Patents by Inventor David I. Devore
David I. Devore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8962757Abstract: Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.Type: GrantFiled: November 26, 2008Date of Patent: February 24, 2015Assignee: Rutgers, The State University of New JerseyInventors: David I. Devore, Charles Roth
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Publication number: 20110021602Abstract: Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.Type: ApplicationFiled: November 26, 2008Publication date: January 27, 2011Inventors: David I. Devore, Charles Roth
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Publication number: 20090324695Abstract: Biocompatible composites of flexible polymers/copolymers films and dispersed solid silica-based ceramic microparticles are provided. The composites uniquely combine material and drug delivery properties that are essential for wound dressings and drug delivery applications. The flexible copolymer films are preferably tyrosine-based polycarbonates, and the ceramic microparticles are biodegradable silica-based glass particles that are preferably processed by a sol-gel methodology. The copolymers and the ceramic microparticles independently can contain therapeutic agents, are independently capable of binding these agents, and can independently release such agents. It is sufficient that either the polymer or the ceramic contains therapeutic agents, although both may contain them.Type: ApplicationFiled: June 1, 2009Publication date: December 31, 2009Inventors: Paul Ducheyne, David I. Devore
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Patent number: 6472440Abstract: Defoamers are the products of the reaction of epichlorohydrin and compounds having the formula II R3(EO)n(PO)mOH (II) wherein R3 is an alkyl, alkenyl or arenyl group having from 4 to 22 carbon atoms; a substituted alkyl or alkenyl group having from 4 to 22 carbon atoms wherein; n is a number from 0 to 50 and m is a number from 0 to 10; wherein the mole ratio of epichlorohydrin to (II) is from about 0.60/1 to about 2/1 are extremely efficient defoamers for aqueous surfactant systems. The defoamers are added to a surfactant in an amount sufficient to reduce or eliminate foam and have the advantage of being totally dispersible in water, are readily biodegradable, contain no organic solvents and do not affect the detergency of surfactants with which they are used because they are nonionic surfactants in themselves.Type: GrantFiled: April 14, 1999Date of Patent: October 29, 2002Assignee: Cognis CorporationInventors: Stephen F. Gross, Michael S. Wiggins, Ronald W. Broadbent, David I. Devore
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Publication number: 20010051661Abstract: Defoamers are the products of the reaction of epichlorohydrin and compounds having the formula IIType: ApplicationFiled: April 14, 1999Publication date: December 13, 2001Inventors: STEPHEN F. GROSS, MICHAEL S. WIGGINS, RONALD W. BROADBENT, DAVID I. DEVORE
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Patent number: 6110977Abstract: Products of the reaction of epichlorohydrin and compounds having the formula IIR.sub.3 (EO).sub.n (PO).sub.m OH (II)wherein R.sub.3 is an alkyl, alkenyl or arenyl group having from 4 to 22 carbon atoms; a substituted alkyl or alkenyl group having from 4 to 22 carbon atoms wherein; n is a number from 0 to 50 and m is a number from 0 to 10; wherein the mole ratio of epichlorohydrin to (II) is from about 0.60/1 to about 2/1 are extremely efficient defoamers for aqueous surfactant systems are effective as defoamers, viscosity reducers and crystallization preventives for aqueous surfactant solutions, particularly alkyl polyglycosides.Type: GrantFiled: June 10, 1998Date of Patent: August 29, 2000Assignee: Henkel CorporationInventors: Stephen F. Gross, Michael S. Wiggins, Ronald W. Broadbent, David I. Devore, Timothy C. Morris
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Patent number: 6077900Abstract: An aqueous dispersion containing a polyamide and non-polyamide polymer is prepared by dissolving the polyamide in an organic solvent with a surfactant to form a polyamide solution. Water is then added to the polyamide solution to form an aqueous dispersion. The non-polyamide polymer can be added before or after the addition of water. The polyamide/non-polyamide dispersion can be used to produce an ink with better adhesion to plastic substrates and reduced blocking problems.Type: GrantFiled: September 29, 1998Date of Patent: June 20, 2000Assignee: Cognis CorporationInventors: Chase J. Boudreaux, Timothy Vogel, David I. Devore, Reimar Heucher, Stephen A. Fischer, Kartar S. Arora
