Patents by Inventor David Holder

David Holder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240260877
    Abstract: A non-invasive method of determining electrical properties within the brain of a human or animal subject is disclosed. Electrodes are disposed across the scalp of the subject, and atomic magnetometer sensors are disposed around the scalp. Then, for each of a plurality of combinations of the electrodes, a probe electrical signal is applied to the electrodes of the combination and magnetic field signals arising from the probe electrical signals are measured at each of a plurality of the atomic magnetometer sensors. The measured magnetic field signals may then be used to determine electrical properties within the brain.
    Type: Application
    Filed: June 8, 2022
    Publication date: August 8, 2024
    Inventors: David Holder, Kirill Aristovich
  • Publication number: 20240225471
    Abstract: An electrode harness for use in carrying out Electrical Impedance Tomography (EIT) on a human or animal subject is disclosed. The electrode harness includes an electrode support a plurality of electrodes on the electrode support for contacting a surface of an external body part of the subject, a plurality of connectors, each connector coupled to a respective electrode of the plurality of electrodes, and a control unit. The control unit includes an interrogator for coupling to the electrodes via the connectors, the interrogator being configured to selectively provide electrical signals to multiple groups of electrodes of the plurality of electrodes and for measuring, in response to the provided electrical signals, electrical response signals at at least some electrodes of the plurality of electrodes, and communication circuitry for transmitting information associated with the electrical response signals to an external computing device. A system and method are also disclosed.
    Type: Application
    Filed: July 9, 2021
    Publication date: July 11, 2024
    Inventor: David Holder
  • Publication number: 20240130629
    Abstract: An electrode harness for use in carrying out Electrical Impedance Tomography (EIT) on a human or animal subject is disclosed. The electrode harness includes an electrode support a plurality of electrodes on the electrode support for contacting a surface of an external body part of the subject, a plurality of connectors, each connector coupled to a respective electrode of the plurality of electrodes, and a control unit. The control unit includes an interrogator for coupling to the electrodes via the connectors, the interrogator being configured to selectively provide electrical signals to multiple groups of electrodes of the plurality of electrodes and for measuring, in response to the provided electrical signals, electrical response signals at at least some electrodes of the plurality of electrodes, and communication circuitry for transmitting information associated with the electrical response signals to an external computing device. A system and method are also disclosed.
    Type: Application
    Filed: July 8, 2021
    Publication date: April 25, 2024
    Inventor: David Holder
  • Patent number: 11745010
    Abstract: A nerve stimulation system including at least one nerve interface device is disclosed. The device includes a cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the cuff portion, each ring of electrodes including a plurality of electrodes, and wherein each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The system includes a stimulation device in communication with the pairs of electrodes to generate different electrical signals for the pairs of electrodes and a control system that causes the different signals to causes different physiological responses.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: September 5, 2023
    Assignees: GALVANI BIOELECTRONICS LIMITED, UCL BUSINESS LTD.
    Inventors: Matteo Donega, Daniel Chew, David Holder, Kirill Aristovich
  • Patent number: 11672972
    Abstract: A nerve interface device including at least one cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the at least one cuff portion, each ring of electrodes including a plurality of electrodes. Each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The plurality of pairs of electrodes includes at least a first pair of electrodes, the first pair of electrodes mounted on the at least one cuff portion. The at least one cuff portion includes an asymmetric configuration about a central axis perpendicular to the longitudinal cuff axis.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: June 13, 2023
    Assignees: Galvani Bioelectronics Limited, UCL Business PLC
    Inventors: Rizwan Bashirullah, Gerald Edwin Hunsberger, Matteo Donega, Daniel Chew, David Holder, Kirill Aristovich
  • Patent number: 11589827
    Abstract: There is provided a nerve activity monitoring method that includes receiving an input signal indicative of activity in a nerve of a subject; receiving physiological data indicative of physiological activity in the subject; establishing a relationship between the physiological data and the input signal; identifying a plurality of periodic portions in the input signal based on the relationship between the physiological data and the input signal; and outputting the periodic portions identified.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 28, 2023
    Assignees: UCL Business PLC, Galvani Bioelectronics Limited
    Inventors: Kirill Aristovich, David Holder, Daniel Chew, Matteo Donega
  • Patent number: 11006881
    Abstract: There is disclosed a method of determining electrical properties in a peripheral nerve of a human or animal subject using a plurality of electrodes spaced around a perimeter of the nerve, by applying a probe electrical signal to each of a plurality of combinations of the electrodes, and using the resulting electrical responses to determine the electrical properties, for example by carrying out an electrical impedance tomography image reconstruction.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: May 18, 2021
    Assignee: UCL Business Ltd
    Inventors: David Holder, Kirill Aristovich
  • Publication number: 20210137463
    Abstract: There is provided a nerve activity monitoring method that includes receiving an input signal indicative of activity in a nerve of a subject; receiving physiological data indicative of physiological activity in the subject; establishing a relationship between the physiological data and the input signal; identifying a plurality of periodic portions in the input signal based on the relationship between the physiological data and the input signal; and outputting the periodic portions identified.
