2012
    Publication date: August 7, 2014
    Inventors: Steven Lock, David Guerin, Jake Byrne, Jerrold C. Manock
  • Publication number: 20140113080
    Abstract: Film having liquid-water, grease, gas and water-vapour barrier properties, comprising a PVA film grafted on the surface with a fatty acid.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), CENTRE TECHNIQUE DU PAPIER
    Inventors: Nicoleta Camelia STINGA, Daniel SAMAIN, David GUERIN
  • Patent number: 8637119
    Abstract: Film having liquid-water, grease, gas and water-vapor barrier properties, comprising a PVA film grafted on the surface with a fatty acid.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: January 28, 2014
    Assignees: Centre Technique du Papier, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Nicoleta Camelia Stinga, Daniel Samain, David Guerin
  • Publication number: 20130236647
    Abstract: The invention relates to a machine for chromatogenous grafting treatment of a scrolling substrate (S) having a hydroxylated face (Fh), comprising: an application device (3) of a grafting reagent on the hydroxylated face (Fh) of the substrate, a heating roller (4) for the development of the grafting reaction on the hydroxylated face (Fh) of the substrate, said roller (4) being provided with a bar-end system (5a, 5b) for applying a face of the substrate (S) against said heating roller (4), an extraction device (6) of the hydrochloric acid produced during the grafting reaction, an application device (7) of an air knife on the treated face of the substrate for eliminating the residual grafting reagent. The invention also relates to a chromatogenous grafting process used in said machine.
    Type: Application
    Filed: November 16, 2011
    Publication date: September 12, 2013
    Applicant: CENTERE TECHNIQUE DU PAPIER
    Inventors: Daniel Samain, David Guerin, André Lemaitre, Laurent Lyannaz, Jean-Luc Guillouty
  • Publication number: 20120264735
    Abstract: The present invention relates to pyridazin-4(1H)-one derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
    Type: Application
    Filed: December 14, 2010
    Publication date: October 18, 2012
    Inventors: Jonathan Young, Barbara Czako, Michael Altman, David Guerin, Michelle Martinez, Alexey Rivkin, Kevin Wilson, Kathryn Lipford, Catherine White, Laura Surdi, Stephanie Chichetti, Matthew H. Daniels, Sean P. Ahearn, Danielle Falcone, Ekundayo Osimboni
  • Publication number: 20110014458
    Abstract: Film having liquid-water, grease, gas and water-vapour barrier properties, comprising a PVA film grafted on the surface with a fatty acid.
    Type: Application
    Filed: December 22, 2008
    Publication date: January 20, 2011
    Applicants: CENTRE TECHNIQUE DU PAPIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS)
    Inventors: Nicoleta Camelia Stinga, Daniel Samain, David Guerin
  • Publication number: 20060293358
    Abstract: The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
    Type: Application
    Filed: June 22, 2006
    Publication date: December 28, 2006
    Inventors: Christopher Dinsmore, Ana Gabarda Ortega, David Guerin, James Jewell, Jason Katz, Jongwon Lim, Michelle Machacek, Ryan Otte, Jonathan Young
  • Publication number: 20060020016
    Abstract: The invention relates to processes and compounds useful for producing modified aspartic acid derivatives, such as aspartic acid aldehyde moieties. Aspartic acid derivatives are useful for preparing caspase inhibitors and/or prodrugs thereof.
    Type: Application
    Filed: March 11, 2005
    Publication date: January 26, 2006
    Inventors: Gerald Tanoury, Minzhang Chen, Andrew Jones, Philip Nyce, Martin Trudeau, David Guerin, John Snoonian