Abstract: Described herein are systems, methods for detecting gaps between lesions formed in tissue during ablation. A system includes a catheter that has proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. A plurality of optical fibers are located within the catheter and are coupled to a computing device. The computing device includes a memory and a processor configured to receive, from the optical fibers, optical measurement data of a portion of tissue during or after an ablation, identify one or more optical properties of the portion of tissue by analyzing the optical measurement data, and detect a presence or an absence of a gap between one or more lesions formed in the portion of tissue based on the one or more optical properties.

Abstract: Disclosed herein are system, method, and computer-readable medium aspects for assessing ablation lesions in realtime. An aspect operates by receiving a first optical measurement data from a first catheter optical port, assigning the first optical measurement data to a first available processing core in a processing unit in order to identify an optical property at a first location of a lesion, and generating a first graphical representation from the optical property at the first location of the lesion. After a predetermined time, the aspect continues to operate by repeating the receiving, assigning, and generating operations for a second optical measurement data using a second available processing core in order to generate a second graphical representation from the optical property at a second location of the lesion. The aspect concludes by displaying the first graphical representation and the second graphical representation on a user interface at a predefined interval.

Abstract: Disclosed herein are system, method, and computer-readable medium aspects for improving the accuracy of an ablation model through synchronization. An aspect operates by activating a catheter energy source, acquiring a catheter energy signal from the catheter energy source, assigning an activation time stamp and deactivation time stamp to the catheter energy signal, and determining a time of ablation based on a time period between the activation time stamp and deactivation time stamp. The aspect continues to operate by acquiring an optical measurement signal from a catheter optical port, assigning an input time stamp and switching time stamp to the optical measurement signal, and processing the optical measurement signal in order to acquire a denaturation result. The aspect concludes by synchronizing the time of ablation and the denaturation result using the time stamps in order to generate a synchronized model and generating an estimated lesion depth from the synchronized model.

Abstract: Described herein are systems and methods for performing optical signal analysis and lesion predictions in ablations. A system includes a catheter coupled to a plurality of optical fibers via a connector that interfaces with a computing device. The computing device includes a memory and a processor configured to receive optical measurement data of a portion of tissue from the catheter. The processor identifies one or more optical properties of the portion of tissue by analyzing the optical measurement data and determines a time of denaturation of the portion of tissue based on the one or more optical properties. A model is created to represent a correlation between lesion depths and ablation times using the time of denaturation, the one or more optical properties, and the predetermined period of time. A predicted lesion depth for a predetermined ablation time is generated using the model.

Abstract: Described herein is a system including a catheter, an optical circuit, a pulsed field ablation energy source, and a processing device. The catheter includes a proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. The optical circuit is configured to transport light at least partially from the proximal section to the distal section and back. The pulsed field ablation energy source is coupled to the catheter and configured to transmit pulsed electrical signals to a tissue sample. The processing device is configured to analyze one or more optical signals received from the optical circuit to determine changes in polarization or phase retardation of light reflected or scattered by the tissue sample, and determine changes in a birefringence of the tissue sample based on the changes in polarization or phase retardation.

Abstract: Described herein are systems and methods for performing optical signal analysis and lesion predictions in ablations. A system includes a catheter coupled to a plurality of optical fibers via a connector that interfaces with a computing device. The computing device includes a memory and a processor configured to receive optical measurement data of a portion of tissue from the catheter. The processor identifies one or more optical properties of the portion of tissue by analyzing the optical measurement data and determines a time of denaturation of the portion of tissue based on the one or more optical properties. A model is created to represent a correlation between lesion depths and ablation times using the time of denaturation, the one or more optical properties, and the predetermined period of time. A predicted lesion depth for a predetermined ablation time is generated using the model.

Abstract: Described herein is a system including a catheter, an optical circuit, a pulsed field ablation energy source, and a processing device. The catheter includes a proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. The optical circuit is configured to transport light at least partially from the proximal section to the distal section and back. The pulsed field ablation energy source is coupled to the catheter and configured to transmit pulsed electrical signals to a tissue sample. The processing device is configured to analyze one or more optical signals received from the optical circuit to determine changes in polarization or phase retardation of light reflected or scattered by the tissue sample, and determine changes in a birefringence of the tissue sample based on the changes in polarization or phase retardation.

Abstract: Described herein is a system including a catheter, an optical circuit, a pulsed field ablation energy source, and a processing device. The catheter includes a proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. The optical circuit is configured to transport light at least partially from the proximal section to the distal section and back. The pulsed field ablation energy source is coupled to the catheter and configured to transmit pulsed electrical signals to a tissue sample. The processing device is configured to analyze one or more optical signals received from the optical circuit to determine changes in polarization or phase retardation of light reflected or scattered by the tissue sample, and determine changes in a birefringence of the tissue sample based on the changes in polarization or phase retardation.

Abstract: An exhaust-gas system for a motor vehicle includes at least one exhaust-gas cleaning system and at least one regeneration device for the exhaust-gas cleaning system, by means of which regeneration device an oxidizable fluid in vapor form can be introduced into the exhaust-gas stream ahead of the exhaust-gas cleaning system. The regeneration device includes a housing with a chamber formed in it as well as a heating element positioned in the chamber, the housing having on its upstream side an inflow opening for exhaust gases and on its downstream side an outlet opening and being arranged in the interior of the exhaust-gas stream.

Abstract: An apparatus comprises an emissions trap and a loading determination device. The emissions trap is configured to trap emissions present in exhaust gas and comprises a first local region and a second local region. The loading determination device is configured to determine emissions loading of the first local region and emissions loading of the second local region. An associated method is disclosed.

Abstract: An apparatus comprises an emissions trap and a transfer function device. The transfer function device is configured to determine a transfer function of the emissions trap wherein the transfer function is representative of loading of the emissions trap. An associated method is disclosed.

Abstract: An apparatus comprises an exhaust system and an injection system. The injection system is configured to vaporize a first liquid portion of an agent into at least one bubble so as to inject a second liquid portion of the agent into the exhaust system by use of the at least one bubble for delivery of the agent to an emission abatement device of the exhaust system. An associated method is disclosed.

Abstract: An apparatus comprises an emissions trap and a transfer function device. The transfer function device is configured to determine a transfer function of the emissions trap wherein the transfer function is representative of loading of the emissions trap. An associated method is disclosed.

Abstract: An apparatus comprises parallel and coaxial first and second exhaust gas passageways, a fuel reformer positioned in the first exhaust gas passageway to generate partial combustion product (e.g., H2 and/or CO), and a component such as an emission abatement device or an internal combustion engine positioned to receive the partial combustion product from the first exhaust gas passageway and exhaust gas from the second exhaust gas passageway. An associated method is disclosed.

Abstract: An apparatus comprises an exhaust system and an injection system. The injection system is configured to vaporize a first liquid portion of an agent into at least one bubble so as to inject a second liquid portion of the agent into the exhaust system by use of the at least one bubble for delivery of the agent to an emission abatement device of the exhaust system. An associated method is disclosed.

Abstract: An apparatus comprises an emissions trap and a loading determination device. The emissions trap is configured to trap emissions present in exhaust gas and comprises a first local region and a second local region. The loading determination device is configured to determine emissions loading of the first local region and emissions loading of the second local region. An associated method is disclosed.

Abstract: An apparatus comprises an emission abatement device and a ratio oscillator. The emission abatement device comprises a NOx trap and a particulate trap. The ratio oscillator is configured to oscillate a ratio of the oxygen content and regenerative agent content of a flow advanced to the emission abatement device so as to alternately partially regenerate the NOx trap and the particulate trap for a plurality of cycles. An associated method is disclosed.