Patents by Inventor David J. Garfinkel

David J. Garfinkel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Simple method for detecting inhibitors of retroviral replication
    Patent number: 5714313
    Abstract: The present invention relates, in general, to a DNA segment. In particular, the present invention relates to a DNA segment comprising a selectable marker gene, a DNA segment comprising a selectable marker gene inserted into a retrotransposon, cells containing these DNA segments, and methods of using these DNA segments and cells. The present invention further relates to a vector comprising a selectable marker gene inserted into a retrotransposon, wherein the retrotransposon comprises a retroviral reverse transcriptase/RNase H gene domain and wherein the selectable marker gene contains an intron inserted into a coding sequence of the marker gene and the intron is in antisense orientation relative to transcription of the marker gene and in sense orientation relative to transcription of the retrotransposon.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: February 3, 1998
    Assignee: United States of America as represented by the Department of Health and Human Services
    Inventors: David J. Garfinkel, Dwight V. Nissley, Joan M. Curcio, Jeffrey N. Strathern
  • DNA for use in a simple method for detecting inhibitors of retrotransposition
    Patent number: 5462873
    Abstract: The present invention relates, in general, to a DNA segment. In particular, the present invention relates to a DNA segment comprising a selectable marker gene, a DNA segment comprising a selectable marker gene inserted into a retrotransposon, cells containing these DNA segments, and methods of using these DNA segments and cells.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: October 31, 1995
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David J. Garfinkel, M. Joan Curcio