Abstract: Acyclic CB[n]-type compounds, methods of making such compounds, and uses of the compounds. For example, these compounds can be used as nanocontainers to solubilize pharmaceutical agents. Also provided are compositions and methods of using them for therapy or prophylaxis of a wide variety of conditions for which therapy or prophylaxis is desirable.

Abstract: A data migration and integration system is disclosed. In various embodiments, the system includes a memory configured to store a mapping from a source schema to a target schema; and a processor coupled to the memory and configured to migrate to a target schema an instance of source data organized according to the source schema, including by using a chase engine to perform an ordered sequence of steps comprising adding a bounded layer of new elements to a current canonical chase state associated with migrating the source data to the target schema; adding coincidences associated with one or more of the target schema data integrity constraints and a mapping from the source schema to the target schema; and merging equal elements based on the coincidences; and repeat the preceding ordered sequence of steps iteratively until an end condition is met.

Abstract: This application relates to improvements in environments for microbial testing. Exemplary embodiments provide a uniquely configured tray containing an environment conditioning material, such as an oxygen scavenger material, for use with a cassette assembly. Furthermore, some embodiments provide a cutting mechanism that allows the tray to be reliably breached, thereby exposing the material inside to the environment. Some embodiments can cut open the material with specially-configured cutter teeth, which can easily be deployed by twisting or pushing two halves of the cassette assembly.

Abstract: This application relates to improvements in environments for microbial testing. Exemplary embodiments provide a uniquely configured tray containing an environment conditioning material, such as an oxygen scavenger material, for use with a cassette assembly. Furthermore, some embodiments provide a cutting mechanism that allows the tray to be reliably breached, thereby exposing the material inside to the environment. Some embodiments can cut open the material with specially-configured cutter teeth, which can easily be deployed by twisting or pushing two halves of the cassette assembly.

Abstract: The present application relates to compounds of Formula (I) or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment of diseases, disorders or conditions that are treatable by inhibiting or blocking NUAK kinase, such as cancers and fibrosis.

Abstract: Techniques are discussed herein for detecting and measuring faults within vehicle drive systems. In various implementations, actuator feedback monitors and/or vehicle performance monitors are used individually or in combination to determine faults within acceleration systems, braking systems, and/or steering systems of a vehicle. Different monitors may use different algorithms, models, and input data from the vehicle during operation, to compare a predicted drive system output to a corresponding measured output. Additionally, monitors may include associated sets of disable conditions used to distinguish drive system faults from other driving conditions. The outputs from actuator feedback monitors, vehicle performance monitors, and disable conditions may be analyzed to detect drive system faults and control the vehicle to address the faults and control the safe operation of the vehicle.

Abstract: Acyclic CB[n]-type compounds, methods of making such compounds, and uses of the compounds. For example, these compounds can be used as nanocontainers to solubilize pharmaceutical agents. Also provided are compositions and methods of using them for therapy or prophylaxis of a wide variety of conditions for which therapy or prophylaxis is desirable.

Abstract: An electric vehicle includes a frame, a wheel coupled to the frame, and a battery assembly including a housing supported by the frame. The housing includes a top side and a bottom side opposite the top side. A drive assembly of the electric vehicle is at least partially enclosed within a drive housing unit. The drive assembly includes a motor configured to receive power from the battery assembly and a gear assembly configured to transmit torque from the motor to the wheel. The drive housing unit is positioned below the bottom side of the housing.

Abstract: This disclosure relates to a method for anonymous attestation that includes receiving, by an application running on a client device and from a first content provider, an authentication request to authenticate a user to receive content from a second domain of a second content provider, redeeming, with an attestation token issuing system that issued an anonymous attestation token attesting to the user's authentication to the second content provider, the anonymous attestation token by transmitting the anonymous attestation token with a second request, receiving a redemption result representing whether the attestation token was successfully redeemed, signed by the attestation token issuing system using a digital signature and is operable to verify, to the second content provider, that the user is authenticated to the second content provider without identifying the user to the second content provider, and transmitting, to the first content provider, the redemption result.

Abstract: A data migration and integration system is disclosed. In various embodiments, the system includes a memory configured to store a mapping from a source schema to a target schema; and a processor coupled to the memory and configured to migrate to a target schema an instance of source data organized according to the source schema, including by using a chase engine to perform an ordered sequence of steps comprising adding a bounded layer of new elements to a current canonical chase state associated with migrating the source data to the target schema; adding coincidences associated with one or more of the target schema data integrity constraints and a mapping from the source schema to the target schema; and merging equal elements based on the coincidences; and repeat the preceding ordered sequence of steps iteratively until an end condition is met.

