Patents by Inventor David J. Bacino

David J. Bacino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Erythromycin derivatives
    Patent number: 5288709
    Abstract: New 9-deoxo-9,12-epoxy erythromycin derivatives are disclosed which have improved antibacterial properties. Compositions comprising the erythromycin derivatives and methods of treating mammalian patients with the erythromycin derivatives are also disclosed.
    Type: Grant
    Filed: August 21, 1991
    Date of Patent: February 22, 1994
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, Larry L. Klein, Clinton M. Yeung, Carla M. Edwards, David J. Bacino
  • Erythromycin A 11,12-carbonates and method of use
    Patent number: 4686207
    Abstract: Disclosed herein are erythromycin derivatives of the formula ##STR1## wherein R.sub.1 is lower alkyl, aryl, alkene, aryl halide, alkylamino, hydroxyalkyl and furanyl, and pharmaceutically acceptable salts thereof. These compounds have improved oral absorption, reduced effects on gastrointestinal motility, increased acid stability and longer serum half-lives.
    Type: Grant
    Filed: November 12, 1985
    Date of Patent: August 11, 1987
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, David J. Bacino
  • 3-Amino-3-demethoxyfortimicins, pharmaceutical compositions thereof and method of use
    Patent number: 4427662
    Abstract: Disclosed herein are fortimicin derivatives represented by the formula: ##STR1## wherein R is hydrogen, loweralkyl, aminoloweralkyl, diaminoloweralkyl, N-loweralkylaminoloweralkyl, N,N-diloweralkylaminoloweralkyl, hydroxyloweralkyl, aminohydroxyloweralkyl, N-loweralkylaminohydroxyloweralkyl, N,N-diloweralkylaminohydroxyloweralkyl, loweracyl, aminoloweracyl, diaminoloweracyl, hydroxyloweracyl, N-loweralkylaminoloweracyl, N,N-diloweralkylaminoloweracyl, or aminohydroxyloweracyl, and the pharmaceutically acceptable salts thereof. Also disclosed are intermediates useful in the preparation of these compounds and compositions of these compounds together with a pharmaceutically acceptable carrier and/or diluent.
    Type: Grant
    Filed: April 9, 1982
    Date of Patent: January 24, 1984
    Assignee: Abbott Laboratories
    Inventors: John S. Tadanier, Robert Hallas, Leslie A. Freiberg, David J. Bacino