Abstract: A metered-dose inhaler includes at least one vessel and an actuator for receiving the at least one vessel. The at least one vessel includes a first reservoir containing a first formulation and a second reservoir containing a second formulation. The metered-dose inhaler is actuable when the at least one vessel is received by the actuator. The metered-dose inhaler is configured to simultaneously deliver a first metered dose of the first formulation and a second metered dose of the second formulation upon actuation.

Abstract: A valve for use with a pressurized dispensing container containing a liquid, the valve including a slidable valve stem, the valve stem including an inlet port for conveyance, in use, of liquid from the pressurized dispensing container into the valve stem, and a flange against which biases the valve stem into a non-dispensing position, wherein an external opening of the inlet port is located within the flange.

Abstract: Systems and methods for analysis and generating reports presenting analysis involving capturing unstructured data from online information services. Speaker attributes and semantic attributes associated with items of the captured data are determined. The captured data, speaker attributes, and semantic attributes are analyzed to generate processed information based on the captured data. A report is generated to present the processed information.

Abstract: An apparatus comprises a variable acoustic source and a microphone, both acoustically coupled to a volume having a fluid region and an air region. The apparatus also can include a processor to determine a volume of the air region based on signals received from the microphone and the variable acoustic source. A fluid valve is coupled to the processor, and is configured to allow an amount of fluid to exit the fluid region associated with the volume of the air region. An atomizer, coupled to the fluid region, is configured to aerosolize at least a portion of the fluid.

Abstract: A valve for use with a pressurised dispensing container (30) containing a liquid (31), the valve comprising a slidable valve stem (11), the valve stem comprising an inlet port (24) for conveyance, in use, of liquid from the pressurised dispensing container into the valve stem, and a flange (26) against which acts a biasing means (25) which biases the valve stem into a non-dispensing position, wherein an external opening of the inlet port is located within the flange.

Abstract: The present invention relates to an inhalation apparatus for dispensing substances for inhalation and, in particular, but not exclusively, for dispensing medicinal products in aerosol form from a pressurised dispensing container. An inhalation apparatus (1) is provided for dispensing a product comprising housing (20) adapted to receive a pressurised dispensing container (10) and a mouthpiece (22). The apparatus also comprises a duct for conveying, in use, product from the container to the mouthpiece, a sliding seal member (44, 45) movable under action of triggering means (60) between a first position in which the duct is closed and a second position in which the duct is open, wherein a spring means (50) is provided to bias the sliding seal member towards the second position.

Abstract: The present invention relates to an inhalation apparatus for dispensing substances for inhalation and, in particular, but not exclusively for dispensing medicinal products. An inhalation apparatus is provided having a housing defining a socket for receiving a pressurized dispensing container, an actuator for receiving a valve stem of the pressurized dispensing container and a cylindrical chamber having an inlet located at a periphery of the chamber and an outlet at or near a center of the chamber.

Abstract: This invention relates to an inhalation apparatus for dispensing substances for inhalation and, in particular, but not exclusively, for dispensing medicinal products in aerosol form from a pressurized dispensing container. The inhalation apparatus comprises an inhaler apparatus for dispensing a product comprising a housing having a portion adapted to receive a pressurized dispensing container of a product and a mouthpiece. The apparatus further comprises duct means communicating with the container, said duct means having an outlet defining the direction of flow of the product towards the mouthpiece section. Air inlet valve means are provided comprising at least one air inlet for allowing air into the housing and an airflow controller is biased to seal said air inlet. The airflow controller is manually movable to unseal the air inlet to allow air to flow into the housing when a user applies suction to the mouthpiece.

Abstract: The invention relates to inhaler products, such as medicaments, and particularly to an inhaler for transferring to a patient a metered dose of medicament contained in a pressurized dispensing container. The inhaler includes a housing for receiving a pressurized dispensing container of medicament and a mouthpiece for insertion into the mouth or a user of the inhaler. An outlet in the housing communicates with the mouth piece via a duct ending in an outlet. At least one air inlet is provided for allowing air into the inhaler. The air inlet(s) being positioned downstream relative to the duct outlet. A restricted airflow passage is provided between the air inlet(s) and a location adjacent to the outlet of the duct. The inhaler also includes a vortex generating arrangement positioned in the restricted airflow passage, such that, in use, when a user inhales through the mouthpiece, a swirling airflow is created from the inlet(s) to the mouthpiece along the passage towards the duct outlet.

Abstract: A metering valve for dispensing an accurately metered dose of a product includes a valve stem having at one end a piston extending within and slidable relative to a cup shaped valve body. A spring member urges the piston against a base of the valve body. Movement of the valve stem against the spring action causes the piston to move away from the base of the valve body to define a temporary metering chamber between the valve stem and valve body. A clearance between an outer surface of the piston and an inner surface of the valve body provides a path for the product to flow from the container to the metering chamber. A seal within the container is contacted by an end of the piston to prevent the flow of product along the path, and the product is dispensed from the temporary metering chamber through an outlet in the valve stem.

Abstract: The invention relates to an inhaler for products such as medicaments, and particularly to an inhaler for transferring to a patient, at a controlled air flow, a metered dose of a medicament contained in a pressurised dispensing container. The inhaler includes a housing adapted to receive a pressurised dispensing container, a mouthpiece, a duct connecting the container outlet with the mouthpiece, and an air inlet arrangement having at least one air inlet for allowing air into the inhaler when a user applies suction to the mouthpiece. The air inlet arrangement also has an air flow controller in which a piston member with a tapering external surface is movable due to a pressure change when suction is applied to the mouthpiece. The resulting piston movement effects a change in the flow of air through the air inlet. The air flow controller also includes a spring for urging the piston member to a rest position to allow maximum air flow to the air inlet.

Abstract: The invention relates to an inhaler for products such as medicaments, and particularly to an inhaler for transferring to a patient a metered dose of product contained in a pressurized dispensing container. The inhaler includes a housing adapted to receive a pressurized dispensing container, a mouthpiece, duct means for connecting an outlet of the container with the mouthpiece and air inlet means for allowing air into the inhaler for when a user applies suction to the mouthpiece. The housing also comprises a mechanical break-up component located in the duct means. The component breaks up the product as it passes along the duct means, before mixing with the air flow to effect atomization of the product. The duct means includes a chamber for receiving the mechanical break-up component, the chamber having an end wall providing a barrier between the chamber and the mouthpiece to prevent the mechanical break-up component from entering the mouthpiece.