Abstract: A system generates haptic feedback in an electric vehicle. The system comprises a frame, an energy storage device, and a wheel rotatably coupled to the frame. A motor receives power from the energy storage device and provides torque to the wheel. A controller determines a first operational state of the electric vehicle and transmits a first torque signal to the motor to control the motor to transmit first torque levels to the wheel to propel the electric vehicle. The controller determines a second operational state of the electric vehicle and transmits a second torque signal to the motor assembly. The motor assembly transmits second torque levels to the wheel to generate haptic feedback. The second torque signal is based on the second operational state of the electric vehicle and a torque profile stored in the memory, where the torque profile defines an irregular-shaped periodic waveform (e.g., a heartbeat rhythm).

Abstract: An electric vehicle includes a frame, a wheel coupled to the frame, and a battery assembly including a housing supported by the frame. The housing includes a top side and a bottom side opposite the top side. A drive assembly of the electric vehicle is at least partially enclosed within a drive housing unit. The drive assembly includes a motor configured to receive power from the battery assembly and a gear assembly configured to transmit torque from the motor to the wheel. The drive housing unit is positioned below the bottom side of the housing.

Abstract: Disclosed herein are acyclic sulfated cucurbit[n]uril containing sulfate substituent(s), compositions containing the same, and method of preparation thereof. These compounds are useful, for example, as sequestering agents for drugs of abuse.

Abstract: Provided are sulfated pillararenes and methods of making and using same. The pillararenes have macrocycle core having a plurality of aryl groups, attached (e.g., covalently bonded) in a para orientation to the adjacent methylene groups. The pillararenes have a hydrophobic cavity. The hydrophobic cavity may be used to sequester various materials or to deliver materials sequestered therein.

Abstract: A material reduction machine includes a prime mover driving a cutting mechanism. A drive system receives a signal to initiate rotation of a cutting mechanism. A sensor senses a machine load parameter and reports a signal to a controller operatively coupled to the clutch to control sequential engagement cycles from the engine to the cutting mechanism. The controller utilizes a stored first disengagement threshold value for stopping a first engagement cycle and continues monitoring the signal as the machine load parameter increases momentarily after reaching the first disengagement threshold. The controller determines and adopts a second disengagement threshold value based on observation of the machine load parameter indicative of maximum load during the continued monitoring after the first disengagement threshold is realized, and further being based on a stored correction factor. The second disengagement threshold value is used for a second engagement cycle.

Abstract: A system generates haptic feedback in an electric vehicle. The system comprises a frame, an energy storage device, and a wheel rotatably coupled to the frame. A motor receives power from the energy storage device and provides torque to the wheel. A controller determines a first operational state of the electric vehicle and transmits a first torque signal to the motor to control the motor to transmit first torque levels to the wheel to propel the electric vehicle. The controller determines a second operational state of the electric vehicle and transmits a second torque signal to the motor assembly. The motor assembly transmits second torque levels to the wheel to generate haptic feedback. The second torque signal is based on the second operational state of the electric vehicle and a torque profile stored in the memory, where the torque profile defines an irregular-shaped periodic waveform (e.g., a heartbeat rhythm).

Abstract: An electric vehicle includes a frame, a wheel coupled to the frame, and a battery assembly including a housing supported by the frame. The housing includes a top side and a bottom side opposite the top side. A drive assembly of the electric vehicle is at least partially enclosed within a drive housing unit. The drive assembly includes a motor configured to receive power from the battery assembly and a gear assembly configured to transmit torque from the motor to the wheel. The drive housing unit is positioned below the bottom side of the housing.

Abstract: The invention comprises a beeswax analogue composition which enables the efficient replacement thereof, for beekeeping and any industries that normally use it in their production processes and products, based on a harmless natural organic mixture free of contamination having chemical and physical aspects similar or equal to said wax, which comprises: Fine crystal wax, known as microcrystalline wax, with a high percentage of hydrocarbon, branched, isoparaffinic and naphthenic hydrocarbons. Macrocrystalline wax made of non-branched alkanes of non-fine crystals. Organic resin. Organic pigment to determine the colour, distinguishing region, place and factory batch. (Published in a timely manner, to prevent falsifications). The method of preparation comprises the following steps, tools and actions: Proportional weighing of components. Verification of asepsis of machines and tools.

Abstract: A data migration and integration system is disclosed. In various embodiments, the system includes a memory configured to store a mapping from a source schema to a target schema; and a processor coupled to the memory and configured to migrate to a target schema an instance of source data organized according to the source schema, including by using a chase engine to perform an ordered sequence of steps comprising adding a bounded layer of new elements to a current canonical chase state associated with migrating the source data to the target schema; adding coincidences associated with one or more of the target schema data integrity constraints and a mapping from the source schema to the target schema; and merging equal elements based on the coincidences; and repeat the preceding ordered sequence of steps iteratively until an end condition is met.

Abstract: An electric vehicle includes a frame, a wheel coupled to the frame, and a battery assembly including a housing supported by the frame. The housing includes a top side and a bottom side opposite the top side. A drive assembly of the electric vehicle is at least partially enclosed within a drive housing unit. The drive assembly includes a motor configured to receive power from the battery assembly and a gear assembly configured to transmit torque from the motor to the wheel. The drive housing unit is positioned below the bottom side of the housing.