Abstract: System and method for generating patterns P of aiming and treatment light on target eye tissue (e.g. the retina) of a patient's eye. The system includes light sources for treatment and aiming light, a scanner for generating patterns of spots of the generated light, a controller, and a graphic user interface that allows the user to select one of several possible spot patterns, adjust the spot density and/or spot size, and apply patterns with fixed or varied density. The patterns can be formed of interlaced sub-patterns and/or scanned without adjacent spots being consecutively formed to reduce localized heating. Partially or fully enclosed exclusion zones within the patterns protect sensitive target tissue from exposure to the light.

Abstract: A system and method are provided for fragmenting a crystalline lens, to facilitate its removal from the lens bag during an ophthalmic laser surgery. First, a predetermined pattern is used to make Laser Induced Optical Breakdown (LIOB) cuts that section the lens into asymmetrical, operational segments. At least one operational segment is then selected and softened with a plurality of compact LIOB cuts. Once softened, the selected segment is aspirated. The remaining operational segments are then subsequently removed. During a procedure, an imaging unit can monitor movements of the lens bag to ensure proper placement of the LIOB cuts on the lens.

Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

Abstract: System and method for generating patterns P of aiming and treatment light on target eye tissue (e.g. the retina) of a patient's eye. The system includes light sources for treatment and aiming light, a scanner for generating patterns of spots of the generated light, a controller, and a graphic user interface that allows the user to select one of several possible spot patterns, adjust the spot density and/or spot size, and apply patterns with fixed or varied density. The patterns can be formed of interlaced sub-patterns and/or scanned without adjacent spots being consecutively formed to reduce localized heating. Partially or fully enclosed exclusion zones within the patterns protect sensitive target tissue from exposure to the light.

Abstract: System and method for generating patterns P of aiming and treatment light on target eye tissue (e.g. the retina) of a patient's eye. The system includes light sources for treatment and aiming light, a scanner for generating patterns of spots of the generated light, a controller, and a graphic user interface that allows the user to select one of several possible spot patterns, adjust the spot density and/or spot size, and apply patterns with fixed or varied density. The patterns can be formed of interlaced sub-patterns and/or scanned without adjacent spots being consecutively formed to reduce localized heating. Partially or fully enclosed exclusion zones within the patterns protect sensitive target tissue from exposure to the light.

Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

Abstract: A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area. Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.

Abstract: A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area, Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.

Abstract: In accordance with the present invention, a system and method are provided for removing the corneal epithelium from a patient's eye while monitoring the autofluorescent response that results during laser photoablation of the epithelial tissue. Structurally, the system includes a computer-controlled laser generating unit. Also, connected to the computer are a sensor for receiving the autofluorescent response, and an imaging unit for monitoring changes in the topography during a procedure. By monitoring both the autofluorescent response and changes in epithelial topography, the computer controls the laser unit. When there is no longer an autofluorescent response, the procedure has been completed and the system is shut down.

Abstract: A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area. Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.

Abstract: A system and method for the present invention requires use of a generator, in combination with a radiation unit, to radiate acoustic waveform energy onto a target tissue (i.e. a cellular structure). During radiation of the target tissue in accordance with a predetermined titration-like protocol, the influence of the waveform energy on the cellular structure is periodically monitored. The protocol is stopped when the cellular structure has been transformed or morphed into a desired phenotype.

Abstract: A system and method are provided for treating VitreoRetinal-Interface Syndromes (VRS) by using a femtosecond laser system to relieve vitreoretinal adhesions in an eye. Operationally, fibers in the vitreous body are severed by the laser system to create Posterior Vitreous Detachments (PVD) that relieve the adhesions. In a first embodiment for the present invention, tissue material on selected planes within the vitreous body is photoaltered to sever the fibers. Sequentially, or alternatively, to the first embodiment, in another embodiment, fibers at or near the vitreoretinal interface of the eye are photoaltered for this same purpose.

Abstract: A post-operative procedure is disclosed for inducing a Posterior Vitreous Detachment (PVD) after a VitreoRetinal-Interface Syndrome (VRS) treatment. In the post-op procedure, vitreoretinal interface tissue is imaged to determine the extent of PVD that was established by the VRS treatment and Residual Areas of Adhesion (RAA) are identified on the vitreoretinal interface. Once the RAAs are identified, the next step is to allow gas micro-bubbles on the vitreoretinal interface which were generated during the VRS treatment to move, coalesce, and/or loosen tissue at the vitreoretinal interface, and thereby facilitate completion of a PVD. During the bubble coalescing period, ultrasound energy can be applied to bubble/tissue boundaries to accelerate bubble coalescence and/or increase the rate that RAA tissue is loosened at the vitreoretinal interface. After bubble coalescence, tissue at the RAA can be photoaltered using a focused femtosecond laser beam to induce a suitable PVD.

Abstract: A system and method for creating a line recognition template that replicates an object is provided for use as a control reference during ophthalmic surgery on the object. Creation of the template first requires aligning a plurality of reference points along a central “z” axis, with anatomically measured lengths (?“z”n) between adjacent reference points. Axially-symmetric surfaces can then be traced between selected, adjacent, reference points to create the template. For the present invention, the location of reference points, and the tracing of axially-symmetric surfaces, are based on a cross sectional image of the object for surgery. Preferably, the cross sectional image is obtained using Optical Coherence Tomography (OCT) techniques.

Abstract: In accordance with the present invention, a system and method are provided for using a computer-controlled, laser system to perform a partial vitrectomy of the vitreous humor in an eye. Operationally, an optical channel is first defined through the vitreous humor. Vitreous and suspended deposits (floaters) in the optical channel are then ablated and in some cases removed (e.g. aspirated) from the optical channel. In some instances, a clear liquid can be introduced into the optical channel to replace the ablated matter, and to thereby establish unhindered transparency in the optical channel.

Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

Abstract: System and method for generating patterns P of aiming and treatment light on target eye tissue (e.g. the retina) of a patient's eye. The system includes light sources for treatment and aiming light, a scanner for generating patterns of spots of the generated light, a controller, and a graphic user interface that allows the user to select one of several possible spot patterns, adjust the spot density and/or spot size, and apply patterns with fixed or varied density. The patterns can be formed of interlaced sub-patterns and/or scanned without adjacent spots being consecutively formed to reduce localized heating. Partially or fully enclosed exclusion zones within the patterns protect sensitive target tissue from exposure to the light.