Patents by Inventor David Horne
David Horne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20050082259Abstract: A method is described for the surface treatment of metals to improve the strength, flexibility and fatigue life of the metal, which in a preferred embodiment includes the steps of thoroughly cleaning and drying the metal surface, etching the surface of the metal to remove sharp apexes and ends of cracks in the metal surface, water rinsing and drying the metal surface, and coating the surface with a low water miscible, water displacing, low surface tension corrosion preventive compound.Type: ApplicationFiled: March 26, 2004Publication date: April 21, 2005Inventor: David Horne
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Publication number: 20050051646Abstract: The present invention provides a plastic recycling system, including a first granulator for reducing plastic waste to a first particle size. The system also includes a second granulator for reducing plastic waste to a second particle size. A frictional melting stricture is provided which melts the first particles and the second particles via use of a rotating plate.Type: ApplicationFiled: January 30, 2004Publication date: March 10, 2005Applicant: Collex Pty. Ltd.Inventor: David Horne
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Patent number: 6841685Abstract: Methods for making bis-heterocyclic compounds, especially bis-heterocyclic compounds having five and six-membered heterocyclic linkers are described.Type: GrantFiled: June 7, 2001Date of Patent: January 11, 2005Assignee: State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State UniversityInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 6810562Abstract: A spacing member (15) on a hinge arm (1) bears against guide surfaces (22, 231)and locates a hinge pin (16) generally beneath a hinge pin hole in a recess (2) to be mounted on a door to be hingedly mounted on a cabinet which has a frame mounting the hinge arm. Lowering of the recess when so generally located cause a chamfer (161) on the end of the hinge pin (16) to accurately align the hinge pin with the hinge pin hole as the hinge pin (16) enters the hinge pin hole to move the spacing member (15) out of engagement with the guide surfaces (22, 231).Type: GrantFiled: March 25, 2002Date of Patent: November 2, 2004Assignee: APW Electronics Ltd.Inventors: David Horne, John David Schnabel
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Patent number: 6682109Abstract: A door latching mechanism comprises two oppositely-directed, vertically-slideable rods adapted to engage at their outer ends respectively with the top and bottom of a door frame, and a main latch member adapted to engage with a keeper provided on or in the side of the door frame, the latching mechanism comprising a push rod actuating assembly which is connected between the inner ends of the push rods and is engaged by the main latch member, and is so arranged, in use, to urge the push rods in opposite outward directions on latching engagement of the main latch member with the door side frame, the push rod actuating assembly comprising an actuating assembly housing in or on which is mounted first and second gear pinions that are respectively meshed with vertically slideable oppositely-directed push rod bars connected to the respective inner ends of the push rods, the pinions being meshed with respective racks provided on opposite sides of a slider which is slideable substantially horizontally relative to the hType: GrantFiled: July 11, 2001Date of Patent: January 27, 2004Assignee: APW Ltd.Inventors: David Horne, Neil C. Fletcher
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Publication number: 20030232988Abstract: Methods for making bis-heterocyclic compounds, especially bis-heterocyclic compounds having five and six-membered heterocyclic linkers are described. Also described are methods for making an alpha amino ketone synthon that enables facile syntheses of bisindole compounds, including topsentins and dragmacidins.Type: ApplicationFiled: December 5, 2002Publication date: December 18, 2003Inventors: David A. Horne, Kenichi Yakushijin
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Patent number: 6580030Abstract: A panel includes a sheet of metal folded to define an elongate main panel portion (100, 200) along the edges of which are a first longitudinal side flange (101, 201) and a first transverse end flange (103, 203). The first longitudinal side flange is along at least part of its length folded back towards the main panel portion (100, 200) and secured thereto to provide a tubular edge reinforcement of the panel. The first longitudinal side flange (101, 201) has a first longitudinal end which is secured to the first transverse end flange (103, 203). A portion (107) of the first longitudinal side flange (101) generally parallel to the main panel portion (100) has a longitudinal extension (115) which is folded towards the main panel portion (100) and is secured to a portion of the first transverse end flange (103) extending away from the main panel portion (100).Type: GrantFiled: March 22, 2002Date of Patent: June 17, 2003Assignee: APW Electronics LimitedInventor: David Horne