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Patent number: 6036817Abstract: The efficiency by which pulp cooking liquor components penetrate the wood and enable lignin and resins to be removed from the cellulosic materials is increased by contacting wood chips and the like with a liquid mixture comprised of white liquor containing at least one surfactant selected from the group consisting of a polymethylalkylsiloxane; a co- and terpolymer of silicone and a polyhydric alcohol; an alkoxylated aryl phosphate; an alkoxylated branched alkyl phosphate; an alkoxylated branched alcohol; an alkyl polyglycoside, an alkoxylated alkyl polyglycoside; a mixture of alkali metal salts of alkyl aromatic sulfate, a sulfosuccinate and a silicone; and combinations thereof; for a residence time effective to extract resinous components without substantial degradation of cellulose and thereafter heating at least a portion of the resulting mixture and wood chips.Type: GrantFiled: November 17, 1997Date of Patent: March 14, 2000Assignee: Henkel CorporationInventors: Marie-Esther Saint Victor, David I. Devore, Barbara Balos Bowker, John J. Palmer, Vincent T. Stine
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Patent number: 5922088Abstract: A process for fixing dyes impregnated in fine-dimensional synthetic textile substrates in an environmentally safe manner. The process comprises contacting the dyed synthetic substrates with a phenol- and formaldehyde-free dye-fixative composition comprising:(a) polymethacrylic acid,(b) copolymers of methacrylic acid consisting essentially of methacrylic acid and an ethylenically unsaturated comonomer selected from the group consisting of 2-acrylamido-2-methyl-propanesulfonic acid, sodium vinyl sulfonate, sodium styrene sulfonate, alkyl acrylate,(c) sulfamic acid, and(d) combinations of (a), (b) and (c).Type: GrantFiled: November 19, 1997Date of Patent: July 13, 1999Assignee: Henkel CorporationInventors: Howard Cole, Brian Francois, David I. Devore
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Patent number: 5895605Abstract: Defoamers are the products of the reaction of epichlorohydrin and compounds having the formula IIR.sub.3 (EO).sub.n (PO).sub.m OH (II)wherein R.sub.3 is an alkyl, alkenyl or arenyl group having from 4 to 22 carbon atoms; a substituted alkyl or alkenyl group having from 4 to 22 carbon atoms wherein; n is a number from 0 to 50 and m is a number from 0 to 10; wherein the mole ratio of epichlorohydrin to (II) is from about 0.60/1 to about 2/1 are extremely efficient defoamers for aqueous surfactant systems. The defoamers are added to a surfactant in an amount sufficient to reduce or eliminate foam and have the advantage of being totally dispersible in water, are readily biodegradable, contain no organic solvents and do not affect the detergency of surfactants with which they are used because they are nonionic surfactants in themselves.Type: GrantFiled: September 4, 1997Date of Patent: April 20, 1999Assignee: Henkel CorporationInventors: Stephen F. Gross, Michael S. Wiggins, Ronald W. Broadbent, David I. Devore
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Patent number: 5877245Abstract: The reaction product ofA) a linking compound of formula IR.sup.1 (X).sub.3 (I)wherein each X group is a halogen or one X group is a halogen and two X groups with 2 carbon atoms from the R.sup.1 group and an oxygen atom form an epoxy group, and R.sup.1 is an alkanetriyl group containing from 3 to 10 carbon atoms;B) a compound of formula IIR.sup.2 (OA).sub.n --OH (II)wherein R.sup.2 is an aliphatic group containing from 4 to 36 carbon atoms, n is a number of from 1 to 200, and each OA group is independently an ethyleneoxy, 1,2-propyleneoxy, or 1,2-butyleneoxy group; andC) a compound of formula IIIH--(OA).sub.m --OH (III)wherein OA is as defined above, and m is a number of from 1 to 500;processes for its preparation; and methods for its use as a thickener in aqueous compositions.Type: GrantFiled: August 15, 1997Date of Patent: March 2, 1999Assignee: Henkel CorporationInventors: Michael S. Wiggins, David I. Devore
