Abstract: Software systems and methods convert algorithms and software codes into time affecting linear pathways (TALPs) via decomposition and convert paired Input/Output (I/O) datasets into TALPs via Value Complexity polynomials. Generated TALPs can be enhanced through merging with other TALPs. TALPs can be grouped by matching the outputs of the TALP-associated prediction polynomials with some set of given criteria into families and cross-families that are useful in a new type of software optimization that allows for output values of grouped TALPs to be modeled, pooled, discretized and optimized to enhance goals or meet user goals.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for detecting a continued conversation are disclosed. In one aspect, a method includes the actions of receiving first audio data of a first utterance. The actions further include obtaining a first transcription of the first utterance. The actions further include receiving second audio data of a second utterance. The actions further include obtaining a second transcription of the second utterance. The actions further include determining whether the second utterance includes a query directed to a query processing system based on analysis of the second transcription and the first transcription or a response to the first query. The actions further include configuring the data routing component to provide the second transcription of the second utterance to the query processing system as a second query or bypass routing the second transcription.

Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder that includes multiple receptacle wells. Each well can receive a receptacle and has a through-hole extending from an inner surface of the well to an outer surface of the holder. The apparatus includes multiple optical fibers, and each optical fiber has a first end in optical communication with an associated well and a second end in optical communication with an excitation signal source and/or an emission signal detector. The first end of each optical fiber is moveable with respect to the through-hole. A cover is movable between an open position and a closed position relative to the receptacle holder, and the first end of each optical fiber moves with respect to the through-hole of the associated well as the cover moves to the open or closed position or when the cover moves into or out of contact with any receptacles within the wells.

Abstract: Software systems and methods convert algorithms and software codes into time affecting linear pathways (TALPs) via decomposition and convert paired Input/Output (I/O) datasets into TALPs via Value Complexity polynomials. Generated TALPs can be enhanced through merging with other TALPs. TALPs can be grouped by matching the outputs of the TALP-associated prediction polynomials with some set of given criteria into families and cross-families that are useful in a new type of software optimization that allows for output values of grouped TALPs to be modeled, pooled, discretized and optimized to enhance goals or meet user goals.

Abstract: Software systems and methods convert algorithms and software codes into time affecting linear pathways (TALPs) via decomposition and convert paired Input/Output (I/O) datasets into TALPs via Value Complexity polynomials. Generated TALPs can be enhanced through merging with other TALPs. TALPs can be grouped by matching the outputs of the TALP-associated prediction polynomials with some set of given criteria into families and cross-families that are useful in a new type of software optimization that allows for output values of grouped TALPs to be modeled, pooled, discretized and optimized to enhance goals or meet user goals.

Abstract: A method includes receiving a spoken utterance that includes a plurality of words, and generating, using a neural network-based utterance classifier comprising a stack of multiple Long-Short Term Memory (LSTM) layers, a respective textual representation for each word of the of the plurality of words of the spoken utterance. The neural network-based utterance classifier trained on negative training examples of spoken utterances not directed toward an automated assistant server. The method further including determining, using the respective textual representation generated for each word of the plurality of words of the spoken utterance, that the spoken utterance is one of directed toward the automated assistant server or not directed toward the automated assistant server, and when the spoken utterance is directed toward the automated assistant server, generating instructions that cause the automated assistant server to generate a response to the spoken utterance.

Abstract: Multiple receptacles containing a reaction mixture are transported to corresponding receptacle wells of a thermally-conductive receptacle holder in thermal communication with a support that is in thermal communication with a heat sink. The heat sink is pre-heated to a temperature above ambient temperature, and the temperature of the receptacle holder is cycled. Optical communication is established between each of the receptacle wells and an excitation signal source and an emission signal detector during cycling, and whether an emission signal is emitted from any of the receptacles is determined as an indication of the presence of a target nucleic acid.

Abstract: The present disclosure provides formulations of an HGF/SF mimetic, terevalefim, as well as methods of preparing and using the formulations. The present disclosure also provides methods of synthesizing terevalefim.

Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with front and back surfaces. The front surface includes a row of receptacle wells, and an outer surface of each well has a frustoconical shape, an inner surface of each well receives a receptacle, and each well has a through-hole extending between the inner and outer surfaces thereof. One or more thermal elements in contact with the back surface of the holder alter a temperature(s) of the holder. The apparatus includes multiple optical fibers, and each optical fiber provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A first end of each optical fiber is disposed outside, within, or extends through the through-hole of a corresponding well, and a second end of each optical fiber is in optical communication with the excitation signal source and/or the emission signal detector.

Abstract: Methods and systems for existing software applications to automatically take advantage of multicore computer systems outside of the conventional simultaneous processing of multiple applications and without performance problems from cache misses and mismatched task processing times are presented. Unlike other multicore optimization techniques, the present invention uses techniques that are applied to design graphs and work for scaled and standard speedup-based parallel processing. The methods and systems optimize software designs that are attached to code for maximum performance on multicore computer hardware by analyzing and modifying loop structures to produce a general parallel solution, not just simple loop unrolling.

