Patents by Inventor David H. Burkhardt

David H. Burkhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterologous UTR sequences for enhanced mRNA expression
    Patent number: 11980672
    Abstract: mRNAs containing an exogenous open reading frame (ORF) flanked by a 5? untranslated region (UTR) and a 3? UTR is provided, wherein the 5? and 3? UTRs are derived from a naturally abundant mRNA in a tissue. Also provided are methods for identifying the 5? and 3? UTRs, and methods for making and using the mRNAs.
    Type: Grant
    Filed: June 21, 2022
    Date of Patent: May 14, 2024
    Assignee: ModernaTX, Inc.
    Inventors: David H. Burkhardt, Romesh R. Subramanian, Christian Cobaugh
  • Heterologous UTR Sequences for Enhanced mRNA Expression
    Publication number: 20230050143
    Abstract: mRNAs containing an exogenous open reading frame (ORF) flanked by a 5? untranslated region (UTR) and a 3? UTR is provided, wherein the 5? and 3? UTRs are derived from a naturally abundant mRNA in a tissue. Also provided are methods for identifying the 5? and 3? UTRs, and methods for making and using the mRNAs.
    Type: Application
    Filed: June 21, 2022
    Publication date: February 16, 2023
    Applicant: ModernaTX, Inc.
    Inventors: David H. Burkhardt, Romesh R. Subramanian, Christian Cobaugh
  • Heterologous UTR sequences for enhanced mRNA expression
    Patent number: 11389546
    Abstract: mRNAs containing an exogenous open reading frame (ORF) flanked by a 5? untranslated region (UTR) and a 3? UTR is provided, wherein the 5? and 3? UTRs are derived from a naturally abundant mRNA in a tissue. Also provided are methods for identifying the 5? and 3? UTRs, and methods for making and using the mRNAs.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: July 19, 2022
    Assignee: ModernaTX, Inc.
    Inventors: David H. Burkhardt, Romesh R. Subramanian, Christian Cobaugh
  • Heterologous UTR Sequences for Enhanced mRNA Expression
    Publication number: 20180353618
    Abstract: mRNAs containing an exogenous open reading frame (ORF) flanked by a 5? untranslated region (UTR) and a 3? UTR is provided, wherein the 5? and 3? UTRs are derived from a naturally abundant mRNA in a tissue. Also provided are methods for identifying the 5? and 3? UTRs, and methods for making and using the mRNAs.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 13, 2018
    Applicant: ModernaTX, Inc.
    Inventors: David H. Burkhardt, Romesh R. Subramanian, Christian Cobaugh