Abstract: The present disclosure provides devices, systems, and methods for capturing and analyzing behavioral and physiological data of subjects for treatment, modification, and manipulation discovery. In some embodiments, a method for classifying a drug is provided. The method includes obtaining observational data concerning an animal subject to which the drug is administered, the observational data acquired using an enclosure for the animal subject, the enclosure instrumented with at least one sensing device. The method also includes extracting features by applying the observational data to a machine-learning feature-extraction component. The method further includes predicting a class label of the drug by applying the features to a machine-learning classifier component, the machine-learning classifier component trained to predict the class label of the drug from, at least in part, the features. The method further includes providing an indication of the class label.

Abstract: A manipulator for supporting heavy as well as lighter test heads in a small footprint includes a body and an interface for supporting a test head from behind. The interface includes a first portion fixedly attached to the body and a second portion fixedly attached to the rear of the test head. The first and second portions of the interface are rotatably coupled together to allow rotation of the test head about its approximate center of mass. Although the weight of the test head is entirely borne from the rear, the test head can still be moved with relatively little applied force, thereby satisfying the requirements for compliant docking.