Abstract: The invention relates to crystalline forms and processes for preparing a compound of Formula I (I) and pharmaceutically acceptable salts thereof which are useful for the treatment of bacterial infections, particularly mycobacterial infections. The invention also relates to intermediates used in the processes for preparing the compound of Formula I for the treatment of mycobacterial infections such as those caused by Mycobacteria tuberculosis.

Abstract: Methods, computer-readable media, software, and apparatuses are provided to assist a user and vendor in completing an online trusted transaction. Trusted vendor websites are verified and user identities are confirmed through a cyber-security safe logon credentialing system. The vendor can be confident that the user identity has been verified to be who they say they are and the user can be confident that they are using a trusted verified vendor website.

Abstract: A negative pressure amplifier apparatus comprises a first amplifier chamber comprising a first amplifier inlet, a first primary inlet, and a first outlet. The first outlet forms, or is in fluid connection with, an apparatus outlet. The first amplifier chamber is configured to establish, in response to fluid being drawn from the apparatus outlet, a first primary fluid flow from the first primary inlet to the first outlet, and to create a first reduced-pressure zone of fluid at the first amplifier inlet, such that a first fluid flow is drawn through the first amplifier inlet into the first reduced-pressure zone. The first amplifier inlet is positioned downstream of the first primary inlet, such that in use, the first fluid flow is introduced to the first reduced-pressure zone downstream of the first primary inlet. An inhaler apparatus comprising the negative pressure amplification apparatus is also provided.

Abstract: An organizer and hanger having a generally rectangular body with a plurality of protrusions/clips/hooks extending from a front surface for securing or handing objects. The body can also have double sided tape applied to tabs on each opposing end or a hole on one or both of the opposing end tabs for engaging a screw or nail. The protrusions/clips/hooks extend from a front side of the body, where the protrusions/clips/hooks are generally an “s” shape when viewed from the side, where the protrusions/clips/hooks are attached on one end to the body. A small rubber sleeve/pad can be attached to the protrusion/clip/hook portion between the first and second bends along the “s” shape. The rubber sleeve/pad increases the coefficient of friction compared to a metal or plastic without a rubber sleeve/pad. This rubber sleeve/pad is critical to providing a better holding force for some objects and noise reduction.

Abstract: A method of forming a custom air filter is disclosed. In accordance with the method, a first air filter having a first size is provided. A length of support material is also provided and includes a substrate covered with a pressure sensitive adhesive, over which a release layer is disposed. At least a first portion of the first air filter is cut and removed to form a nascent air filter. The length of support material is manipulated to have a channel configuration, and the release layer is removed to expose the pressure sensitive adhesive of the length of support material. The length of support material with the channel configuration is pressed into engagement with the nascent air filter such that the exposed pressure sensitive adhesive bonds to the nascent air filter, thereby forming the custom air filter.

Abstract: A support cushion includes a tub defining a well and a plurality of foam arches positioned in the well. Each foam arch includes an upper curved portion, and each foam arch is positioned in the well such that each upper curved portion is opposite a bottom panel of the tub. A body supporting layer having a first surface and a second surface opposite the first surface is positioned over the well and atop the plurality of flexible foam arches.

Abstract: A method of forming a custom air filter is disclosed. In accordance with the method, a first air filter having a first size is provided. A length of support material is also provided and includes a substrate covered with a pressure sensitive adhesive, over which a release layer is disposed. At least a first portion of the first air filter is cut and removed to form a nascent air filter. The length of support material is manipulated to have a channel configuration, and the release layer is removed to expose the pressure sensitive adhesive of the length of support material. The length of support material with the channel configuration is pressed into engagement with the nascent air filter such that the exposed pressure sensitive adhesive bonds to the nascent air filter, thereby forming the custom air filter.

Abstract: Aspects of the disclosure relate to a system and method for securely authenticating a device via token(s) and/or verification computing device(s). A verification computing device may generate a pseudorandom number or sequence. Based on the pseudorandom number or sequence, the verification computing device may select a first plurality of parameters associated with a user of a device to be authenticated. The verification computing device may transmit, to the device, the pseudorandom number or sequence, and the device may select a second plurality of parameters. The device may generate a token based on the second plurality of parameters. The device may send the token to another device, and the other device may send the token to the verification computing device. The verification computing device may authenticate the device based on the token.

Abstract: A non-transitory computer readable medium stores instructions that, when executed by a processor, cause the processor to utilize artificial intelligence to update a mission for an aircraft flown by a pilot. The instructions include: receiving, from at least one storage device, pre-event preparation information that identifies a mission for the aircraft and includes historical information about the pilot; receiving, from an operator device, event execution information that describes how the aircraft is being flown; comparing the pre-event preparation information to the event execution information and the historical information about the pilot using artificial intelligence to determine a deviation from the mission indicating that the mission will likely not be successful; and updating the mission based on the deviation.

Abstract: Methods, computer-readable media, software, and apparatuses are provided to assist a user and vendor in completing an online trusted transaction. Trusted vendor websites are verified and user identities are confirmed through a cyber-security safe logon credentialing system. The vendor can be confident that the user identity has been verified to be who they say they are and the user can be confident that they are using a trusted verified vendor website.

