Abstract: A mirror assembly has a pair of telescoping tubular supports extending between a support base and a mirror head to provide adjustment of the mirror head toward and away from the support base. Friction shoes within the tubular supports releasably hold such supports against unintentional telescoping movement. Cooperating stops on the telescoping supports limit outward movement of the mirror head and prevent complete separation of the telescoping supports. The tubular supports are hingedly attached to the support base for rotation about a vertical axis, and cooperating detents and spring elements on the supports and support base releasably hold the supports against rotation.

Abstract: An inertial impact drill for diverse applications in cytology such as in-vitro fertilization, genetic research, pharmaceutical research, cloning, etc., is designed to operate in conjunction with micropipettes, microelectrodes, and micromanipulators. The drill includes two opposing actuators, one version of which is comprised a plurality of individual piezoelectric elements, the other version is comprised of a plurality of electrostrictive elements. The actuators drive a small inertial mass to produce sharp short reciprocal movements of this mass. The movements of the inertial mass result in repetitive impacts that are transferred to the micropipette or a microelectrode, which is mechanically coupled to the body of the inertial impact drill. In addition, the impacts cause mechanical oscillation of the tip of a micropipette or a microelectrode at its resonant frequency that is higher than the repetition rate of the impacts.

Abstract: A primarily electronically set permanent or retrievable downhole tool having a hydraulic contingency arrangement to activate the downhole tool in the conventional way in the event electronic communication fails.

Abstract: A peristaltic driver, also known as an Inchworm.RTM. actuator using stepping, "clamp-extend-clamp", action of a piezoelectric actuator device provides motion in high resolution (steps) of an object, such as a probe of a scanning probe microscope or other optical, electrical and computer elements. The actuator device is an integral body made up of successive pusher and clamping sections. The clamping sections selectively clamp to members which are spaced from each other. An object is moved along a path between the members by being coupled to a pusher section which is disposed in symmetrical relationship with pairs of other pusher sections and pairs of clamping sections. Voltages are applied across the various sections and provide clamping action without transferring net forces in directions along which the object is pushed, thus reducing motion discontinuities each time the clamping sections extend or retract.

Abstract: A process of cyclizing compounds of formula II ##STR1## wherein K, V', R.sup.1 and 1 are as herein defined, is described whereby a compound of formula IVa is produced ##STR2## wherein K, V', R.sup.1, Q, S and 1 are as herein defined. The compounds of formula IVa are useful intermediates in the production of compounds of formula I ##STR3## wherein ring A, B, G, V, Z, R.sup.1 and R.sup.2 are as herein defined.

Abstract: The disclosure relates to cycloalkylene azoles of general Formula I ##STR1## wherein ##STR2## is a carbocyclic or carbopolycyclic group optionally carrying at least on a alkyl substituent,X is a grouping ##STR3## an oxygen or sulfur atom, and Y and Z, independently of each other, are ##STR4## or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are suitable for the preparation of medicinal agents.Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhibiting female fertility.

Abstract: The disclosure relates to cycloalkylene azoles of general Formula I ##STR1## wherein ##STR2## is a carbocyclic or carbopolycyclic group optionally carrying at least one alkyl substituent,is the grouping ##STR3## an oxygen or sulfur atom, and Y and Z, independently of each other, are ##STR4## or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are suitable for the preparation of medicinal agents.Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhbiiting female fertility.

Abstract: Disclosed are novel 14,17.alpha.-etheno- and -ethanoestratrienes according to general Formula I ##STR1## wherein X is a --CH.sub.2 --CH.sub.2 or ##STR2## R.sup.1 is a hydrogen atom, a C.sub.1 - to C.sub.15 -acyl, benzoyl, C.sub.1 - to C.sub.15 -alkyl, C.sub.3 - to C.sub.9 -cycloalkyl or alkylcycloalkyl group, andR.sup.2 is the grouping ##STR3## wherein R.sup.3 and R.sup.4 independently of each other mean a hydrogen atom or a straight-chain or branched, optionally partially or completely fluorinated C.sub.1 -C.sub.8 -alkyl group,a process for their preparation, pharmaceutical preparations containing these compounds, as well as their use for the production of medicinal agents.The novel compounds exhibit strong antiestrogenic efficacy.