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Patent number: 5827453Abstract: Defoamers are the products of the reaction of epichlorohydrin and compounds having the formula IIR.sub.3 (EO).sub.n (PO).sub.m OH (II)wherein R.sub.3 is an alkyl, alkenyl or arenyl group having from 4 to 22 carbon atoms; a substituted alkyl or alkenyl group having from 4 to 22 carbon atoms wherein; n is a number from 0 to 50 and m is a number from 0 to 10; wherein the mole ratio of epichlorohydrin to (II) is from about 0.60/1 to about 2/1 are extremely efficient defoamers for aqueous surfactant systems. The defoamers are added to a surfactant in an amount sufficient to reduce or eliminate foam and have the advantage of being totally dispersible in water, are readily biodegradable, contain no organic solvents and do not affect the detergency of surfactants with which they are used because they are nonionic surfactants in themselves.Type: GrantFiled: January 14, 1997Date of Patent: October 27, 1998Assignee: Henkel CorporationInventors: Stephen F. Gross, Michael S. Wiggins, Ronald W. Broadbent, David I. Devore
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Patent number: 5804682Abstract: A process is provided for preparing a dispersion of a polyamide in water, said process comprising:forming a solution of a polyamide having an acid value of greater than about 2 in an organic solvent to form a solution of said polyamide in said solvent, said polyamide and said solvent being at a temperature below the softening point of said polyamide during said dissolving, said solution further comprising a surfactant, wherein at least a portion of the acid value of said polyamide is neutralized,adding sufficient water to said solution with mixing to form an oil-in-water dispersion, the temperature of said solution and said water being below the softening point of said polyamide during said adding, andremoving at least a major amount of said organic solvent from said oil-in-water dispersion. The resulting dispersion is useful in preparing a coating of the polyamide, which coating is useful as an adhesive.Type: GrantFiled: October 25, 1996Date of Patent: September 8, 1998Assignee: Henkel CorporationInventors: Stephen A. Fischer, David I. Devore, Kartar S. Arora, Reimar Heucher, Michael S. Wiggins, Chase J. Boudreaux, Dwight D. Heinrich
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Patent number: 5770680Abstract: A process is provided for preparing a dispersion of a polyamide in water, said process comprising:dissolving a polyamide having an amine value of greater than about 2 in an organic solvent to form a solution of said polyamide in said solvent, said polyamide and said solvent being at a temperature below the softening point of, said polyamide during said dissolving, said solution further comprising a surfactant and an inorganic alkaline material,adding sufficient water containing an acid to said solution with mixing to form an oil-in-water dispersion, the temperature of said solution and said water being below the softening point of said polyamide during said adding, the amount of said acid being sufficient to neutralize a portion of said inorganic alkaline material, but insufficient to coagulate said polyamide from the resulting oil-in-water dispersion, andremoving at least a major amount of said organic solvent from said oil-in-water dispersion.Type: GrantFiled: October 25, 1996Date of Patent: June 23, 1998Inventors: Stephen A. Fischer, David I. Devore, Kartar S. Arora, Reimar Heucher
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Patent number: 5728265Abstract: The efficiency by which pulp cooking liquor components penetrate the wood and enable lignin and resins to be removed from the cellulosic materials is increased by contacting wood chips and the like with a liquid mixture comprised of white liquor containing at least one surfactant selected from the group consisting of a polymethylalkylsiloxane; a co- and terpolymer of silicone and a polyhydric alcohol; an alkoxylated aryl phosphate; an alkoxylated branched alkyl phosphate; an alkoxylated branched alcohol; an alkyl polyglycoside, an alkoxylated alkyl polyglycoside; a mixture of alkali metal salts of alkyl aromatic sulfate, a sulfosuccinate and a silicone; and combinations thereof; for a residence time effective to extract resinous components without substantial degradation of cellulose and thereafter heating at least a portion of the resulting mixture and wood chips.Type: GrantFiled: April 15, 1996Date of Patent: March 17, 1998Assignee: Henkel CorporationInventors: Marie-Esther Saint Victor, David I. Devore, Barbara Balos Bowker, John J. Palmer, Vincent T. Stine