Abstract: An organizer and hanger having a generally rectangular body with a plurality of protrusions/clips/hooks extending from a front surface for securing or handing objects. The body can also have double sided tape applied to tabs on each opposing end or a hole on one or both of the opposing end tabs for engaging a screw or nail. The protrusions/ clips/hooks extend from a front side of the body, where the protrusions/ clips/hooks are generally an “s” shape when viewed from the side, where the protrusions/clips/hooks are attached on one end to the body. A small rubber sleeve/pad can be attached to the protrusion/clip/hook portion between the first and second bends along the “s” shape. The rubber sleeve/pad increases the coefficient of friction compared to a metal or plastic without a rubber sleeve/pad. This rubber sleeve/pad is critical to providing a better holding force for some objects and noise reduction.

Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.

Abstract: A cyclonic apparatus having an inlet and an outlet comprises a first cyclone chamber having a first cyclone inlet, a first reduced-pressure inlet forming or in fluid connection with the cyclonic-apparatus inlet, and a first outlet forming the cyclonic-apparatus outlet. The first cyclone chamber is operable to establish a cyclonic flow of fluid between the first cyclone inlet and the first outlet in response to fluid being drawn from the first outlet, so as to create a first reduced-pressure zone of fluid at the first reduced-pressure inlet. A drug delivery device in which a source of a medicament is coupled to the cyclonic-apparatus inlet of a cyclonic apparatus.

Abstract: Methods and apparatuses for detecting full waste canister and/or fluid flow path blockage conditions are disclosed. Also disclosed are methods and apparatuses for controlling a pump. In some embodiments, flow of fluid can be restricted in a portion of the fluid flow path. A controller can be configured to compare a difference in pressure values upstream and downstream of a fluid flow restrictor to a pressure difference threshold, and determine based on the comparison whether to activate an alarm indicating the full waste canister condition or the fluid flow path blockage condition. The controller can be additionally or alternatively configured to determine a fluid flow using a flow meter, open a selectable valve in response to a comparison of the fluid flow with a fluid flow threshold, determine fluid flow after opening the valve, and determine based on the fluid flow after opening the valve whether to activate the alarm.

Abstract: Methods, computer-readable media, software, and apparatuses are provided to assist a user and vendor in completing an online trusted transaction. Trusted vendor websites are verified and user identities are confirmed through a cyber-security safe logon credentialing system. The vendor can be confident that the user identity has been verified to be who they say they are and the user can be confident that they are using a trusted verified vendor website.

Abstract: Aspects of the disclosure relate to a system and method for securely authenticating a device via token(s) and/or verification computing device(s). A verification computing device may generate a pseudorandom number or sequence. Based on the pseudorandom number or sequence, the verification computing device may select a first plurality of parameters associated with a user of a device to be authenticated. The verification computing device may transmit, to the device, the pseudorandom number or sequence, and the device may select a second plurality of parameters. The device may generate a token based on the second plurality of parameters. The device may send the token to another device, and the other device may send the token to the verification computing device. The verification computing device may authenticate the device based on the token.

Abstract: Aspects of the disclosure relate to a system and method for securely authenticating a device via token(s) and/or verification computing device(s). A verification computing device may generate a pseudorandom number or sequence. Based on the pseudorandom number or sequence, the verification computing device may select a first plurality of parameters associated with a user of a device to be authenticated. The verification computing device may transmit, to the device, the pseudorandom number or sequence, and the device may select a second plurality of parameters. The device may generate a token based on the second plurality of parameters. The device may send the token to another device, and the other device may send the token to the verification computing device. The verification computing device may authenticate the device based on the token.

Abstract: Disclosed are pharmaceutical compositions comprising tedizolid phosphate, methods of preparing such pharmaceutical compositions, and methods of treating bacterial infections with such pharmaceutical compositions. Specifically, a pharmaceutical composition comprising tedizolid phosphate, an acid; and a suspending agent; and wherein the pH of the composition upon constitution with water is between about pH 2-4.5, is provided, wherein the acid is not citric acid or malic acid.

Abstract: Techniques are described for managing cookies, including separately managing cookie data associated with different browser tabs. Cookie management includes the isolation of whitelisted cookies from server responses into background storage and then back onto server requests, removing those cookies from the response header and thus from the cookie store. This isolation is managed with the concept of tab ownership between parent and child tabs to maintain isolation separately for each owner (e.g., the parent) and its children. Exposure to client pages is handled by placing those cookies into a keyed location in session storage for every tab where that cookie is to be visible. An event is then triggered for that client page to let it know that session storage has been updated.

Abstract: A non-transitory computer readable medium stores instructions that, when executed by a processor, cause the processor to utilize artificial intelligence to update a mission for an aircraft flown by a pilot. The instructions include: receiving, from at least one storage device, pre-event preparation information that identifies a mission for the aircraft and includes historical information about the pilot; receiving, from an operator device, event execution information that describes how the aircraft is being flown; comparing the pre-event preparation information to the event execution information and the historical information about the pilot using artificial intelligence to determine a deviation from the mission indicating that the mission will likely not be successful; and updating the mission based on the deviation.