Abstract: The disclosure relates to cycloalkylene azoles of general Formula I ##STR1## wherein ##STR2## is a carbocyclic or carbopolycyclic group optionally carrying at least one alkyl substituent,X is the grouping ##STR3## an oxygen or sulfur atom, and Y and Z, independently of each other, are ##STR4## or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are suitable for the preparation of medicinal agents.Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhibiting female fertility.

Abstract: A bearing system comprised of a base made of a magnetic material. The bearing system is also comprised of an element disposed adjacent the base. The element is comprised of a device for creating a separation force and a positive stiffness between the element and the base such that a gap is formed therebetween. The element is also comprised of a device for generating magnetic flux such that a closed magnetic flux circuit is formed through the element, the base and the gap creating a preload force and a negative stiffness between the element and the base. The positive stiffness is greater than a negative stiffness, and the preload force essentially balances the separation force. In a preferred embodiment, the creating device includes a device for flowing fluid through the element such that a fluid pressure is formed between the element and the base, resulting in the presence of the gap and the positive stiffness.

Abstract: New 19,11.beta.-bridged steroids of the general formula I ##STR1## where R.sup.1 stands for a methyl or ethyl radical,R.sup.2 for a hydrogen or chlorine atom or a C.sub.1 -C.sub.4 -alkyl radical,B and G, which are the same or different, respectively for a hydrogen atom, a C.sub.1 -C.sub.4 -alkyl radical or, together, for a second bond between the carbon atoms 6 and 7,B and R.sup.2 together for a methylene or an ethylene group,Z for the radical of a pentagonal or hexagonal ring, which is possibly substituted and possibly unsaturated,V stands for a possibly substituted carbocyclic or heterocyclic aryl radical,the ring A for ##STR2## M and N together meaning a second bond or M a hydrogen atom and N a hydroxy group,X means an oxygen atom, two hydrogen atoms or a hydroxyimino grouping N.about.OH,R.sup.3 and D, which are the same or different, respectively a hydrogen atom, a nitrile radical or a C.sub.1 -C.sub.4 -alkyl radical or, together, a methylene or ethylene group,E a hydrogen atom or a C.sub.1 -C.sub.

Abstract: 13-alkyl-11.beta.-phenyl-gonanes of general formula I ##STR1## wherein A and B together stand for an oxygen atom, a CH.sub.2 group or a second bond between carbon atoms 9 and 10,X is an oxygen atom or the hydroxyimino grouping N.about.OH,R.sub.1 is a straight-chained or branched, saturated or unsaturated alkyl radical with up to 8 carbon atoms, which contains the grouping ##STR2## with X as described above, R.sub.2 is a methyl or ethyl radical in the .alpha. or .beta. position,R.sub.9, R.sub.10, R.sub.11 and R.sub.12 each stand for a hydrogen atom, a hydroxy, alkyl, alkoxy or acyloxy group with 1 to 4 carbon atoms respectively or a halogen atom and R.sub.3 and R.sub.4 have a variety of meanings, have antigestagenic and antiglucocorticoid effects.

Abstract: 11 .beta.-(4-isopropenylphenyl)-estra-4,9-dienes of general Formula I ##STR1## wherein X is an oxygen atom or a hydroxyimino grouping ##STR2## R.sup.1 is a hydrogen atom or a methyl group, R.sup.2 is a hydrogen atom or an acyl residue of 1-10 carbon atoms,R.sup.3 is a hydrogen atom, the cyanomethyl group, --(CH.sub.2).sub.n --, CH.sub.2 Z, --CH.dbd.CH--(CH.sub.2).sub.m Z or --C.dbd.CC--Y wherein n=0 to 5 and m=1 to 4, Z meaning a hydrogen atom or the OR.sup.4 group with R.sup.4 meaning a hydrogen atom, an alkyl or alkanoyl group each of 1-4 carbon atoms, and Y meaning a hydrogen, chlorine, fluorine, iodine or bromine atom, an alkyl, hydroxyalkyl, alkoxyalkyl or acyloxyalkyl group each of 1-4 carbon atoms in the alkyl or acyl residue, possess antiprogestational activity, e.g., for treating hormonal dependent tumors, and also antiglucocorticoidal activity.