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Patent number: 5723538Abstract: A process is provided for preparing a dispersion of a polyamide in water, said process comprising:dissolving a polyamide having an amine value of greater than about 2 in an organic solvent to form a solution of said polyamide in said solvent, said polyamide and said solvent being at a temperature below the softening point of said polyamide during said dissolving, said solution further comprising a surfactant and an inorganic alkaline material,adding sufficient water containing an acid to said solution with mixing to form an oil-in-water dispersion, the temperature of said solution and said water being below the softening point of said polyamide during said adding, the amount of said acid being sufficient to neutralize a portion of said inorganic alkaline material, but insufficient to coagulate said polyamide from the resulting oil-in-water dispersion, andremoving at least a major amount of said organic solvent from said oil-in-water dispersion.Type: GrantFiled: October 25, 1996Date of Patent: March 3, 1998Assignee: Henkel CorporationInventors: Stephen A. Fischer, David I. Devore, Kartar S. Arora, Reimar Heucher, Michael S. Wiggins, Chase J. Boudreaux
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Patent number: 5648409Abstract: There is disclosed a self-disbursing curable epoxy resin composition comprising the addition product of reactants comprising (a) 1.0 reactive equivalent of an epoxy resin, (b) from about 0.40 to 0.95 reactive equivalents of a polyhydric phenol, and (c) from about 0.005 to 0.5 reactive equivalents of an amine-epoxy adduct comprising the addition product of reactants comprising 1.0 reactive equivalent of an aromatic polyepoxide and from about 0.3 to 0.9 reactive equivalents of a polyoxyalkyleneamine.Type: GrantFiled: December 29, 1994Date of Patent: July 15, 1997Assignee: Henkel CorporationInventors: Kartar S. Arora, David I. Devore, Reuben H. Grinstein, Grannis S. Johnson, John G. Papalos, Shailesh Shah
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Patent number: 5575892Abstract: A composition for improving the wet strength of cellulosic fibrous webs is comprised of an aminopolyamide-epichlorohydrin acid salt resin having an E/N ratio of from about 0.6 to about 2.0 and from about 1% to about 35% of a water soluble cationic polymer based on the weight of the resin. The composition has a total organic chlorine content of from about 0.5% to 1.0% by weight based on the weight of the aminopclyamide-epichlorohydrin acid salt resin.Type: GrantFiled: June 5, 1995Date of Patent: November 19, 1996Assignee: Henkel CorporationInventors: David I. Devore, Nancy Clungeon, Stephen A. Fischer
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Patent number: 5503713Abstract: A process for making a cellulosic pulp fiber web having increased wet strength comprising the steps of: (1) adding to an aqueous cellulosic pulp fiber slurry a water soluble cationic polymer consisting of polydimethyldiallylammonium chloride to form a first treated slurry; (2) adding to the first treated slurry an aminopolyamide-epichlorohydrin acid salt resin solution having an E/N ratio of from about 0.6 to about 2.0 so that the weight percent of the cationic polymer is from about 1% to about 35% based on the weight of the resin, thus forming a second treated slurry; and (3) forming a cellulosic pulp fiber web by dewatering the second treated slurry.Type: GrantFiled: July 1, 1994Date of Patent: April 2, 1996Assignee: Henkel CorporationInventors: David I. Devore, Nancy Clungeon, Stephen A. Fischer
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Patent number: 5408024Abstract: A resin composition containing from about 10 to 95% by weight of n-methylolacrylamide and from about 5 to 90% by weight of a cationic monomer and optionally a nonionic monomer and/or a difunctional monomer.Type: GrantFiled: March 14, 1994Date of Patent: April 18, 1995Assignee: Henkel CorporationInventors: Stephen A. Fischer, David I. Devore