Abstract: The present invention relates to methods and systems for assessing the overall risk of a human female subject for developing a breast cancer phenotype. In particular, the present invention relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.

Abstract: An automated robotic navigational surgical system that will detect dye (which is injected external to this system) that marks the areas of operation. The color and type of dye used will be one that is both distinct and highly reflective. There are four sections to the automated robotic navigational surgical system: Energy Source, Display Unit and Control Arm, Sensor Array, Disposable Tip.

Abstract: The present invention relates to methods and systems for assessing the overall risk of a human female subject for developing a breast cancer phenotype. In particular, the present invention relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: A method for quantitatively assessing a quality of a weld joint includes positioning an electromagnetic radiation source adjacent the weld joint. The electromagnetic radiation source may be aligned to direct a beam of electromagnetic radiation onto the weld joint. A detector for capturing the electromagnetic radiation emitted from the electromagnetic radiation source may be positioned adjacent the weld joint along a side opposite the electromagnetic radiation source, such that the weld joint is positioned between the electromagnetic radiation source and the detector. A radiographic image of the weld joint may be obtained by directing the beam of electromagnetic radiation toward the weld joint and onto the detector. A weld joint quality rating may be determined for the weld joint based at least in part on the radiographic image.

Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.

Abstract: A method for quantitatively assessing a quality of a weld joint includes positioning an electromagnetic radiation source adjacent the weld joint. The electromagnetic radiation source may be aligned to direct a beam of electromagnetic radiation onto the weld joint. A detector for capturing the electromagnetic radiation emitted from the electromagnetic radiation source may be positioned adjacent the weld joint along a side opposite the electromagnetic radiation source, such that the weld joint is positioned between the electromagnetic radiation source and the detector. A radiographic image of the weld joint may be obtained by directing the beam of electromagnetic radiation toward the weld joint and onto the detector. A weld joint quality rating may be determined for the weld joint based at least in part on the radiographic image.

Abstract: The present invention relates to methods and systems for assessing the overall risk of a human female subject for developing a breast cancer phenotype. In particular, the present invention relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.

Abstract: Correlations between polymorphisms and metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided. Methods of diagnosing and treating metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided. Systems and kits for diagnosis and treatment of metabolic syndrome, insulin resistance, obesity, high blood pressure, dyslipidemia, diabetes and/or myocardial infarction are provided.

Abstract: The invention provides a collection of polymorphic sites associated with response to treatment by an SSRI or placebo in depression patients. The polymorphic sites and others in linkage disequilibrium with them are useful in determining whether to treat a patient with an SSRI or include a patient in a clinical trial to test an SSRI.

Abstract: The present invention relates to business methods for discovery of therapeutic and diagnostic products by identifying variations that occur in the human genome, relating these variations to one another, and, ultimately, relating these variations to the genetic bases of phenotype such as disease resistance, disease susceptibility or drug response.

Abstract: Methods, code, and apparatus are used to ensure that groups of experimental subjects selected for inclusion in a study are matched. Individuals are genotyped and the genotype data is used to determine the extent of mismatch between study groups. If groups show evidence of poor matching, then the genotype data is used to better match the study groups.

Abstract: The invention provides nucleic acid segments of the human genome including polymorphic sites, SNP haplotype blocks, SNP haplotype patterns for each block and informative SNPs for each pattern. Allele-specific primers and probes hybridizing to regions flanking these sites are also provided. The nucleic acids, primers and probes are used in applications such as association studies and other genetic analyses.

Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.

Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.

Abstract: A controllable microscopic bubble nucleation in fluid polymer material production method and its apparatus that utilizes a gas pipe disposed in the conveyance screw shaft of a conventional injection or extraction forming mechanism and, furthermore, a microbubble generating component (such as a microscopic perforation vented metal head or a microscopic perforation ceramic head, etc.) installed at the front extremity of the conveyance screw shaft. At the rear extremity of the gas pipe, a pressurization pump or a high pressure gas storage tank is admitted from an air intake opening, enabling the gas to be indirectly heated by an electric heater on the materials pipe. The high temperature gas is thereafter outputted from the microscopic perforations of the microbubble generating component such that high temperature microscopic bubbles are directly admitted into the section of liquid polymer material which is then uniformly amalgamated by the conveyance screw shaft and then deposited into a forming die.

Abstract: A method and system to facilitate the use and application of a sophisticated statistical algorithm to the evaluation and design of case-control genetic association studies. Use of the method and system of the present invention enable the user to relatively easily apply sophisticated statistical analysis to case-control genetic association study design in order to determine whether or not a study will provide a meaningful result before substantial resources are spent.

Abstract: A hamper/sorter (15) for storing and sorting laundry which loads from the front with one or more openings is described. The hamper/sorter (15) is comprised of the main body and two moveable doors, one upper flexible door (5) that slides vertically and a lower rigid door (4) that can be stowed horizontally under the hamper/sorter (15). During operation, the doors adjust the front openings to allow for small or large laundry items to be loaded and unloaded for storing or washing. The upper and lower door edges that meet together are formed at an angle opposite of each other so that the upper door (5) overlaps the lower door (4). A stop plate (14) is installed on the upper door (5) to keep the doors in the normally closed position. This invention is versatile enough to be used as a hamper or sorter in any location that permits its mounting. One or more of these hamper/sorters (15) can also be mounted together in a horizontal row to provide a sorting system.