    Type: Application
    Filed: June 22, 2018
    Publication date: May 13, 2021
    Inventors: Kirill ARISTOVICH, David Holder, Daniel CHEW, Matteo DONEGA
  • Publication number: 20210138238
    Abstract: There is provided a nerve interface device including (1, 3) comprising: at least one cuff portion; and a first pair of electrodes mounted on the at least one cuff portion. The cuff portion has an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a cuff axis passing through the passageway. The electrodes of the first pair are spaced apart from one another in the direction of the cuff axis.
    Type: Application
    Filed: June 22, 2018
    Publication date: May 13, 2021
    Inventors: David Holder, Kirill ARISTOVICH, Daniel CHEW, Matteo DONEGA
  • Publication number: 20210093867
    Abstract: A nerve stimulation system is disclosed including a nerve interface device having a cuff that receives a nerve of a user; and first and second rings of electrodes mounted on the cuff, each ring of electrodes including a plurality of electrodes and wherein each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The system includes a stimulation device in communication with the pairs of electrodes to generate different electrical signals for the pairs of electrodes, a signal routing module to store signal routing information necessary to cause a physiological response in a user and to cause the signals to be delivered accordingly, and a configuration module for monitoring and updating the signal routing information based on information detected or received by the nerve stimulation system.
    Type: Application
    Filed: December 11, 2018
    Publication date: April 1, 2021
    Inventors: Matteo DONEGA, Daniel CHEW, David Holder, Kirill ARISTOVICH, Rizwan BASHIRULLAH
  • Publication number: 20200384265
    Abstract: A nerve stimulation system including at least one nerve interface device is disclosed. The device includes a cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the cuff portion, each ring of electrodes including a plurality of electrodes, and wherein each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The system includes a stimulation device in communication with the pairs of electrodes to generate different electrical signals for the pairs of electrodes and a control system that causes the different signals to causes different physiological responses.
    Type: Application
    Filed: December 11, 2018
    Publication date: December 10, 2020
    Inventors: Matteo DONEGA, Daniel CHEW, David Holder, Kirill ARISTOVICH
  • Publication number: 20200316372
    Abstract: A nerve interface device including at least one cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the at least one cuff portion, each ring of electrodes including a plurality of electrodes. Each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The plurality of pairs of electrodes includes at least a first pair of electrodes, the first pair of electrodes mounted on the at least one cuff portion. The at least one cuff portion includes an asymmetric configuration about a central axis perpendicular to the longitudinal cuff axis.
    Type: Application
    Filed: December 11, 2018
    Publication date: October 8, 2020
    Inventors: Rizwan BASHIRULLAH, Gerald Edwin HUNSBERGER, Matteo DONEGA, Daniel CHEW, David Holder, Kirill ARISTOVICH
  • Publication number: 20200113477
    Abstract: There are disclosed methods and apparatus for determining electrical properties in a peripheral nerve of a human or animal subject. A plurality of electrodes are spaced around a perimeter of the peripheral nerve, and a phase separated pair of first and second probe electrical signals are applied simultaneously to a set of respective first and second combinations of electrodes, the phase separated pair of first and second probe electrical signals having different signal phases from each other. One or more combined responses to the phase separated pair are collected at one or more of the plurality of electrodes, and a pair of phase separated electrical responses are collected corresponding to the different signal phases from the one or more combined responses. The pair of phase separated electrical responses are used to determine electrical properties of the peripheral nerve within the perimeter.
