Patents by Inventor David Hilbert

David Hilbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220290471
    Abstract: Disclosed are various embodiments providing a device to secure a hinge of a door, such as a hinge of a door on a shipping container. The device includes a body member and a clamp member. The body member is L-shaped and is placed over a the hinge of the door and the clamp member is placed over a door panel and attached to the body member via a bolt inserted through the clamp member to attach to the body member. Access to the bolt is limited by a puck lock attached to the clamp member.
    Type: Application
    Filed: March 14, 2022
    Publication date: September 15, 2022
    Inventors: Steve J. Castrogiovanni, Matthew David Hilbert
  • Patent number: 9187548
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: November 17, 2015
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Publication number: 20120213781
    Abstract: Monovalent and multivalent multispecific complexes including ELP-MRD fusion proteins containing one or more modular recognition domains (MRDs) that bind target antigens are described. The use of these monovalent and multivalent multispecific complexes (e.g., ELP-MRD fusion proteins) in diagnostic, prognostic, and therapeutic applications and methods of making these complexes are also described.
    Type: Application
    Filed: February 10, 2012
    Publication date: August 23, 2012
    Applicant: Zyngenia, Inc.
    Inventor: David HILBERT
  • Publication number: 20120121606
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Application
    Filed: January 23, 2012
    Publication date: May 17, 2012
    Applicant: HUMAN GENOME SCIENCES, INC.
    Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Publication number: 20120058119
    Abstract: The present invention relates to TR21 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human TR21 protein. TR21 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR21 activity.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, David Hilbert
  • Patent number: 8101181
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: January 24, 2012
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Publication number: 20110293610
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 1, 2011
    Applicant: HUMAN GENOME SCIENCES, INC.
    Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
  • Patent number: 8010527
    Abstract: Blogs (and other information sources) are recommended to a user based history of user's online activities. The system: (1) processes the user's web history, (2) identifies blog posts (and web pages) that link to pages read by the user, (3) generates multiple relevance scores for each identified post/page, and (4) produces multiple rankings of the corresponding source blogs (and web sites) by aggregating individual relevance scores (or combinations of relevance scores), according to users' preferences. The system allows the discovery of information sources that are likely to be interesting to the user and allows sources lost in the “long tail” to be seamlessly discovered.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: August 30, 2011
    Assignee: Fuji Xerox Co., Ltd.
    Inventors: Laurent Denoue, Daniel Billsus, David Hilbert, John Adcock, Gene Golovchinsky
  • Publication number: 20110117093
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Application
    Filed: October 28, 2010
    Publication date: May 19, 2011
    Applicant: HUMAN GENOME SCIENCES, INC.
    Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
  • Patent number: 7879328
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: February 1, 2011
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Publication number: 20100111953
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Application
    Filed: October 23, 2009
    Publication date: May 6, 2010
    Applicant: HUMAN GENOME SCIENCES, INC.
    Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
  • Publication number: 20100040624
    Abstract: The present invention relates to TR21 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human TR21 protein. TR21 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR21 activity.
    Type: Application
    Filed: July 20, 2009
    Publication date: February 18, 2010
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, David Hilbert
  • Publication number: 20100003259
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Application
    Filed: September 2, 2009
    Publication date: January 7, 2010
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Patent number: 7605236
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: October 20, 2009
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Steven C. Barash, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Patent number: 7562385
    Abstract: A physical key is used to propose an association between a guest device and user information and services. Contact-based or contact-less connectors are used to establish the proposed association between the physical key and the guest device. The proposed association then communicated to the dynamic authentication system over a first communication channel. The dynamic authentication system determines a user confirmation over a second communications channel based on a user device and previously determined associations between users, user devices and the physical key. The guest device is then authenticated for access to information and/or services associated with the user. The information retrieved from and/or transmitted to the user's personal information repository is optionally protected using various transformations.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: July 14, 2009
    Assignee: Fuji Xerox Co., Ltd.
    Inventors: Giovanni L Thione, Jonathan Trevor, David Hilbert
  • Publication number: 20090006371
    Abstract: Blogs (and other information sources) are recommended to a user based history of user's online activities. The system: (1) processes the user's web history, (2) identifies blog posts (and web pages) that link to pages read by the user, (3) generates multiple relevance scores for each identified post/page, and (4) produces multiple rankings of the corresponding source blogs (and web sites) by aggregating individual relevance scores (or combinations of relevance scores), according to users' preferences. The system allows the discovery of information sources that are likely to be interesting to the user and allows sources lost in the “long tail” to be seamlessly discovered.
    Type: Application
    Filed: June 29, 2007
    Publication date: January 1, 2009
    Applicant: FUJI XEROX CO., LTD.
    Inventors: Laurent Denoue, Daniel Billsus, David Hilbert, John Adcock, Gene Golovchinsky
  • Publication number: 20070258981
    Abstract: The present invention provides chimeric and humanized versions of anti-CD22 mouse monoclonal antibody, HB22.7. The anti-CD22 antibodies of the invention comprise four human or humanized framework regions of the immunoglobulin heavy chain variable region (“VH”) and four human or humanized framework regions of the immunoglobulin light chain variable region (“VK”). The invention further comprises heavy and/or light chain FW regions that contain one or more backmutations in which a human FW residue is exchanged for the corresponding residue present in the parental mouse heavy or light chain. Human or humanized VH framework regions of antibodies of the invention may comprise one or more of the following residues: a valine (V) at position 24 of framework region 1, a glycine (G) at position 49 of framework region 2, and an asparagine (N) at position 73 of framework region 3, numbered according to Kabat.
    Type: Application
    Filed: March 6, 2007
    Publication date: November 8, 2007
    Inventors: David Hilbert, Tarran Jones, David Williams
  • Publication number: 20070153128
    Abstract: An element, such as a plug on a VGA cable, can communicate with a media storage unit to enable or disable media storage.
    Type: Application
    Filed: January 4, 2006
    Publication date: July 5, 2007
    Applicant: Fuji Xerox Co., Ltd.
    Inventors: John Adcock, Laurent Denoue, David Hilbert, Matthew Cooper
  • Patent number: 7220840
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: May 22, 2007
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Gil H. Choi, Tristan Vaughan, David Hilbert
  • Publication number: 20070077059
    Abstract: A multi-function device that prints information images onto sheets of photo-addressable media is described. The multi-function device is comprised of an image acquisition component, an image generation component, optional image transformation components and an image projector to illuminate the photo-addressable medium with the optionally transformed information images. The effects of ambient light on the photo-addressable medium are reduced by tuning the response characteristics of the photo-addressable medium to respond to the wavelength of the projected light and/or to interpose band-pass filters that reduce non-projected light incident on the photo-addressable medium. Programmable characteristics of the photo-addressable medium are adjustable to compensate for ambient light. Registration marks on the photo-addressable medium allow the alignment of the projected image with the photo-addressable medium.
    Type: Application
    Filed: October 5, 2005
    Publication date: April 5, 2007
    Inventors: Laurent Denoue, Jonathan Foote, David Hilbert, Eleanor Rieffel, Lynn Wilcox, Anthony Dunnigan