Patents by Inventor David Hilbert
David Hilbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220290471Abstract: Disclosed are various embodiments providing a device to secure a hinge of a door, such as a hinge of a door on a shipping container. The device includes a body member and a clamp member. The body member is L-shaped and is placed over a the hinge of the door and the clamp member is placed over a door panel and attached to the body member via a bolt inserted through the clamp member to attach to the body member. Access to the bolt is limited by a puck lock attached to the clamp member.Type: ApplicationFiled: March 14, 2022Publication date: September 15, 2022Inventors: Steve J. Castrogiovanni, Matthew David Hilbert
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Patent number: 9187548Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: GrantFiled: January 23, 2012Date of Patent: November 17, 2015Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
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Publication number: 20120213781Abstract: Monovalent and multivalent multispecific complexes including ELP-MRD fusion proteins containing one or more modular recognition domains (MRDs) that bind target antigens are described. The use of these monovalent and multivalent multispecific complexes (e.g., ELP-MRD fusion proteins) in diagnostic, prognostic, and therapeutic applications and methods of making these complexes are also described.Type: ApplicationFiled: February 10, 2012Publication date: August 23, 2012Applicant: Zyngenia, Inc.Inventor: David HILBERT
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Publication number: 20120121606Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: ApplicationFiled: January 23, 2012Publication date: May 17, 2012Applicant: HUMAN GENOME SCIENCES, INC.Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
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Publication number: 20120058119Abstract: The present invention relates to TR21 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human TR21 protein. TR21 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR21 activity.Type: ApplicationFiled: November 14, 2011Publication date: March 8, 2012Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, David Hilbert
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Patent number: 8101181Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: GrantFiled: September 2, 2009Date of Patent: January 24, 2012Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Gil H. Choi, Tristan Vaughan, David Hilbert
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Publication number: 20110293610Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: ApplicationFiled: August 12, 2011Publication date: December 1, 2011Applicant: HUMAN GENOME SCIENCES, INC.Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
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Patent number: 8010527Abstract: Blogs (and other information sources) are recommended to a user based history of user's online activities. The system: (1) processes the user's web history, (2) identifies blog posts (and web pages) that link to pages read by the user, (3) generates multiple relevance scores for each identified post/page, and (4) produces multiple rankings of the corresponding source blogs (and web sites) by aggregating individual relevance scores (or combinations of relevance scores), according to users' preferences. The system allows the discovery of information sources that are likely to be interesting to the user and allows sources lost in the “long tail” to be seamlessly discovered.Type: GrantFiled: June 29, 2007Date of Patent: August 30, 2011Assignee: Fuji Xerox Co., Ltd.Inventors: Laurent Denoue, Daniel Billsus, David Hilbert, John Adcock, Gene Golovchinsky
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Publication number: 20110117093Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: ApplicationFiled: October 28, 2010Publication date: May 19, 2011Applicant: HUMAN GENOME SCIENCES, INC.Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
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Patent number: 7879328Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: GrantFiled: February 10, 2005Date of Patent: February 1, 2011Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Gil H. Choi, Tristan Vaughan, David Hilbert
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Publication number: 20100111953Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: ApplicationFiled: October 23, 2009Publication date: May 6, 2010Applicant: HUMAN GENOME SCIENCES, INC.Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
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Publication number: 20100040624Abstract: The present invention relates to TR21 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human TR21 protein. TR21 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR21 activity.Type: ApplicationFiled: July 20, 2009Publication date: February 18, 2010Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, David Hilbert
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Publication number: 20100003259Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: ApplicationFiled: September 2, 2009Publication date: January 7, 2010Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
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Patent number: 7605236Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: GrantFiled: November 4, 2005Date of Patent: October 20, 2009Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
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Patent number: 7562385Abstract: A physical key is used to propose an association between a guest device and user information and services. Contact-based or contact-less connectors are used to establish the proposed association between the physical key and the guest device. The proposed association then communicated to the dynamic authentication system over a first communication channel. The dynamic authentication system determines a user confirmation over a second communications channel based on a user device and previously determined associations between users, user devices and the physical key. The guest device is then authenticated for access to information and/or services associated with the user. The information retrieved from and/or transmitted to the user's personal information repository is optionally protected using various transformations.Type: GrantFiled: April 20, 2005Date of Patent: July 14, 2009Assignee: Fuji Xerox Co., Ltd.Inventors: Giovanni L Thione, Jonathan Trevor, David Hilbert
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Publication number: 20090006371Abstract: Blogs (and other information sources) are recommended to a user based history of user's online activities. The system: (1) processes the user's web history, (2) identifies blog posts (and web pages) that link to pages read by the user, (3) generates multiple relevance scores for each identified post/page, and (4) produces multiple rankings of the corresponding source blogs (and web sites) by aggregating individual relevance scores (or combinations of relevance scores), according to users' preferences. The system allows the discovery of information sources that are likely to be interesting to the user and allows sources lost in the “long tail” to be seamlessly discovered.Type: ApplicationFiled: June 29, 2007Publication date: January 1, 2009Applicant: FUJI XEROX CO., LTD.Inventors: Laurent Denoue, Daniel Billsus, David Hilbert, John Adcock, Gene Golovchinsky
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Publication number: 20070258981Abstract: The present invention provides chimeric and humanized versions of anti-CD22 mouse monoclonal antibody, HB22.7. The anti-CD22 antibodies of the invention comprise four human or humanized framework regions of the immunoglobulin heavy chain variable region (“VH”) and four human or humanized framework regions of the immunoglobulin light chain variable region (“VK”). The invention further comprises heavy and/or light chain FW regions that contain one or more backmutations in which a human FW residue is exchanged for the corresponding residue present in the parental mouse heavy or light chain. Human or humanized VH framework regions of antibodies of the invention may comprise one or more of the following residues: a valine (V) at position 24 of framework region 1, a glycine (G) at position 49 of framework region 2, and an asparagine (N) at position 73 of framework region 3, numbered according to Kabat.Type: ApplicationFiled: March 6, 2007Publication date: November 8, 2007Inventors: David Hilbert, Tarran Jones, David Williams
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Publication number: 20070153128Abstract: An element, such as a plug on a VGA cable, can communicate with a media storage unit to enable or disable media storage.Type: ApplicationFiled: January 4, 2006Publication date: July 5, 2007Applicant: Fuji Xerox Co., Ltd.Inventors: John Adcock, Laurent Denoue, David Hilbert, Matthew Cooper
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Patent number: 7220840Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.Type: GrantFiled: November 14, 2002Date of Patent: May 22, 2007Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Gil H. Choi, Tristan Vaughan, David Hilbert
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Publication number: 20070077059Abstract: A multi-function device that prints information images onto sheets of photo-addressable media is described. The multi-function device is comprised of an image acquisition component, an image generation component, optional image transformation components and an image projector to illuminate the photo-addressable medium with the optionally transformed information images. The effects of ambient light on the photo-addressable medium are reduced by tuning the response characteristics of the photo-addressable medium to respond to the wavelength of the projected light and/or to interpose band-pass filters that reduce non-projected light incident on the photo-addressable medium. Programmable characteristics of the photo-addressable medium are adjustable to compensate for ambient light. Registration marks on the photo-addressable medium allow the alignment of the projected image with the photo-addressable medium.Type: ApplicationFiled: October 5, 2005Publication date: April 5, 2007Inventors: Laurent Denoue, Jonathan Foote, David Hilbert, Eleanor Rieffel, Lynn Wilcox, Anthony Dunnigan