    Type: Application
    Filed: June 8, 2018
    Publication date: April 16, 2020
    Inventors: Thomas DOWRICK, Kirill ARISTOVICH, David HOLDER
  • Publication number: 20180092560
    Abstract: There is disclosed a method of determining electrical properties in a peripheral nerve of a human or animal subject using a plurality of electrodes spaced around a perimeter of the nerve, by applying a probe electrical signal to each of a plurality of combinations of the electrodes, and using the resulting electrical responses to determine the electrical properties, for example by carrying out an electrical impedance tomography image reconstruction.
    Type: Application
    Filed: April 20, 2016
    Publication date: April 5, 2018
    Inventors: David Holder, Kirill Aristovich
  • Publication number: 20080247178
    Abstract: A covering for a light source is used to maintain light intensity of the light source when used in a degrading environment, such as one in which dirt, dust, grime, and abrasive particles are abundant and tend to be deposited on the lens or face plate of the light source, such as in an off-road vehicle. The covering includes a substantially transparent protective basal layer with a lower surface having a substantially transparent, removable adhesive coating. The basal layer is arranged and configured for removable adhesive affixation to the aperture surface of the light source. A plurality of substantially transparent protective layers, each having a lower surface, is disposed in sequence one on top of the other and on the basal layer to form a stack. Each of the plurality of layers has a removable adhesive coating disposed on their lower surface for affixation to an adjacent underlying layer.
    Type: Application
    Filed: December 14, 2007
    Publication date: October 9, 2008
    Inventor: David Holder
  • Patent number: 5459470
    Abstract: A system (10) for friend-or-foe identification (IFF) comprises an interrogator unit (18) carried on a first platform (T1) for generating and transmitting a laser beam. A control unit (22) selectively directs the transmitted laser beam toward a second platform (T2). A coding/decoding unit (28) encodes an IFF interrogator message with which a portion of the transmitted laser beam is modulated. A laser reflector (30) carried on the second platform receives the coded laser beam. The reflector is a normally passive reflector which is activated by receipt of the transmitted laser beam. The reflector responds to the IFF message contained in the received laser beam by modulating the unmodulated portion of the transmitted laser beam. This newly modulated portion of the laser beam is reflected back toward the first platform. The coding/encoding unit decodes on the first platform receives and the response, and determines if it corresponds to a predetermined response which identifies the second platform as a "friend".
    Type: Grant
    Filed: June 22, 1993
    Date of Patent: October 17, 1995
    Assignee: Electronics & Space Corp.
    Inventors: John R. Wootton, Gary Waldman, David Holder
  • Patent number: 5434668
    Abstract: A friend-or-foe (IFF) identification system (10) comprises a laser generator (12) for generating and transmitting a laser beam (B). A beam splitter (16) divides the laser beam into two beams. One of the beams (B1) is directed along a reference path (P). This beam is reflected back along the path by a mirror (24) positioned at the end of the path. The other laser beam (B2) is directed at an object (T) to be identified as a friend or foe. This second beam reflects off the object and the return, reflected beam is detected. The reflected beam includes a vibration signature of the object under investigation. The return beam and reference beam are processed together to correct the vibration signature of the object for arty distortions. This allows an accurate target signature to be obtained. Next, the target signature is compared against other signatures. The results of the comparison provide the IFF identification.
    Type: Grant
    Filed: April 1, 1992
    Date of Patent: July 18, 1995
    Assignee: Electronics & Space Corp.
    Inventors: John R. Wootton, Gary Waldman, Gregory L. Hobson, David Holder
  • Patent number: D614682
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: April 27, 2010
    Assignee: Promotion and Display Technology Ltd.
    Inventor: David Holder