Patents by Inventor David HALBERT

David HALBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APTAMERS AND USES THEREOF
    Publication number: 20210382059
    Abstract: Methods and compositions are provided for specific aptamers and aptamer pools that bind biomarkers of interest such as microvesicle surface antigens or functional fragments of microvesicle surface antigens. In various embodiments, aptamers of the invention are used in diagnostic, prognostic, or theranostic processes to screen a biological sample for the presence or levels of biomarkers such as microvesicles that are determined to provide a diagnostic, prognostic, or theranostic readout. The diagnosis, prognosis, or theranosis may be related to cancer or other diseases and disorders. The invention also provides methods and composition to facilitate aptamer library screening and aptamer detection methods.
    Type: Application
    Filed: December 21, 2020
    Publication date: December 9, 2021
    Inventors: David Halbert, Valeriy Domenyuk, David Spetzler, Tassilo Hornung, Frank Schäfer, Nianqing Xiao
  • APTAMERS AND USES THEREOF
    Publication number: 20190317099
    Abstract: Methods and compositions are provided for specific aptamers and aptamer pools that bind biomarkers of interest such as microvesicle surface antigens or functional fragments of microvesicle surface antigens. In various embodiments, aptamers of the invention are used in diagnostic, prognostic, or theranostic processes to screen a biological sample for the presence or levels of biomarkers such as microvesicles that are determined to provide a diagnostic, prognostic, or theranostic readout. The diagnosis, prognosis, or theranosis may be related to cancer or other diseases and disorders. The invention also provides methods and composition to facilitate aptamer library screening and aptamer detection methods.
    Type: Application
    Filed: March 6, 2018
    Publication date: October 17, 2019
    Inventors: David Halbert, Valeriy Domenyuk, David Spetzler, Tassilo Hornung, Frank Schafer, Nianqing Xiao
  • Aptamers and uses thereof
    Patent number: 9958448
    Abstract: Methods and compositions are provided for specific aptamers and aptamer pools that bind biomarkers of interest such as microvesicle surface antigens or functional fragments of microvesicle surface antigens. In various embodiments, aptamers of the invention are used in diagnostic, prognostic, or theranostic processes to screen a biological sample for the presence or levels of biomarkers such as microvesicles that are determined to provide a diagnostic, prognostic, or theranostic readout. The diagnosis, prognosis, or theranosis may be related to cancer or other diseases and disorders. The invention also provides methods and composition to facilitate aptamer library screening and aptamer detection methods.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: May 1, 2018
    Assignee: Caris Life Sciences Switzerland Holdings GMBH
    Inventors: David Halbert, Valeriy Domenyuk, David Spetzler, Tassilo Hornung, Frank Schafer, Nianqing Xiao
  • APTAMERS AND USES THEREOF
    Publication number: 20160003835
    Abstract: Methods and compositions are provided for specific aptamers and aptamer pools that bind biomarkers of interest such as microvesicle surface antigens or functional fragments of microvesicle surface antigens. In various embodiments, aptamers of the invention are used in diagnostic, prognostic, or theranostic processes to screen a biological sample for the presence or levels of biomarkers such as microvesicles that are determined to provide a diagnostic, prognostic, or theranostic readout. The diagnosis, prognosis, or theranosis may be related to cancer or other diseases and disorders. The invention also provides methods and composition to facilitate aptamer library screening and aptamer detection methods.
    Type: Application
    Filed: October 23, 2013
    Publication date: January 7, 2016
    Inventors: David HALBERT, Valeriy DOMENYUK, David SPETZLER, Tassilo HORNUNG, Frank SCHAFER, Nianqing XIAO