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Patent number: 6528646Abstract: The synthesis of C11N5 marine sponge alkaloids (±)-hymenin (1), stevensine (2), hymenialdisine (3), and debromohymenialdisine (4) is described. These natural products are the primary family members of the sponge metabolites that contain a fused pyrrolo[2,3-c]lazepin-8-one ring system with either a 2-aminoimidazole (AI) or glycocyamidine appendage. The key steps in the synthesis centered around the generation of novel azafulvenium ions and their regioselective heterodimerization with AI in order to create the tricyclic core. A rarely used protodebromination/oxidation strategy was employed to selectively generate the desired a-bromo substitution pattern seen in hymenialdisine (3). In addition, the AI moiety was shown to be a useful precursor to the glycocyamidine unit found in 3 and 4, which suggests that AI derived natural products may be the biogenic forerunners to glycocyamidine metabolites.Type: GrantFiled: December 28, 2000Date of Patent: March 4, 2003Assignee: The Trustees of Columbia University in the City of New YorkInventors: David A. Horne, Kenichi Yakushijin
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Publication number: 20020125600Abstract: The present invention provides a plastic recycling system, including a first granulator for reducing plastic waste to a first particle size. The system also includes a second granulator for reducing plastic waste to a second particle size. A frictional melting structure is provided which melts the first particles and the second particles via use of a rotating plate.Type: ApplicationFiled: October 24, 2001Publication date: September 12, 2002Inventor: David Horne
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Publication number: 20020089184Abstract: DOOR LATCHING MECHANISM A door latching mechanism comprises two oppositely-directed, vertically-slideable rods adapted to engage at their outer ends respectively with the top and bottom of a door frame, and a main latch member adapted to engage with a keeper provided on or in the side of the door frame, the latching mechanism comprising a push rod actuating assembly which is connected between the inner ends of the push rods and is engaged by the main latch member, and is so arranged, in use, to urge the push rods in opposite outward directions on latching engagement of the main latch member with the door side frame, the push rod actuating assembly comprising an actuating assembly housing in or on which is mounted first and second gear pinions that are respectively meshed with vertically slideable oppositely-directed push rod bars connected to the respective inner ends of the push rods, the pinions being meshed with respective racks provided on opposite sides of a slider which is slideable substantially horizoType: ApplicationFiled: July 11, 2001Publication date: July 11, 2002Inventors: David Horne, Neil C. Fletcher
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Patent number: 6399767Abstract: A process for preparing a compound having structure (I) wherein n is an integer from 1-5; each of R1 and R2 independently is optionally substituted C1-C6 alkyl; each of W and X is independently hydrogen or C1-C6 alkyl; Y is O, S or NR3 where R3 is hydrogen, C1-C6 alkyl or a protective group; and Z is a CD ring structure, a steroid structure, or a vitamin D structure, each of which optionally having structure (IV) wherein W, X, Y and Z are defined above, in the presence of a base, with a compound having structure (V) or (v′) wherein n, R1 and R2 are as defined above, and E is an eliminating group.Type: GrantFiled: May 22, 2000Date of Patent: June 4, 2002Assignees: The Trustees of Columbia University in the City of New York, Chugai Seiyaku Kabushiki KaishaInventors: David A. Horne, Noboru Kubodera, Hiroshi Suzuki, Hitoshi Shimizu
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Publication number: 20010012891Abstract: The synthesis of C11N5 marine sponge alkaloids (±)-hymenin (1), stevensine (2), hymenialdisine (3), and debromohymenialdisine (4) is described. These natural products are the primary family members of the sponge metabolites that contain a fused pyrrolo[2,3-c]lazepin-8-one ring system with either a 2-aminoimidazole (AI) or glycocyamidine appendage. The key steps in the synthesis centered around the generation of novel azafulvenium ions and their regioselective heterodimerization with AI in order to create the tricyclic core. A rarely used protodebromination/oxidation strategy was employed to selectively generate the desired a-bromo substitution pattern seen in hymenialdisine (3). In addition, the AI moiety was shown to be a useful precursor to the glycocyamidine unit found in 3 and 4, which suggests that AI derived natural products may be the biogenic forerunners to glycocyamidine metabolites.Type: ApplicationFiled: December 28, 2000Publication date: August 9, 2001Applicant: The Trustees of Columbia University in the City of New YorkInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 6218549Abstract: The subject invention provides a bicyclic aminoimidazole compound, a hydroxyalkyl aminoimidazole compound, a bicyclic pyrrole compound, a hymenin compound, an aldehyde aminoimidazole compound, a ketal aminoimidazole compound, a tricyclic compound, and a tetrahydropurine compound. The subject invention also provides for processes for preparing the compounds.Type: GrantFiled: November 16, 1999Date of Patent: April 17, 2001Assignee: The Trustees of Columbia University in the City of New YorkInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 6211361Abstract: A method for making debromohymenialdisine (DBH) 