Patents by Inventor David HANDLEY

David HANDLEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12644880
    Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include the use of an RBC flocculant, for example polyDADMAC, and an approximate blood hematocrit from the type of animal blood being evaluated, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal blood hematocrit, and a calculated RBC packing ratio “?” value for the collection device. A collection device with a BIP is disclosed. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.
    Type: Grant
    Filed: August 29, 2023
    Date of Patent: June 2, 2026
    Assignee: Cypher Medical, LLC
    Inventors: Christopher A. Carew, Jian Ling, David Handley
  • Patent number: 12631618
    Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.
    Type: Grant
    Filed: November 7, 2022
    Date of Patent: May 19, 2026
    Inventors: Christopher A. Carew, Jian Ling, Harold T. Duperier, III, David Handley
  • Publication number: 20250147004
    Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid. A blood indicator panel (BIP) device is provided for rapid blood volume measurement (in mls.) in a fluid (e.g., a collected surgical fluid). An RBC flocculant (e.g., polyDADMAC) may be used to induce more rapid sedimentation of red blood cells from the fluid. A series of markings is provided on one side of the BIP, each marking corresponding to a volume of blood (in milliliters). The markings are calculated by use of a formula: Vb=Vm/(Hct×1.2), wherein Hct is an average blood hematocrit, and 1.2 is an RBC packing ratio value for a conventional 1,200 ml waste collection canister (1.2 alternatively referenced as “?”). The BIP does not employ centrifugation, electronic image transmission or analysis, is temperature independent, and is accurate to about +/?10%.
    Type: Application
    Filed: January 6, 2025
    Publication date: May 8, 2025
    Inventors: Christopher A. CAREW, Jian LING, David HANDLEY
  • Patent number: 12188923
    Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.
    Type: Grant
    Filed: September 1, 2023
    Date of Patent: January 7, 2025
    Assignee: Cypher Medical, LLC
    Inventors: Christopher A. Carew, Jian Ling, David Handley
  • Publication number: 20230408487
    Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include the use of an RBC flocculant, for example polyDADMAC, and an approximate blood hematocrit from the type of animal blood being evaluated, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal blood hematocrit, and a calculated RBC packing ratio “?” value for the collection device. A collection device with a BIP is disclosed. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.
    Type: Application
    Filed: August 29, 2023
    Publication date: December 21, 2023
    Inventors: Christopher A. CAREW, Jian LING, David HANDLEY