Abstract: The invention relates to N-substituted imidazoles, processes for their production as well as their use in pharmaceutical agents. The compounds according to the invention have aromatase-inhibiting properties.

Abstract: The invention relates to N-substituted imidazoles, processes for their production as well as their use in pharmaceutical agents.The compounds according to the invention have aromatase-inhibiting properties.

Abstract: A 3-methylene-4-androsten-17-one of formula I ##STR1## wherein R.sub.a represents a hydrogen atom or a saturated or unsaturated straight-chain or branched-chain, optionally substituted alkyl radical with 1-6 carbon atoms, in which R.sub.a is in the alpha- or beta-position, andR.sub.b represents a hydrogen atom, a hydroxyl or an --S(O).sub.n R.sub.c group, in which R.sub.c is a hydrogen atom or an alkyl or acyl group with 1-4 carbon atoms, n=0, 1 or 2, andX represents CH.sub.2, CHF, CHCl or CHBr, in which if R.sub.a is hydrogen and R.sub.b is hydroxyl or R.sub.a and R.sub.b each are hydrogen, X is not CH.sub.2.The new compounds of formula I are suitable for fertility control and for treatment of diseases which are promoted by estrogens.

Abstract: The invention relates to N-substituted imidazoles of the formula, ##STR1## processes for their production as well as their use in pharmaceutical agents. The compounds according to the invention have aromatase-inhibiting properties and are suitable for therapy of estrogen-caused diseases.

Abstract: A method for the early detection of a pregnancy comprises determination of EPF in the blood or urine or in a biochemical derivative of the blood or urine of pregnant women, by measuring the influence of EPF on the production of electronically excited states or radicals, especially oxygen radicals, or their secondary products, in leukocyte or cell line preparations. The method can also be used to determine gonadal tumors.

Abstract: 1-Methyl-15.alpha.-(1-oxyalkyl)androsta-1,4-diene-3,17-diones of general Formula I ##STR1## wherein R.sup.1 is a hydrogen atom or an acyl group of 1-10 carbon atoms,R.sup.2 is an OR.sup.4, NHR.sup.5 or an S(O).sub.n R.sup.6 group, R.sup.4 being straight- or branched-chain alkyl group of 1-10 carbon atoms, R.sup.5 being an acyl group of 1-10 carbon atoms, R.sup.6 being a straight- or branched-chain alkyl group of 1-10 carbon atoms or an aryl group of 6-10 carbon atoms,R.sup.3 is a hydrogen atom or a straight- or branched-chain alkyl group of 1-8 carbon atoms, and n is 0, 1 or 2,are suitable as inhibitors of estrogen biosynthesis for fertility control and for the treatment of diseases that are evoked by estrogens.

Abstract: 11.beta.-substituted steroids of the formula ##STR1## wherein A and B together represent a second bond between the 6-position and 7-position carbon atoms, or, respectively, are each H;X is O, two H atoms or hydroximino;Z is the residue of a pentagonal or hexagonal ring which is optionally substituted and optionally saturated;R.sup.1 is vinyl, C.sub.3-7 -cyclo-1-alkenyl, phenyl, naphthyl or 5- or 6-membered heterocyclic aromatic having at least one N, O or S atom, each being unsubstituted or substituted by 1-3 halogen atoms, 1-3 C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, C.sub.1-4 -acyl, C.sub.2-10 -alkenyl, C.sub.1-4 -acyloxy, phenyl, nitro, hydroxy, carboxy, cyanide, COOR.sup.4 or amino optionally substituted by 1-2 C.sub.1-4 -alkyl;R.sup.2 is methyl or ethyl,R.sup.3 is H, Cl or methyl; andR.sup.4 is C.sub.1-4 -alkyl optionally substituted by phenyl which itself is optionally substituted by C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, halogen or phenylhave valuable pharmacological properties.