Patents by Inventor David J. Hosfield

David J. Hosfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kinase inhibitors
    Patent number: 8288536
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: October 16, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • Imidazopyridine compounds
    Patent number: 8124617
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of formula (I) wherein the variables are as defined herein.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: February 28, 2012
    Assignees: Takeda San Diego, Inc., Takeda Pharmaceutical Company Limited
    Inventors: Hidehisa Iwata, Yasuhisa Kohara, Sheldon X. Cao, Prasuna Guntupalli, Stephen L. Gwaltney, David J. Hosfield, Yan Liu, Jeffrey A Stafford, Beverly Wolgast
  • GLUCOKINASE ACTIVATORS
    Publication number: 20110275665
    Abstract: Compounds are provided for use with hexokinases that comprise: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: July 18, 2011
    Publication date: November 10, 2011
    Applicant: TAKEDA SAN DIEGO, INC.
    Inventors: Sheldon X. Cao, Jun Feng, Stephen L. Gwaltney, David J. Hosfield, Robert J. Skene, Jeffrey A. Stafford, Mingnam Tang
  • Substituted indazoles as glucokinase activators
    Patent number: 8008332
    Abstract: Compounds are provided for use with hexokinases that comprise: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: August 30, 2011
    Assignee: Takeda San Diego, Inc.
    Inventors: Sheldon X. Cao, Jun Feng, Stephen L. Gwaltney, David J. Hosfield, Robert J. Skene, Jeffrey A. Stafford, Mingnam Tang
  • GLUCOKINASE ACTIVATORS
    Publication number: 20110070297
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: December 1, 2010
    Publication date: March 24, 2011
    Applicants: Takeda San Diego, Inc., Takeda Pharmaceutical Company Limited
    Inventors: Sheldon X. Cao, Jun Feng, Yasuhiro Imaeda, Stephen L. Gwaltney, David J. Hosfield, Nobuyuki Takakura, Mingnam Tang
  • KINASE INHIBITORS
    Publication number: 20100216765
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: April 6, 2010
    Publication date: August 26, 2010
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • Kinase inhibitors
    Patent number: 7713973
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: May 11, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • IMIDAZOPYRIDINE COMPOUNDS
    Publication number: 20100069431
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of formula (I) wherein the variables are as defined herein.
    Type: Application
    Filed: September 1, 2006
    Publication date: March 18, 2010
    Inventors: Hidehisa Iwata, Yasuhisa Kohara, Sheldon X. Cao, Prasuna Guntupalli, Stephen L. Gwaltney, David J. Hosfield, Yan Liu, Jeffrey A. Stafford, Beverly Throop
  • Kinase Inhibitors
    Publication number: 20080153869
    Abstract: The invention relates to compounds having one of the below formulae that may be used to inhibit kinases as well as compositions of matter and kits comprising these compounds, and methods using the compounds.
    Type: Application
    Filed: June 13, 2005
    Publication date: June 26, 2008
    Inventors: Jerome C. Bressi, Anthony R. Gangloff, David J. Hosfield, Andrew J. Jennings, Bheema R. Paraselli, Jeffrey A. Stafford
  • Crystallization of dipeptidyl peptidase IV (DPPIV)
    Patent number: 7344852
    Abstract: Provided are crystals relating to DPPIV and its various uses.
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: March 18, 2008
    Assignee: Takeda San Diego, Inc.
    Inventors: Kathleen Aertgeerts, Ciaran N. Cronin, David J. Hosfield, Mark W. Knuth, Duncan E. McRee, Sridhar Prasad, Bi Ching Sang, Robert J. Skene, Robert A. Wijnands, Sheng Ye
  • Crystallization of MvaS (HMG-CoA Synthase)
    Patent number: 7252930
    Abstract: Provided are crystals relating to MvaS (HMG-CoA Synthase) and its various uses.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: August 7, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Alexei Brooun, David J. Hosfield, Robert J. Skene, Leslie W. Tari, Sheng Ye
  • Crystallization of 11-Beta-Hydroxysteroid Dehydrogenase type 1
    Patent number: 7241604
    Abstract: Provided are crystals relating to 11-Beta-Hydroxysteroid Dehydrogenase type 1 and its various uses.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: July 10, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Kathleen Aertgeerts, Oleg Brodsky, Ellen Chi, Mark T. Hilgers, David J. Hosfield, Robert J. Skene
  • Crystal structure of MvaS
    Patent number: 7076372
    Abstract: Provided are structure coordinates relating to MvaS and its various uses.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: July 11, 2006
    Assignee: Takeda San Diego, Inc.
    Inventors: Alexei Brooun, David J. Hosfield, Robert J. Skene, Leslie W. Tari, Sheng Ye