2 and analogs thereof is described. One embodiment of the present method first comprises forming hymenin 4, and then converting hymenin into DBH 2 as described herein. One such embodiment first comprises providing a compound having Formula 3 where R is independently selected from the group consisting of hydrogen and lower aliphatic, and X is independently selected from the group consisting of hydrogen and halogen. A compound having Formula 3, such as Compound 10 with R and X as hydrogen, is then converted to DBH 2 or an analog thereof. An alternative embodiment of the method comprises forming Compound 30 or Compound 32, which are then directly converted to DBH 2. Alternatively, Compound 30 can be converted to Compound 10, which is then subsequently converted to DBH 2 by reaction with a halogen in the presence of an acid.Type: GrantFiled: July 20, 1999Date of Patent: April 3, 2001Assignee: State of Oregon acting by and through The Oregon State Board of Higher Education on behalf of Oregon, State UniveristyInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 6197954Abstract: The synthesis of C11N5 marine sponge alkaloids (±)-hymenin (1), stevensine (2), hymenialdisine (3), and debromohymenialdisine (4) is described. These natural products are the primary family members of the sponge metabolites that contain a fused pyrrolo[2,3-c]azepin-8-one ring system with either a 2-aminoimidazole (AI) or glycocyamidine appendage. The key steps in the synthesis centered around the generation of novel azafulvenium ions and their regioselective heterodimerization with AI in order to create the tricyclic core. A rarely used protodebromination/oxidation strategy was employed to selectively generate the desired a-bromo substitution pattern seen in hymenialdisine (3). In addition, the AI moiety was shown to be a useful precursor to the glycocyamidine unit found in 3 and 4, which suggests that AI derived natural products may be the biogenic forerunners to glycocyamidine metabolites.Type: GrantFiled: January 30, 1998Date of Patent: March 6, 2001Assignee: The Trustees of Columbia University in the City of New YorkInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 6103899Abstract: The subject invention provides a bicyclic aminoimidazole compound, a hydroxyalkyl aminoimidazole compound, a bicyclic pyrrole compound, a hymenin compound, an aldehyde aminoimidazole compound, a ketal aminoimidazole compound, a tricyclic compound, and a tetrahydropurine compound. The subject invention also provides for processes for preparing the compounds.Type: GrantFiled: November 4, 1998Date of Patent: August 15, 2000Assignee: The Trustees of Columbia University in the City of New YorkInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 5834609Abstract: The subject invention provides a bicyclic aminoimidazole compound, a hydroxyalkyl aminoimidazole compound, a bicyclic pyrrole compound, a hymenin compound, an aldehyde aminoimidazole compound, a ketal aminoimidazole compound, a tricyclic compound, and a tetrahydropurine compound. The subject invention also provides for processes for preparing the compounds. The bicyclic aminoimidazole compounds of the invention have anti-tumor and anti-microbial activity.Type: GrantFiled: October 6, 1995Date of Patent: November 10, 1998Assignee: The Trustees of Columbia University in the City of New YorkInventors: David A. Horne, Kenichi Yakushijin
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Patent number: 5293303Abstract: A circuit board injector/ejector device for use with a circuit board to be accommodated in a rack housed in an enclosure comprises a body adapted to be secured to a front plate secured to the circuit board and a lever pivotally mounted on the body. The device is adapted to assist in providing the force necessary to effect a multiplicity of pin and socket connections at the rear of the circuit board when the circuit board is introduced into a rack and to assist in providing the force necessary to effect disconnection of the multiplicity of pin and socket connections at the rear of the circuit board when the circuit board is withdrawn from the rack.Type: GrantFiled: December 9, 1992Date of Patent: March 8, 1994Assignee: BICC Public Limited CompanyInventors: Neil C. Fletcher, David Horne
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Patent number: 4911231Abstract: A cooling system for use in an enclosure housing heat-emitting electrical and/or electronic apparatus comprises, in combination, a fan unit and, separately formed with respect to the fan unit, a cooling unit 12. The fan unit includes electrically driven fans mounted with their axes vertical and the cooling unit includes open ended tubes arranged side by side with their axes in a horizontal plane and transversely spaced apart to form passages therebetween. One open end of each tube is adjacent the front of the rack and is open to the atmosphere through a grill; the other open end of each tube is spaced inwardly from the rear of the rack and opens into an otherwise fluid-tight compartment in which are housed electrically driven fans and associated deflectors.Type: GrantFiled: October 14, 1988Date of Patent: March 27, 1990Assignee: BICC Public Limited CompanyInventors: David Horne, Clive J. Penfold
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Patent number: D437300Type: GrantFiled: February 3, 2000Date of Patent: February 6, 2001Assignee: APW Electronics LimitedInventor: David Horne