Abstract: Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

Abstract: Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

Abstract: Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

Abstract: Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

Abstract: Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

Abstract: Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

Abstract: A carefully controlled amount of hydrogen is diffused into titanium or its alloys at an elevated temperature above the transformation temperature. After the elevated temperature is maintained for an approprate duration of time, eutectoid transformation is performed in an inert atmosphere, again for an appropriate period of time, during which or alternatively after which the hydrogen is removed and the metal cooled to room temperature. A sintered titanium alloy component of the type intended for use as a joint replacement subjected to such a treatment displays a fatigue strength which is noticeably improved over a similar article with an equiaxed or lamellar microstructure.

Abstract: Molten alkaline earth metal halides are used to convert highly stable oxides into the corresponding anhydrous halides. Usually a third reactant, such as silica, is added in order to bind the basic oxide thus formed. The solid oxide compounds (e.g. silicates) which result are wellknown ceramic phases of a high degree of purity.

Abstract: Polymers containing laterally substituted isocyanate groups, prepared from acyl azide monomers and at least one other vinyl monomer, and their preparation are provided. Utilization of the acyl azide monomers avoids the problems in handling and storage of the moisture sensitive and toxic isocyanate monomers.