Abstract: Methods and compositions for treatment of human immunodeficiency virus (HIV) infections have been developed which dampen immune activation with a bias more on the CD4 T cells relative to the CD8 T cell response, inhibit HIV replication, reactivate latent HIV, and inhibit infection of cells by HIV. Pushing latent HIV into active infections with hindrance of cell infection by the reactivated HIV can substantially reduce the number of cells infected with HIV and the viral load of HIV, which is not achieved using just the combination of ART and compounds which activate latent HIV. The methods involve administering to an HIV-infected subject three or more compounds which collectively dampen immune activation with a bias more on the CD4 T cells relative to the CD8 T cell response, inhibit HIV replication, reactivate latent HIV, and inhibiting infection of CD4 T cells by HIV.

Abstract: An on-line server system that selects media information for a user according to the user's preferences. The server system comprises a content subsystem, a profile subsystem, and an administration subsystem. The content subsystem collects, stores, and updates media information. The profile subsystem creates a user profile. The administration subsystem is adapted and constructed to match the user profile with media information from the content subsystem and periodically generate an electronic newsletter.