Abstract: A system and method of generating a wellbore layout are disclosed herein. A computing system receives, from a client device, one or more parameters associated with a target location for the target wellbore layout. The computing system receives, from the client device, one or more constraints for the target wellbore layout. The computing system generates a plurality target wellbore layout based on the parameters and constraints in accordance with a plurality of configurations as defined by one or more genetic algorithms. The computing system evaluates each target wellbore layout to generate an overall fitness score. The computing system selects a target wellbore layout with the highest scoring score of each generated overall fitness score, repeating the process until an optimal wellbore layout is selected.

Abstract: A firearm suppressor including a body, the body defining a housing and a core, the core including a baffle system; the housing, core and baffle system monolithic in configuration,

Abstract: Processing within a computing environment is facilitated by generating a hybrid security certificate using multiple cryptosystems. The generating includes obtaining data for inclusion in the hybrid security certificate, and generating a first digital signature associated with a first cryptosystem to cover the data, and a second digital signature associated with a second cryptosystem to cover the data. The generating further includes providing the hybrid security certificate, where the hybrid security certificate includes the data, the first digital signature associated with the first cryptosystem, and the second digital signature associated with the second cryptosystem, and where the first digital signature has no dependency on a key of the second cryptosystem or the second digital signature, and the second digital signature has no dependency on a key of the first cryptosystem or the first digital signature.

Abstract: Methods and systems for automatic innovation determination and use are provided such that objective levels of innovation, efficiency, and complexity can be determined for a software system during the software design and construction process, allowing developers and management to understand and predict not only the contributions of individuals, or teams, but also the worth of those contributions. Further, metrics can be used to determine if two or more implementations of some product actually represent the same or closely linked solutions.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for detecting a continued conversation are disclosed. In one aspect, a method includes the actions of receiving first audio data of a first utterance. The actions further include obtaining a first transcription of the first utterance. The actions further include receiving second audio data of a second utterance. The actions further include obtaining a second transcription of the second utterance. The actions further include determining whether the second utterance includes a query directed to a query processing system based on analysis of the second transcription and the first transcription or a response to the first query. The actions further include configuring the data routing component to provide the second transcription of the second utterance to the query processing system as a second query or bypass routing the second transcription.

Abstract: An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with multiple receptacle wells. Each well has a through-hole extending from an inner surface of the well to an outer surface of the holder. A cover is rotatable between an open position and a closed position relative to the holder and is configured to exert a force onto any receptacles in the wells when the cover is in the closed position. The apparatus includes multiple optical fibers, and each of the optical fibers provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A thermal element is positioned between a thermally-conductive support and the receptacle holder.

Abstract: A software enhancement and management system (E&M System) can include two ways to decompose existing software such that new functionality can be added: functional decomposition and time-affecting linear pathway (TALP) decomposition. Functional decomposition captures the inputs and outputs of the existing software's functions and attaches the new algorithmic constructs presented as other functions that receive the outputs of the existing software's functions. TALP decomposition allows for the generation of time-prediction polynomials that approximate time-complexity functions, speedup, and automatic dynamic loop-unrolling-based parallelization for each TALP.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for detecting a continued conversation are disclosed. In one aspect, a method includes the actions of receiving first audio data of a first utterance. The actions further include obtaining a first transcription of the first utterance. The actions further include receiving second audio data of a second utterance. The actions further include obtaining a second transcription of the second utterance. The actions further include determining whether the second utterance includes a query directed to a query processing system based on analysis of the second transcription and the first transcription or a response to the first query. The actions further include configuring the data routing component to provide the second transcription of the second utterance to the query processing system as a second query or bypass routing the second transcription.

Abstract: Software systems and methods convert algorithms and software codes into time affecting linear pathways (TALPs) via decomposition and convert paired Input/Output (l/O) datasets into TALPs via Value Complexity polynomials. Generated TALPs can be enhanced through merging with other TALPs. TALPs can be grouped by matching the outputs of the TALP-associated prediction polynomials with some set of given criteria into families and cross-families that are useful in a new type of software optimization that allows for output values of grouped TALPs to be modeled, pooled, discretized and optimized to enhance goals or meet user goals.

Abstract: A lensmeter system may include a mobile device having a camera. The camera may capture a first image of a pattern through a lens that is separate from the camera, while the lens is in contact with a pattern. The mobile device may determine the size of the lens based on the first image and known features of the pattern. The camera may capture a second image of the pattern, while the lens is at an intermediate location between the camera and the pattern. The second image may be transformed to an ideal coordinate system, and processed determine a distortion of the pattern attributable to the lens. The mobile device may measure characteristics of the lens based on the distortion. Characteristics of the lens may include a spherical power, a cylinder power, and/or an astigmatism angle.