Patents by Inventor DAVID H. ALTREUTER

DAVID H. ALTREUTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OSMOTIC MEDIATED RELEASE SYNTHETIC NANOCARRIERS
    Publication number: 20230139671
    Abstract: This invention relates, at least in part, to osmotic mediated release barrier-free synthetic nanocarriers and methods of production and use.
    Type: Application
    Filed: July 28, 2022
    Publication date: May 4, 2023
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset
  • METHODS FOR PROVIDING POLYMERIC SYNTHETIC NANOCARRIERS FOR GENERATING ANTIGEN-SPECIFIC TOLERANCE IMMUNE RESPONSES
    Publication number: 20220354947
    Abstract: Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments.
    Type: Application
    Filed: December 16, 2021
    Publication date: November 10, 2022
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset, Roberto A. Maldonado
  • Methods for providing polymeric synthetic nanocarriers for generating antigen-specific tolerance immune responses
    Patent number: 11235057
    Abstract: Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: February 1, 2022
    Assignee: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset, Roberto A. Maldonado
  • Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses
    Patent number: 10933129
    Abstract: Disclosed are methods for generating humoral and cytotoxic T lymphocyte (CTL) immune responses in a subject and related compositions.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: March 2, 2021
    Assignee: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Conlin O'Neil, Petr Ilyinskii
  • METHODS FOR PROVIDING POLYMERIC SYNTHETIC NANOCARRIERS FOR GENERATING ANTIGEN-SPECIFIC TOLERANCE IMMUNE RESPONSES
    Publication number: 20190076522
    Abstract: Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments.
    Type: Application
    Filed: August 6, 2018
    Publication date: March 14, 2019
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset, Roberto A. Maldonado
  • Method for providing polymeric synthetic nanocarriers for generating antigen-specific tolerance immune responses
    Patent number: 10039822
    Abstract: Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: August 7, 2018
    Assignee: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset, Roberto A. Maldonado
  • METHODS AND COMPOSITIONS RELATED TO THE USE OF LOW HLB SURFACTANTS IN THE PRODUCTION OF SYNTHETIC NANOCARRIERS COMPRISING A RAPALOG
    Publication number: 20160128986
    Abstract: Disclosed are compositions and methods related to synthetic nanocarriers comprising a hydrophobic carrier material, a rapalog, and a non-ionic surfactant with a hydrophilic-lipophilic balance (HLB) value less than or equal to 10.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Conlin O'Neil, Aaron P. Griset, David H. Altreuter
  • METHODS AND COMPOSITIONS RELATED TO SYNTHETIC NANOCARRIERS WITH RAPAMYCIN IN A STABLE, SUPER-SATURATED STATE
    Publication number: 20160128987
    Abstract: Disclosed are compositions and methods that provide synthetic nanocarriers that comprise hydrophobic polyester carrier material and rapamycin that is in a stable, super-saturated amount. In some embodiments, the synthetic nanocarriers are also initially sterile filterable. In other embodiments, the rapamycin is present in the synthetic nanocarrier compositions in an amount that is less than 50 weight % rapamycin/hydrophobic polyester carrier material in the composition.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Conlin O'Neil, Aaron P. Griset, David H. Altreuter
  • CONTROLLED RELEASE OF IMMUNOSUPPRESSANTS FROM SYNTHETIC NANOCARRIERS
    Publication number: 20150320856
    Abstract: Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments.
    Type: Application
    Filed: July 17, 2015
    Publication date: November 12, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset, Roberto A. Maldonado
  • COMPOSITIONS AND METHODS FOR PRODUCING ANTIGEN-SPECIFIC INDUCED TOLEROGENIC DENDRITIC CELLS WITH SYNTHETIC NANOCARRIERS
    Publication number: 20130059009
    Abstract: Disclosed are antigen-specific induced tolerogenic dendritic cells (itDCs) that are produced from combining itDCs with antigen in particulate form, as well as related compositions and methods.
    Type: Application
    Filed: April 27, 2012
    Publication date: March 7, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Roberto A. Maldonado, Christopher Fraser, David H. Altreuter
  • CONTROL OF ANTIBODY RESPONSES TO SYNTHETIC NANOCARRIERS
    Publication number: 20130039954
    Abstract: Disclosed are synthetic nanocarrier compositions that comprise B cell antigen for desired antibody production and an off-target response attenuating polymeric coating as well as related methods.
    Type: Application
    Filed: July 27, 2012
    Publication date: February 14, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: Lynnelle Ann McNamee Pittet, David H. Altreuter, Yun Gao, Petr Ilyinskii, William Kuhlman
  • SYNTHETIC NANOCARRIERS THAT GENERATE HUMORAL AND CYTOTOXIC T LYMPHOCYTE (CTL) IMMUNE RESPONSES
    Publication number: 20130028941
    Abstract: Disclosed are methods for generating humoral and cytotoxic T lymphocyte (CTL) immune responses in a subject and related compositions.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Conlin O'Neil, Petr Ilyinskii
  • SYNTHETIC NANOCARRIERS COMPRISING POLYMERS COMPRISING MULTIPLE IMMUNOMODULATORY AGENTS
    Publication number: 20130028857
    Abstract: This invention relates to compositions, and related methods, of synthetic nanocarriers that comprise polymers that comprise at least two immunomodulatory agent moieties.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: Yun Gao, David H. Altreuter
  • CONTROLLED RELEASE OF IMMUNOSUPPRESSANTS FROM SYNTHETIC NANOCARRIERS
    Publication number: 20120301498
    Abstract: Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 29, 2012
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset, Roberto A. Maldonado
  • OSMOTIC MEDIATED RELEASE SYNTHETIC NANOCARRIERS
    Publication number: 20120244222
    Abstract: This invention relates, at least in part, to osmotic mediated release barrier-free synthetic nanocarriers and methods of production and use.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 27, 2012
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Aaron P. Griset
  • TARGETED MULTI-EPITOPE DOSAGE FORMS FOR INDUCTION OF AN IMMUNE RESPONSE TO ANTIGENS
    Publication number: 20120070493
    Abstract: Provided herein are compositions and methods related to MHC II binding peptides. In some embodiments, the peptides are obtained or derived from a common source. In other embodiment, the peptides are obtained or derived from an infectious agent to which a subject has been repeatedly exposed.
    Type: Application
    Filed: August 23, 2011
    Publication date: March 22, 2012
    Applicant: Selecta Biosciences, Inc.
    Inventors: CHRISTOPHER FRASER, Grayson B. Lipford, David H. Altreuter
  • COMPOSITIONS THAT INDUCE T CELL HELP
    Publication number: 20110110965
    Abstract: The present invention relates, at least in part, to compositions, and related methods, comprising MHC II binding peptides. In one embodiment, the MHC II binding peptides comprise a peptide having at least 70% identity to a natural HLA-DP binding peptide, HLA-DQ binding peptide, or HLA-DR binding peptide.
    Type: Application
    Filed: August 24, 2010
    Publication date: May 12, 2011
    Applicant: Selecta Biosciences, Inc.
    Inventors: CHRISTOPHER FRASER, GRAYSON B. LIPFORD, ROBERT LAMOTHE, DAVID H. ALTREUTER