Patents by Inventor David I. Stirling

David I. Stirling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pyridine-2,3-dicarboxylic acids
    Patent number: 5166060
    Abstract: Pyridine-2,3-dicarboxylic acids are prepared by the action of 2,3-dihydroxybenzoate-3,4-dioxygenase on 2,3-dihydroxybenzoic acids in a liquid medium which lacks active decarboxylase and which has a pH from 4 to 9, an ionic strength below about 1 molar, and a low concentration of metal cations and complex anions. In close temporal proximity, the 2-hydroxy-3-carboxymuconic acid semialdehyde which forms is allowed to react with a source of ammonia or a primary amine, avoiding substantial decarboxylation.
    Type: Grant
    Filed: March 31, 1989
    Date of Patent: November 24, 1992
    Assignee: Celgene Corporation
    Inventors: Randall A. Roehl, George W. Matcham, David I. Stirling
  • Novel heteropolysaccharide
    Patent number: 5071976
    Abstract: This invention provides a fermentation process which involves aerobically cultivating a strain of Methylophilus viscogenes under growth conditions to produce an accumulated quantity of a novel type of exopolysaccharide, such as heteropolysaccharide Poly 54.
    Type: Grant
    Filed: November 7, 1988
    Date of Patent: December 10, 1991
    Assignee: Celgene Corporation
    Inventor: David I. Stirling
  • Enantiomeric enrichment and stereoselective synthesis of chiral amines
    Patent number: 4950606
    Abstract: Amines in which the amino group is on a secondary carbon atom which is chrially substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other.
    Type: Grant
    Filed: June 22, 1989
    Date of Patent: August 21, 1990
    Assignee: Celgene Corporation
    Inventors: David I. Stirling, Andrew L. Zeitlin, George W. Matcham
  • Oxidation processes
    Patent number: 4837150
    Abstract: A process in which a culture of a methane-oxidizing bacterium or an extract thereof containing a methane oxidizing system is used as oxidizing agent for the oxidation of a higher short-chain alkane, an alkene or a cyclic organic compound.
    Type: Grant
    Filed: December 9, 1985
    Date of Patent: June 6, 1989
    Assignee: National Research Development Corporation
    Inventors: Howard Dalton, John Colby, David I. Stirling
  • Process for culturing methylophilus methylotrophus
    Patent number: 4652527
    Abstract: This invention provides a process for single cell protein production which involves the culturing of Methylophilus methylotrophus microorganisms by facultative growth on glucose as a carbon and energy source.
    Type: Grant
    Filed: October 9, 1984
    Date of Patent: March 24, 1987
    Assignee: Celanese Corporation
    Inventor: David I. Stirling
  • Microbiological process for oxidizing organic compounds
    Patent number: 4594324
    Abstract: A process in which a culture of a methane-oxidizing bacterium or an extract thereof containing a methane oxidizing system is used as oxidizing agent for the oxidation of a higher short-chain alkane, an alkene or a cyclic organic compound.
    Type: Grant
    Filed: December 28, 1982
    Date of Patent: June 10, 1986
    Assignee: National Research Development Corp.
    Inventors: Howard Dalton, John Colby, David I. Stirling